Application of lung substitute material as ripple filter for multi-ion therapy with helium-, carbon-, oxygen-, and neon-ion beams.
charged particle therapy
ripple filter
treatment planning
Journal
Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220
Informations de publication
Date de publication:
12 02 2021
12 02 2021
Historique:
received:
24
11
2020
accepted:
21
01
2021
pubmed:
22
1
2021
medline:
26
3
2022
entrez:
21
1
2021
Statut:
epublish
Résumé
A development project for hypo-fractionated multi-ion therapy has been initiated at the National Institute of Radiological Sciences in Japan. In the treatment, helium, carbon, oxygen, and neon ions will be used as primary beams with pencil beam scanning. A ripple filter (RiFi), consisting of a thin plastic or aluminum plate with a fine periodic ridge and groove structure, has been used to broaden the Bragg peak of heavy-ion beams in the beam direction. To sufficiently broaden the Bragg peak of helium-, carbon-, oxygen-, and neon-ion beams with suppressed lateral scattering and surface dose inhomogeneity, in this study, we tested a plate made of a lung substitute material, Gammex LN300, as the RiFi. The planar integrated dose distribution of a 183.5 MeV u
Identifiants
pubmed: 33477116
doi: 10.1088/1361-6560/abde99
doi:
Substances chimiques
Water
059QF0KO0R
Helium
206GF3GB41
Neon
4VB4Y46AHD
Carbon
7440-44-0
Oxygen
S88TT14065
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2021 Institute of Physics and Engineering in Medicine.