Comparison of inspiratory effort with three variable-flow nasal continuous positive airway pressure devices in preterm infants: a cross-over study.
neonatology
physiology
qualitative research
Journal
Archives of disease in childhood. Fetal and neonatal edition
ISSN: 1468-2052
Titre abrégé: Arch Dis Child Fetal Neonatal Ed
Pays: England
ID NLM: 9501297
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
24
08
2020
revised:
25
11
2020
accepted:
08
12
2020
pubmed:
17
1
2021
medline:
30
6
2021
entrez:
16
1
2021
Statut:
ppublish
Résumé
Patient's work of breathing may vary between different neonatal nasal continuous positive airway pressure (NCPAP) devices. Therefore, we aimed to compare the inspiratory effort of three variable-flow NCPAP delivery systems used in preterm infants. Cross-over study. From June 2015 to August 2016, 20 preterm infants weighing ≤2500 g requiring NCPAP for mild respiratory distress syndrome were enrolled. Each patient was successively supported by three randomly assigned variable-flow NCPAP systems (MedinCNO, Infant Flow and Servo-i) for 20 min while maintaining the same continuous positive airway pressure level as the patient was on before the study period. Patients' inspiratory effort was estimated by calculating the sum of the difference between maximal inspiratory and baseline electrical activity of the diaphragm (∆EAdi) for 30 consecutive breaths, and after normalising this obtained value for the timing of the 30 breaths. Physiological parameters (oxygen saturation measured by pulse oximetry, respiratory rate, heart beat, transcutaneous partial pressure CO In a neonatal population of preterm infants, inspiratory effort is comparable between the three tested modern variable-flow NCPAP devices.
Identifiants
pubmed: 33452219
pii: archdischild-2020-320531
doi: 10.1136/archdischild-2020-320531
pmc: PMC8237202
doi:
Substances chimiques
Oxygen
S88TT14065
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
404-407Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Am J Respir Crit Care Med. 2014 Mar 1;189(5):520-31
pubmed: 24467647
Pediatr Crit Care Med. 2019 Jul;20(7):e319-e325
pubmed: 31107378
Pediatr Crit Care Med. 2013 May;14(4):e196-201
pubmed: 23439462
N Engl J Med. 1971 Jun 17;284(24):1333-40
pubmed: 4930602
Respir Care. 2018 Feb;63(2):177-186
pubmed: 29089460
N Engl J Med. 2010 May 27;362(21):1970-9
pubmed: 20472939
Pediatr Pulmonol. 1996 Sep;22(3):188-94
pubmed: 8893258
Arch Dis Child Fetal Neonatal Ed. 2009 Jul;94(4):F245-8
pubmed: 19131432
Crit Care Med. 1988 Dec;16(12):1238-42
pubmed: 3056654
Paediatr Respir Rev. 2011 Sep;12(3):196-205
pubmed: 21722849
Cochrane Database Syst Rev. 2012 Mar 14;(3):CD000510
pubmed: 22419276
J Pediatr. 1976 Jun;88(6):1015-9
pubmed: 775040
Intensive Care Med. 2003 Jul;29(7):1134-40
pubmed: 12774158
Biol Neonate. 1999 Jun;76 Suppl 1:22-8
pubmed: 10393390
Pediatrics. 2001 Sep;108(3):682-5
pubmed: 11533336
Pediatr Crit Care Med. 2012 Mar;13(2):e113-9
pubmed: 21946854
Pediatr Pulmonol. 2003 Sep;36(3):248-52
pubmed: 12910587
Clin Perinatol. 2007 Mar;34(1):73-92, vi
pubmed: 17394931
Pediatrics. 1987 Jan;79(1):26-30
pubmed: 3797169