Use of diuretics in the neonatal period.
AKI
Bronchopulmonary dysplasia
Diuretics
Furosemide
NICU
Neonates
VLBW
Journal
Pediatric nephrology (Berlin, Germany)
ISSN: 1432-198X
Titre abrégé: Pediatr Nephrol
Pays: Germany
ID NLM: 8708728
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
02
10
2020
accepted:
05
01
2021
revised:
06
11
2020
pubmed:
23
1
2021
medline:
4
3
2022
entrez:
22
1
2021
Statut:
ppublish
Résumé
The use of diuretics is extremely frequent in sick neonates, the more so in very premature newborn infants. The use of diuretics in patients whose kidney function is immature necessitates a thorough knowledge of renal developmental physiology and pathophysiology. This review presents the basic aspects of body fluid homeostasis in the neonate, discusses the development of kidney function, and describes the mechanisms involved in electrolyte and water reabsorption along the nephron. Diuretics are then classified according to the site of their action on sodium reabsorption. The use of diuretics in sodium-retaining states, in oliguric states, in electrolyte disorders, and in arterial hypertension, as well as in a few specific disorders, is presented. Common and specific adverse effects are discussed. Recommended dosages for the main diuretics used in the neonatal period are given. New developments in diuretic therapy are briefly mentioned.
Identifiants
pubmed: 33481099
doi: 10.1007/s00467-021-04921-3
pii: 10.1007/s00467-021-04921-3
doi:
Substances chimiques
Diuretics
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2687-2695Informations de copyright
© 2021. IPNA.
Références
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