Use of intravenous lidocaine to treat dexmedetomidine-induced bradycardia in sedated and anesthetized dogs.


Journal

Veterinary anaesthesia and analgesia
ISSN: 1467-2995
Titre abrégé: Vet Anaesth Analg
Pays: United States
ID NLM: 100956422

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 17 08 2020
revised: 18 11 2020
accepted: 21 11 2020
pubmed: 25 1 2021
medline: 25 11 2021
entrez: 24 1 2021
Statut: ppublish

Résumé

To assess cardiopulmonary function in sedated and anesthetized dogs administered intravenous (IV) dexmedetomidine and subsequently administered IV lidocaine to treat dexmedetomidine-induced bradycardia. Prospective, randomized, crossover experimental trial. A total of six purpose-bred female Beagle dogs, weighing 9.1 ± 0.6 kg (mean ± standard deviation). Dogs were randomly assigned to one of three treatments: dexmedetomidine (10 μg kg When administered after a bolus of dexmedetomidine, lidocaine bolus and L-CRI significantly increased heart rate and cardiac index, decreased mean blood pressure, systemic vascular resistance index and oxygen extraction ratio, and did not affect stroke volume index in all treatments. Lidocaine was an effective treatment for dexmedetomidine-induced bradycardia in healthy research dogs.

Identifiants

pubmed: 33485784
pii: S1467-2987(20)30279-8
doi: 10.1016/j.vaa.2020.11.005
pii:
doi:

Substances chimiques

Anesthetics, Inhalation 0
Dexmedetomidine 67VB76HONO
Lidocaine 98PI200987
Isoflurane CYS9AKD70P

Types de publication

Journal Article Randomized Controlled Trial, Veterinary

Langues

eng

Sous-ensembles de citation

IM

Pagination

174-186

Informations de copyright

Copyright © 2020 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.

Auteurs

Tainor Tisotti (T)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Alexander Valverde (A)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada. Electronic address: valverde@uoguelph.ca.

Ashley Hopkins (A)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

M Lynne O'Sullivan (ML)

Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, PE, Canada.

Brad Hanna (B)

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Luis Arroyo (L)

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

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Classifications MeSH