Biologically active polysaccharide from edible mushrooms: A review.
Agaricales
/ chemistry
Anti-Infective Agents
/ chemistry
Antineoplastic Agents
/ chemistry
Antioxidants
/ chemistry
B-Lymphocytes
/ drug effects
Carbohydrate Sequence
Communicable Diseases
/ drug therapy
Fruiting Bodies, Fungal
/ chemistry
Fungal Polysaccharides
/ chemistry
Gene Expression
Humans
Immunologic Factors
/ chemistry
Killer Cells, Natural
/ drug effects
Lectins, C-Type
/ genetics
Macrophages
/ drug effects
Neoplasms
/ drug therapy
T-Lymphocytes
/ drug effects
Toll-Like Receptor 2
/ genetics
Bioactivities
Edible mushrooms
Polysaccharides
Structure
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
01 Mar 2021
01 Mar 2021
Historique:
received:
15
04
2020
revised:
16
11
2020
accepted:
12
01
2021
pubmed:
20
1
2021
medline:
30
4
2021
entrez:
19
1
2021
Statut:
ppublish
Résumé
Mushrooms are renewable natural gift for humankind, furnished with unique taste, flavor and medicinal properties. For the last few decades study of mushroom polysaccharides has become a matter of great interest to the researchers for their immunomodulating, antimicrobial, antioxidant, anticancer, and antitumor properties. Molecular mass, branching configuration, conformation of polysaccharides and chemical modification are the major factors influencing their biological activities. The mechanism of action of mushroom polysaccharides is to stimulate T-cells, B-cells, natural killer cells, and macrophage dependent immune responses via binding to receptors like the toll-like receptor-2, dectin-1. The present review offers summarized and significant information about the structural and biological properties of mushroom polysaccharides, and their potential for development of therapeutic materials.
Identifiants
pubmed: 33465360
pii: S0141-8130(21)00107-0
doi: 10.1016/j.ijbiomac.2021.01.081
pii:
doi:
Substances chimiques
Anti-Infective Agents
0
Antineoplastic Agents
0
Antioxidants
0
CLEC7A protein, human
0
Fungal Polysaccharides
0
Immunologic Factors
0
Lectins, C-Type
0
TLR2 protein, human
0
Toll-Like Receptor 2
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
408-417Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.