Maternal depression and childhood injury risk: A population-based cohort study in Denmark.
Adolescent
Child
Delivery of Health Care
Depressive Disorder
Mother-Child Relations
Wounds and Injuries
Journal
Brain and behavior
ISSN: 2162-3279
Titre abrégé: Brain Behav
Pays: United States
ID NLM: 101570837
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
revised:
24
11
2020
received:
01
06
2020
accepted:
23
12
2020
pubmed:
17
1
2021
medline:
1
7
2021
entrez:
16
1
2021
Statut:
ppublish
Résumé
To assess the association between different stages of maternal depression and injury risk in offspring aged 0-10 years. Population-based cohort study of all live-born children in Denmark from 1 January 1997 until 31 December 2013 (n = 1,064,387). Main outcome measure was emergency department contacts with a main diagnosis of injury coded as DS00-DT98 (chapter XIX) according to the ICD-10. All information was obtained from Danish national registries. Maternal depression was associated with higher injury hazard in the offspring throughout childhood compared to offspring of mothers with no history of depression. The strongest association was seen for the first year of life. First-time maternal depression was most strongly associated with injury in the child, especially in the first year of life (aHR = 1.70, 95% CI: 1.48-1.96). Children of mothers with relapse depression had 1.57 higher hazard of injury in the first year of life (aHR: 1.57, 95% CI: 1.44-1.70). Children of mothers with previously treated depression (postdepression) had 1.13 higher hazard of injury in the first year of life (aHR: 1.13, 95% CI: 1.09-1.17). Continuous treatment for depression was associated with a nonsignificant higher hazard of injuries in the first year of life (aHR: 1.06, 95% CI: 0.91-1.23). Maternal depression was associated with higher injury risk in the offspring, particularly in early childhood. The association persisted in children of mothers with relapse depression. Our results suggest that children of mothers with depression are vulnerable several years after depression onset and treatment cessation.
Identifiants
pubmed: 33452760
doi: 10.1002/brb3.2029
pmc: PMC7994683
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e02029Informations de copyright
© 2021 The Authors. Brain and Behavior published by Wiley Periodicals LLC.
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Brain Behav. 2021 Mar;11(3):e02029
pubmed: 33452760