Prosthesis-patient mismatch is an independent predictor of congestive heart failure after transcatheter aortic valve replacement.
Aged
Aged, 80 and over
Aortic Valve
/ physiopathology
Aortic Valve Insufficiency
/ etiology
Aortic Valve Stenosis
/ mortality
Female
Heart Failure
/ etiology
Heart Valve Prosthesis
Humans
Male
Prosthesis Design
Retrospective Studies
Risk Assessment
Risk Factors
Severity of Illness Index
Time Factors
Transcatheter Aortic Valve Replacement
/ adverse effects
Treatment Outcome
Aortic stenosis
Congestive heart failure
Insuffisance cardiaque
Mismatch patient prothèse
Patient-prosthesis mismatch
SAPIEN 3
Sténose aortique
TAVI
TAVR
Journal
Archives of cardiovascular diseases
ISSN: 1875-2128
Titre abrégé: Arch Cardiovasc Dis
Pays: Netherlands
ID NLM: 101465655
Informations de publication
Date de publication:
Historique:
received:
28
04
2020
revised:
15
07
2020
accepted:
17
11
2020
pubmed:
30
1
2021
medline:
3
9
2021
entrez:
29
1
2021
Statut:
ppublish
Résumé
Little is known about the effect of prosthesis-patient mismatch (PPM) on outcomes after transcatheter aortic valve replacement. We reported previously an increased risk of PPM with the SAPIEN 3 transcatheter heart valve (S3-THV). To investigate the association of PPM with 1-year outcomes in patients with severe aortic stenosis (AS) implanted with S3-THV. Moderate PPM was defined by an indexed effective orifice area (iEOA)≤0.85cm A total of 208 consecutive patients were included between 2016 and 2018. Male sex was prevalent (53.8%), mean age was 81.9±6.2 years, mean EuroSCORE II was 4.35±3.37, mean LVEF was 57.9±13%. Moderate and severe PPM were observed in 69 (33.2%) and 10 (4.8%) patients. Patients with PPM were younger (80.4±7 vs 82.8±5.41 years; P=0.006), had a larger BSA (1.84±0.19 vs 1.77±0.19 m PPM after S3-THV implantation is strongly associated with CHF at 1 year, but is not correlated with overall mortality.
Sections du résumé
BACKGROUND
BACKGROUND
Little is known about the effect of prosthesis-patient mismatch (PPM) on outcomes after transcatheter aortic valve replacement. We reported previously an increased risk of PPM with the SAPIEN 3 transcatheter heart valve (S3-THV).
AIMS
OBJECTIVE
To investigate the association of PPM with 1-year outcomes in patients with severe aortic stenosis (AS) implanted with S3-THV.
METHODS
METHODS
Moderate PPM was defined by an indexed effective orifice area (iEOA)≤0.85cm
RESULTS
RESULTS
A total of 208 consecutive patients were included between 2016 and 2018. Male sex was prevalent (53.8%), mean age was 81.9±6.2 years, mean EuroSCORE II was 4.35±3.37, mean LVEF was 57.9±13%. Moderate and severe PPM were observed in 69 (33.2%) and 10 (4.8%) patients. Patients with PPM were younger (80.4±7 vs 82.8±5.41 years; P=0.006), had a larger BSA (1.84±0.19 vs 1.77±0.19 m
CONCLUSIONS
CONCLUSIONS
PPM after S3-THV implantation is strongly associated with CHF at 1 year, but is not correlated with overall mortality.
Identifiants
pubmed: 33509746
pii: S1875-2136(21)00003-6
doi: 10.1016/j.acvd.2020.11.005
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
504-514Informations de copyright
Copyright © 2021 Elsevier Masson SAS. All rights reserved.