Managing opioid withdrawal precipitated by buprenorphine with buprenorphine.
buprenorphine
opioid dependence
opioid withdrawal
precipitated withdrawal
treatment
Journal
Drug and alcohol review
ISSN: 1465-3362
Titre abrégé: Drug Alcohol Rev
Pays: Australia
ID NLM: 9015440
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
revised:
21
09
2020
received:
04
02
2020
accepted:
10
11
2020
pubmed:
23
1
2021
medline:
27
11
2021
entrez:
22
1
2021
Statut:
ppublish
Résumé
Buprenorphine is a partial opioid agonist commonly used to treat opioid dependence. The pharmacology of buprenorphine increases the risk of a precipitated opioid withdrawal when commencing patients on buprenorphine treatment, particularly when transferring from long acting opioids (e.g. methadone). There is little documented experience regarding the management of precipitated withdrawal. In our case, a patient developed a significant precipitated opioid withdrawal following buprenorphine administration, and was able to be successfully treated in hospital with further buprenorphine. This demonstrates that rapid increases in buprenorphine dose can be used as an effective treatment for buprenorphine-induced precipitated opioid withdrawal. The use of buprenorphine to manage withdrawal then allows the individual to continue on this highly effective treatment.
Identifiants
pubmed: 33480051
doi: 10.1111/dar.13228
pmc: PMC8248003
doi:
Substances chimiques
Analgesics, Opioid
0
Narcotic Antagonists
0
Buprenorphine
40D3SCR4GZ
Methadone
UC6VBE7V1Z
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
567-571Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2021 The Authors. Drug and Alcohol Review published by John Wiley & Sons Australia, Ltd on behalf of Australasian Professional Society on Alcohol and other Drugs.
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