Discovery of Cysteine and Its Derivatives as Novel Antiviral and Antifungal Agents.

Alternaria / drug effects Antifungal Agents / chemical synthesis Antiviral Agents / chemical synthesis Ascomycota / drug effects Cysteine / chemical synthesis Drug Discovery Microbial Sensitivity Tests Molecular Structure Tobacco Mosaic Virus / drug effects
anti-TMV activity antifungal activity cysteine and its derivatives mode of action molecular docking natural product

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
13 Jan 2021
Historique:
received: 23 12 2020
revised: 07 01 2021
accepted: 11 01 2021
entrez: 16 1 2021
pubmed: 17 1 2021
medline: 8 9 2021
Statut: epublish

Résumé

Based on the structure of the natural product cysteine, a series of thiazolidine-4-carboxylic acids were designed and synthesized. All target compounds bearing thiazolidine-4-carboxylic acid were characterized by

Identifiants

DOI: 10.3390/molecules26020383 PMID: 33450940 PMC: PMC7828423
pubmed: 33450940
pii: molecules26020383
doi: 10.3390/molecules26020383
pmc: PMC7828423
pii:
doi:

Substances chimiques

Antifungal Agents 0
Antiviral Agents 0
Cysteine K848JZ4886

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Natural Science Foundation of Hebei Province
ID : B2020202028

Références

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Auteurs

Shan Yang (S)

School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.

Tienan Wang (T)

School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.

Yanan Zhou (Y)

School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.

Li Shi (L)

School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.

Aidang Lu (A)

School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.

Ziwen Wang (Z)

Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China.
ORCID: 0000-0001-9798-7021

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Deuteromycota › Alternaria › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antifongiques › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Eucaryotes › Champignons › Ascomycota › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés soufrés › Cystéine › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Discovery of Cysteine and Its Derivatives as...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Tobamovirus › Virus de la mosaïque du tabac › Discovery of Cysteine and Its Derivatives as...