Litter Size of Sheep (
ROH
fecundity
inbreeding
lambing number
sheep
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
18 01 2021
18 01 2021
Historique:
received:
31
12
2020
revised:
14
01
2021
accepted:
15
01
2021
entrez:
22
1
2021
pubmed:
23
1
2021
medline:
22
7
2021
Statut:
epublish
Résumé
Ovine litter size (LS) is an important trait showing variability within breeds. It remains largely unknown whether inbreeding depression on LS exists based on genomic homozygous regions, and whether the homozygous regions resulted from inbreeding are significantly associated with LS in sheep. We here reanalyze a set of single nucleotide polymorphism (SNP) chip of six breeds to characterize the patterns of runs of homozygosity (ROH), to evaluate inbreeding levels and inbreeding depressions on LS, and to identify candidate homozygous regions responsible for LS. Consequently, unique ROH patterns were observed among six sheep populations. Inbreeding depression on LS was only found in Hu sheep, where a significant reduction of 0.016, 0.02, and 0.02 per 1% elevated inbreeding F
Identifiants
pubmed: 33477586
pii: genes12010109
doi: 10.3390/genes12010109
pmc: PMC7831309
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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