Specific Antiproliferative Properties of Proteinaceous Toxin Secretions from the Marine Annelid
Animals
Annelida
Antineoplastic Agents
/ isolation & purification
Apoptosis
/ drug effects
Cell Proliferation
/ drug effects
Cell Survival
/ drug effects
Dose-Response Relationship, Drug
Female
HCT116 Cells
Humans
K562 Cells
MCF-7 Cells
Marine Toxins
/ isolation & purification
Ovarian Neoplasms
/ drug therapy
cancer
cell cycle
cytotoxicity
invertebrate
ovarian cancer
programmed cell death
toxin
Journal
Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729
Informations de publication
Date de publication:
12 Jan 2021
12 Jan 2021
Historique:
received:
22
12
2020
revised:
08
01
2021
accepted:
08
01
2021
entrez:
15
1
2021
pubmed:
16
1
2021
medline:
20
5
2021
Statut:
epublish
Résumé
As Yondelis joins the ranks of approved anti-cancer drugs, the benefit from exploring the oceans' biodiversity becomes clear. From marine toxins, relevant bioproducts can be obtained due to their potential to interfere with specific pathways. We explored the cytotoxicity of toxin-bearing secretions of the polychaete
Identifiants
pubmed: 33445445
pii: md19010031
doi: 10.3390/md19010031
pmc: PMC7827603
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Marine Toxins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Fundação para a Ciência e a Tecnologia
ID : PTDC/BTA-BTA/28650/2017
Organisme : Fundação para a Ciência e a Tecnologia
ID : SFRH/BD/109462/2015
Organisme : Fundação para a Ciência e a Tecnologia
ID : CEECIND/02699/2017
Organisme : Fundação para a Ciência e a Tecnologia
ID : UID/NEU/04539/2019
Organisme : Fundação para a Ciência e a Tecnologia
ID : SAICTPAC/0010/2015
Organisme : Fundação para a Ciência e a Tecnologia
ID : PTDC/BTM-TEC/29311/2017
Organisme : Fundação para a Ciência e a Tecnologia
ID : PTDC/MEC-PSQ/30943/2017
Organisme : National Mass Spectrometry Network (RNEM)
ID : ROTEIRO/0028/2013
Références
Mar Drugs. 2015 Jan 07;13(1):202-21
pubmed: 25574736
Nature. 1970 Aug 15;227(5259):680-5
pubmed: 5432063
Nat Prod Rep. 2009 Mar;26(3):322-37
pubmed: 19240944
Nat Rev Cancer. 2002 Feb;2(2):143-8
pubmed: 12635177
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
Sci Rep. 2017 Jul 20;7(1):6000
pubmed: 28729681
J Mol Biol. 1990 Oct 5;215(3):403-10
pubmed: 2231712
Prostate Cancer Prostatic Dis. 2013 Sep;16(3):277-84
pubmed: 23835622
Bioinformatics. 2015 Mar 15;31(6):926-32
pubmed: 25398609
Environ Res. 2019 Jun;173:270-280
pubmed: 30928858
Biochim Biophys Acta. 2000 Mar 7;1477(1-2):146-56
pubmed: 10708855
EMBO J. 1997 Aug 15;16(16):4887-96
pubmed: 9305631
Curr Pharm Biotechnol. 2018;19(4):308-335
pubmed: 29929461
Proc Natl Acad Sci U S A. 2000 May 23;97(11):6049-54
pubmed: 10811911
Int J Biochem Cell Biol. 2013 Sep;45(9):1974-86
pubmed: 23811033
Oncogene. 2011 Aug 11;30(32):3477-88
pubmed: 21577205
Nat Cell Biol. 2004 Jun;6(6):507-14
pubmed: 15146192
Mar Drugs. 2019 Aug 23;17(9):
pubmed: 31443597
Eur J Cancer. 2018 Nov;103:356-387
pubmed: 30100160
Proc Natl Acad Sci U S A. 1983 Nov;80(22):6977-81
pubmed: 6580620
Bioessays. 2001 Oct;23(10):936-46
pubmed: 11598960
J Biol Chem. 2008 Oct 31;283(44):30010-4
pubmed: 18768474
PLoS One. 2015 Oct 07;10(10):e0129008
pubmed: 26444829
Insect Mol Biol. 2010 Feb;19 Suppl 1:11-26
pubmed: 20167014
Biomed Res Int. 2014;2014:203639
pubmed: 24683541
PLoS One. 2013 Sep 04;8(9):e72162
pubmed: 24023729
Oncogene. 2001 Jul 5;20(30):3949-58
pubmed: 11494123
Dalton Trans. 2016 Mar 28;45(12):5339-55
pubmed: 26905013
Toxicol Appl Pharmacol. 2018 Oct 15;357:50-61
pubmed: 30145175
FEBS Lett. 2008 Aug 20;582(19):2838-42
pubmed: 18625232
Int J Biol Macromol. 2017 Nov;104(Pt A):508-514
pubmed: 28636877
Biochim Biophys Acta. 2010 May;1802(5):472-7
pubmed: 20152898
J Comput Biol. 1994 Spring;1(1):39-50
pubmed: 8790452
PLoS One. 2018 Jan 23;13(1):e0191607
pubmed: 29360852
Oncogene. 2007 May 14;26(22):3291-310
pubmed: 17496923
J Cell Sci. 2007 Nov 15;120(Pt 22):3905-10
pubmed: 17989088
Mar Drugs. 2018 Nov 01;16(11):
pubmed: 30388749
Anticancer Agents Med Chem. 2018;18(4):521-528
pubmed: 29141557
Nat Methods. 2012 Jun 28;9(7):676-82
pubmed: 22743772
Front Mol Biosci. 2017 Jan 24;4:1
pubmed: 28174697
J Biochem Mol Toxicol. 2003;17(1):59-66
pubmed: 12616648
PLoS One. 2010 May 03;5(5):e10393
pubmed: 20454652
Mar Drugs. 2019 Aug 17;17(8):
pubmed: 31426556
J Biol Chem. 2002 Oct 25;277(43):40919-29
pubmed: 12167638
PLoS One. 2019 Apr 12;14(4):e0215391
pubmed: 30978253
Sci Rep. 2018 May 16;8(1):7635
pubmed: 29769587
Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24165-24172
pubmed: 32929019
J Exp Biol. 2017 Feb 1;220(Pt 3):425-436
pubmed: 27852754
Dalton Trans. 2019 Sep 14;48(34):13081-13093
pubmed: 31411239
Nucleic Acids Res. 2019 Jan 8;47(D1):D607-D613
pubmed: 30476243
Mol Cell Biol. 1999 Mar;19(3):1661-72
pubmed: 10022854
Med Oncol. 2016 Nov;33(11):130
pubmed: 27757782
J Cell Sci. 2005 Jul 15;118(Pt 14):3091-102
pubmed: 15985464
J Inorg Biochem. 2019 Oct;199:110789
pubmed: 31357066
Oncogene. 2000 Mar 2;19(10):1257-65
pubmed: 10713667
Oncotarget. 2017 Jul 18;8(40):68329-68337
pubmed: 28978120
Dalton Trans. 2016 Dec 21;45(47):19127-19140
pubmed: 27868117
Mol Ther Nucleic Acids. 2017 Jun 16;7:408-416
pubmed: 28624216
Cancer Metastasis Rev. 2012 Jun;31(1-2):173-94
pubmed: 22109081
Acta Biochim Pol. 2019 Jun 7;66(2):207-213
pubmed: 31172986
Sci Rep. 2019 Apr 2;9(1):5515
pubmed: 30940866
Annu Rev Genomics Hum Genet. 2005;6:355-79
pubmed: 16124866
Pathol Res Pract. 2019 Sep;215(9):152516
pubmed: 31262576
PLoS One. 2014 Sep 17;9(9):e103988
pubmed: 25230021
Toxins (Basel). 2018 Nov 28;10(12):
pubmed: 30487389
Nat Commun. 2012;3:1072
pubmed: 22990868
Radiographics. 2011 May-Jun;31(3):625-46
pubmed: 21571648
Dalton Trans. 2017 Jul 25;46(29):9591-9604
pubmed: 28702618
Nat Methods. 2012 Jul;9(7):671-5
pubmed: 22930834
J Biol Chem. 2018 Jul 13;293(28):11076-11087
pubmed: 29794138
J Cell Biol. 1965 May;25:407-8
pubmed: 14287192
J Anat. 2018 Nov;233(5):567-579
pubmed: 30073651
Glia. 2000 Mar;30(1):39-48
pubmed: 10696143
Nature. 1997 Jun 19;387(6635):773-6
pubmed: 9194558
J Exerc Rehabil. 2016 Aug 31;12(4):255-9
pubmed: 27656620