Topographical analysis of structural lesions between dominant and non-dominant hands in erosive osteoarthritis.


Journal

Rheumatology international
ISSN: 1437-160X
Titre abrégé: Rheumatol Int
Pays: Germany
ID NLM: 8206885

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 11 11 2020
accepted: 30 12 2020
pubmed: 28 1 2021
medline: 16 11 2021
entrez: 27 1 2021
Statut: ppublish

Résumé

No difference between both hands was observed for clinical and radiographical presentations in EHOA patients. A bilateral and symmetrical relationship was found between hand joints. EHOA have symmetrical distribution and specific association in structural lesions. This study aims to analyse the preferential topographical distribution of clinical and structural lesions between the dominant and non-dominant hands in erosive hand osteoarthritis (EHOA) patients. Both hands were assessed via radiography in EHOA patients. A comparative analysis of the clinical features and structural lesions between the dominant and non-dominant hands was performed. The structural lesions were assessed according to the anatomical radiographic score of Verbruggen-Veys (VV). Next, a principal component analysis was performed to describe and highlight the relationships observed between the joints. Sixty patients were included in this study: there were 57 women, and the mean age was 66.1 (± 7.6) years. For the distal interphalangeal (DIP) joints, nodes were observed more frequently on the dominant hand (4 vs 3; p = 0.005). No difference in structural lesions was observed between the two hands except for the 2nd proximal interphalangeal (PIP) (p = 0.045). A principal component analysis with varimax rotation described relationships between the 2nd PIP, 3rd PIP, 4th PIP, 4th DIP and 5th DIP joints in both hands. No significant differences between dominant and non-dominant hands were observed for clinical and structural lesions in our sample of EHOA patients. A bilateral and symmetrical injury was observed in most EHOA joints. Trial registration Clinical trial registration number: NCT01068405.

Identifiants

pubmed: 33501510
doi: 10.1007/s00296-020-04784-1
pii: 10.1007/s00296-020-04784-1
doi:

Banques de données

ClinicalTrials.gov
['NCT01068405']

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

617-623

Références

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Auteurs

Edem Allado (E)

Department Rheumatology, Université de Lorraine, CHRU-Nancy, 54000, Nancy, France. e.allado@chru-nancy.fr.
University Center of Sports Medicine and Adapted Physical Activity, Université de Lorraine, CHRU-Nancy, 54000, Nancy, France. e.allado@chru-nancy.fr.
Université de Lorraine, 54000, Nancy, DevAH, France. e.allado@chru-nancy.fr.

Ruth Wittoek (R)

Department of Rheumatology, Faculty of Medicine and Health Sciences, Laboratory for Molecular Immunology and Inflammation, Ghent University, C. Heymanslaan 10, 9000, Ghent, Belgium.

Eliane Albuisson (E)

Université de Lorraine, 54000, Nancy, InSciDenS, France.
Université de Lorraine, CNRS, IECL, 54000, Nancy, France.

Stephanie Ferrero (S)

Department Rheumatology, University of Cote D'Azur, Nice Hospital, Nice, France.

Bruno Chenuel (B)

University Center of Sports Medicine and Adapted Physical Activity, Université de Lorraine, CHRU-Nancy, 54000, Nancy, France.
Université de Lorraine, 54000, Nancy, DevAH, France.

Isabelle Chary-Valckenaere (I)

Department Rheumatology, Université de Lorraine, CHRU-Nancy, 54000, Nancy, France.
Université de Lorraine, 54000, Nancy, IMoPA, France.

Christian Roux (C)

Department Rheumatology, University of Cote D'Azur, Nice Hospital, Nice, France.

Damien Loeuille (D)

Department Rheumatology, Université de Lorraine, CHRU-Nancy, 54000, Nancy, France.
Université de Lorraine, 54000, Nancy, IMoPA, France.

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