Spectral diffusion analysis of kidney intravoxel incoherent motion MRI in healthy volunteers and patients with renal pathologies.
DWI
IVIM
NNLS
kidney
tubular volume fraction
Journal
Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
20
05
2020
revised:
22
10
2020
accepted:
12
11
2020
pubmed:
20
1
2021
medline:
21
5
2021
entrez:
19
1
2021
Statut:
ppublish
Résumé
To assess the feasibility of measuring tubular and vascular signal fractions in the human kidney using nonnegative least-square (NNLS) analysis of intravoxel incoherent motion data collected in healthy volunteers and patients with renal pathologies. MR imaging was performed at 3 Tesla in 12 healthy subjects and 3 patients with various kidney pathologies (fibrotic kidney disease, failed renal graft, and renal masses). Relative signal fractions f and mean diffusivities of the diffusion components in the cortex, medulla, and renal lesions were obtained using the regularized NNLS fitting of the intravoxel incoherent motion data. Test-retest repeatability of the NNLS approach was tested in 5 volunteers scanned twice. In the healthy kidneys, the NNLS method yielded diffusion spectra with 3 distinguishable components that may be linked to the slow tissue water diffusion, intermediate tubular and vascular flow, and fast blood flow in larger vessels with the relative signal fractions, f NNLS-based intravoxel incoherent motion could potentially become a valuable tool in assessing changes in tubular and vascular volume fractions under pathophysiological conditions.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3085-3095Informations de copyright
© 2021 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.
Références
Le Bihan D, Turner R, Douek P, Patronas N. Diffusion MR imaging: clinical applications. AJR Am J Roentgenol. 1992;159:591-599.
Caroli A, Schneider M, Friedli I, et al. Diffusion-weighted magnetic resonance imaging to assess diffuse renal pathology: a systematic review and statement paper. Nephrol Dial Transplant. 2018;33(suppl 2):ii29-ii40.
Yildirim E, Kirbas I, Teksam M, Karadeli E, Gullu H, Ozer I. Diffusion-weighted MR imaging of kidneys in renal artery stenosis. Eur J Radiol. 2008;65:148-153.
Woo S, Suh CH, Kim SY, Cho JY, Kim SH. Diagnostic performance of DWI for differentiating high- from low-grade clear cell renal cell carcinoma: a systematic review and meta-analysis. AJR Am J Roentgenol. 2017 ;209:W374-W381.
Wang F, Takahashi K, Li H, et al. Assessment of unilateral ureter obstruction with multi-parametric MRI. Magn Reson Med. 2018;79:2216-2227.
Thoeny HC, De Keyzer F, Oyen RH, Peeters RR. Diffusion-weighted MR imaging of kidneys in healthy volunteers and patients with parenchymal diseases: initial experience. Radiology. 2005;235:911-917.
Eisenberger U, Thoeny HC, Binser T, et al. Evaluation of renal allograft function early after transplantation with diffusion-weighted MR imaging. Eur Radiol. 2010;20:1374-1383.
Le Bihan D. Intravoxel incoherent motion perfusion MR imaging: a wake-up call. Radiology. 2008;249:748-752.
Luciani A, Vignaud A, Cavet M, et al. Liver cirrhosis: intravoxel incoherent motion MR imaging-pilot study. Radiology. 2008;249:891-899.
Yamada I, Aung W, Himeno Y, Nakagawa T, Shibuya H. Diffusion coefficients in abdominal organs and hepatic lesions: evaluation with intravoxel incoherent motion echo-planar MR imaging. Radiology. 1999;210:617-623.
Bane O, Wagner M, Zhang JL, et al. Assessment of renal function using intravoxel incoherent motion diffusion-weighted imaging and dynamic contrast-enhanced. J Magn Reson Imaging. 2016;44:317-326.
Wittsack H-J, Lanzman RS, Mathys C, Janssen H, Mödder U, Blondin D. Statistical evaluation of diffusion-weighted imaging of the human kidney. Magn Reson Med. 2010;64:616-622.
Heusch P, Wittsack H-J, Pentang G, et al. Biexponential analysis of diffusion- weighted imaging: comparison of three different calculation methods in transplanted kidneys. Acta Radiol. 2013;54:1210-1217.
Baalen S, Leemans A, Dik P, Lilien MR, Haken B, Froeling M. Intravoxel incoherent motion modeling in the kidneys: comparison of mono-, bi-, and triexponential fit. J Magn Reson Imaging. 2017;46:228-239.
Van der Bel R, Gurney-Champion OJ, Froeling M, Stroes ESG, Nederveen AJ, Krediet CTP. A tri-exponential model for intravoxel incoherent motion analysis of the human kidney: in silico and during pharmacological renal perfusion modulation. Eur J Radiol. 2017;91:168-174.
Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. 1986;161:401-407.
Ichikawa S, Motosugi U, Ichikawa T, Sano K, Morisaka H, Araki T. Intravoxel incoherent motion imaging of the kidney: alterations in diffusion and perfusion in patients with renal dysfunction. Magn Reson Imaging. 2013;31:414-417.
Gurney-Champion OJ, Froeling M, Klaassen R, et al. Minimizing the acquisition time for intravoxel incoherent motion magnetic resonance imaging acquisitions in the liver and pancreas. Invest Radiol. 2016;51:211-220.
Lawson CL, Hanson RJ. Solving Least Squares Problems. Englewood Cliffs, NJ: Prentice-Hall; 1974.
Marchand AJ, Hitti E, Monge F, et al. MRI quantification of diffusion and perfusion in bone marrow by intravoxel incoherent motion (IVIM) and non-negative least square (NNLS) analysis. Magn Reson Imaging. 2014;32:1091-1096.
Wurnig MC, Germann M, Boss A. Is there evidence for more than two diffusion components in abdominal organs? - A magnetic resonance imaging study in healthy volunteers. NMR Biomed. 2018;31:e3852.
Wong SM, Backes WH, Drenthen GS, et al. Spectral diffusion analysis of intravoxel incoherent motion MRI in cerebral small vessel disease. J Magn Reson Imaging. 2020;51:1170-1180.
Whittall KP, MacKay AL. Quantitative interpretation of NMR relaxation data. J Magn Reson. 1989;84:134-156.
Bjarnason TA, Mitchell JR. AnalyzeNNLS: magnetic resonance multiexponential decay image analysis. J Magn Reson. 2010;206:200-204.
Niendorf T, Flemming B, Evans RG, Seeliger E. What do BOLD MR imaging changes in donors’ remaining kidneys tell us? Radiology. 2016;281:653-655.
Knepper MA, Danielson RA, Saidel GM, Post RS. Quantitative analysis of renal medullary anatomy in rats and rabbits. Kidney Int. 1977;12:313-323.
Periquito J, Ku M-C, Cantow K, et al. Unbiased MRI assessment of renal tubular volume fraction with data-driven IVIM. Proceedings of the 27th Annual Meeting of ISMRM, Montréal, Canada, 2019. Abstract 1202.
Fioretto P, Sutherland DER, Najafian B, Mauer M. Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients. Kidney Int. 2006;69:907-912.
Hutchison CA, Batuman V, Behrens J, et al. The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol. 2011;8:43-51.
Schelling JR. Tubular atrophy in the pathogenesis of chronic kidney disease progression. Pediatr Nephrol. 2016;31:693-706.
Mengel M. Deconstructing interstitial fibrosis and tubular atrophy: a step toward precision medicine in renal transplantation. Kidney Int. 2017;92:553-555.
Hommos MS, Rule AD. Should we always defer treatment of kidney disease when there is extensive interstitial fibrosis on biopsy? Am J Nephrol. 2016;44:286-288.
Ljimani A, Caroli A, Laustsen C, et al. Consensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI. MAGMA. 2020;33:177-195.
Finsterbusch J. Improving the performance of diffusion-weighted inner field-of-view echo-planar imaging based on 2D-selective radiofrequency excitations by tilting the excitation plane. J Magn Reson Imag. 2011;35:984-992.
Bjarnason TA, McCreary CR, Dunn JF, Mitchell JR. Quantitative T2 analysis: the effects of noise, regularization, and multivoxel approaches. Magn Reson Med. 2010;63:212-217.
Jerome NP, d'Arcy JA, Feiweier T, et al. Extended T2-IVIM model for correction of TE dependence of pseudo-diffusion volume fraction in clinical diffusion-weighted magnetic resonance imaging. Phys Med Biol. 2016;61:N667-N680.
Rankin AJ, Allwood-Spiers S, Lee MMY, et al. Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients. MAGMA. 2020;33:103-112.
Lin N, Deng J, Zhang L, et al. Targeted single-shot methods for diffusion-weighted imaging in the kidneys. J Magn Reson Imaging. 2011;33:1517-1525.
Yushkevich PA, Piven J, Hazlett HC, et al. User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability. Neuroimage. 2006;31:1116-1128.
Hyslop NP, White WH. Estimating precision using duplicate measurements. J Air Waste Manag Assoc. 2009;59:1032-1039.
Lemke A, Stieltjes B, Schad LR, Laun FB. Toward an optimal distribution of b values for intravoxel incoherent motion imaging. Magn Reson Imaging. 2011;29:766-776.
Zhang JL, Sigmund EE, Rusinek H, et al. Optimization of b-value sampling for diffusion-weighted imaging of the kidney. Magn Reson Med. 2012;67:89-97.
Chevallier O, Zhou N, Cercueil J-P, et al. Comparison of tri-exponential decay vs. bi-exponential decay and full fitting vs. segmented fitting for modeling liver intravoxel incoherent motion diffusion. NMR Biomed. 2019;32:e4155.
Le Bihan D, Breton E, Lallemand D, Aubin ML, Vignaud J, Laval-Jeantet M. Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology. 1988;168:497-505.
Hayashi T, Miyati T, Takahashi J, et al. Diffusion analysis with triexponential function in liver cirrhosis. J Magn Reson Imaging. 2013;38:148-153.
Cercueil JP, Petit JM, Nougaret S, et al. Intravoxel incoherent motion diffusion-weighted imaging in the liver: comparison of mono-, bi- and tri-exponential modelling at 3.0-T. Eur Radiol. 2015;25:1541-1550.
Ueda Y, Takahashi S, Ohno N, et al. Triexponential function analysis of diffusion- weighted MRI for diagnosing prostate cancer. J Magn Reson Imaging. 2016;43:138-148.
Müller MF, Prasad PV, Edelman RR. Can the IVIM model be used for renal perfusion imaging? Eur J Radiol. 1998;26:297-303.
Kennedy-Lydon TM, Crawford C, Wildman SSP, Peppiatt-Wildman CM. Renal pericytes: regulators of medullary blood flow. Acta Physiol (Oxf). 2013;207:212-225.
Leung G, Kirpalani A, Szeto SG, et al. Could MRI be used to image kidney fibrosis? A review of recent advances and remaining barriers. Clin J Am Soc Nephrol. 2017;12:1019-1028.
Morrell GR, Zhang JL, Lee VS. Magnetic resonance imaging of the fibrotic kidney. J Am Soc Nephrol. 2017;28:2564-2570.
Wu H-H, Jia H-R, Zhang Y, Liu L, Xu D-B, Sun H-R. Monitoring the progression of renal fibrosis by T2-weighted signal intensity and diffusion weighted magnetic resonance imaging in cisplatin induced rat models. Chin Med J (Engl). 2015;128:626-631.
Steiger P, Barbieri S, Kruse A, Ith M, Thoeny HC. Selection for biopsy of kidney transplant patients by diffusion-weighted MRI. Eur Radiol. 2017;27:4336-4344.
Le Bihan D, Iima M. Diffusion magnetic resonance imaging: what water tells us about biological tissues. PLoS Biol. 2015;13:e1002246.
Baalen S, Froeling M, Asselman M, et al. Mono, bi- and tri-exponential diffusion MRI modelling for renal solid masses and comparison with histopathological findings. Cancer Imaging. 2018;18:44.
Chandarana H, Kang SK, Wong S, et al. Diffusion-weighted intravoxel incoherent motion imaging of renal tumors with histopathologic correlation. Invest Radiol. 2012;47:688-696.
Gurney-Champion OJ, Rauh SS, Harrington K, Oelfke U, Laun FB, Wetscherek A. Optimal acquisition scheme for flow-compensated intravoxel incoherent motion diffusion-weighted imaging in the abdomen: an accurate and precise clinically feasible protocol. Magn Reson Med. 2020;83:1003-1015.
Morita S, Ueno E, Suzuki K, et al. Navigator-triggered prospective acquisition correction (PACE) technique vs. conventional respiratory-triggered technique for free-breathing 3D MRCP: an initial prospective comparative study using healthy volunteers. J Magn Reson Imaging. 2008;28:673-677.
Müller MF, Prasad PV, Bimmler D, Kaiser A, Edelman RR. Functional imaging of the kidney by means of measurement of the apparent diffusion coefficient. Radiology. 1994;193:711-715.