[Structured implementation and high adherence to the ERAS program in colorectal surgery in two operating units of the ASUR Marche.]

Implementazione strutturata ed elevata aderenza al programma ERAS in chirurgia colorettale in due unità operative dell’ASUR Marche.

Journal

Recenti progressi in medicina
ISSN: 2038-1840
Titre abrégé: Recenti Prog Med
Pays: Italy
ID NLM: 0401271

Informations de publication

Date de publication:
01 2021
Historique:
entrez: 29 1 2021
pubmed: 30 1 2021
medline: 13 4 2022
Statut: ppublish

Résumé

An Enhanced Recovery After Surgery (ERAS) program in colorectal surgery is able to significantly reduce the morbidity rates and postoperative hospital stay (LOS) related to the intervention. However, it is not clear what modalities and levels of implementation are necessary to achieve these results. The purpose of this work is to analyze the methods and results of the first year of implementation of the program in two centers of the Agenzia Sanitaria Unica Regionale (ASUR) Marche. After a structured implementation pathway, characterized by the creation of a core team, field training, internal courses and coaching, the details of 196 consecutive cases of patients submitted to colorectal resection over a one-year period in two surgical units of the ASUR Marche were prospectively loaded in a database, considering over 50 variables including adherence to the individual items of the ERAS program. The primary outcomes were: overall and major morbidity, mortality and anastomotic dehiscence rates; secondary outcomes were: LOS, re-admission and re-intervention rates. The results of primary endpoints were evaluated by univariable and multivariable analyses with logistic regression and, thereafter, according to ERAS item adherence rate. After a median (interquartile range, IQR) follow-up of 40 (32-94) days, we recorded complications in 72 patients (overall morbidity 36.7%), major morbidity in 14 patients (7.1%), 6 deaths (mortality 3.1%), an anastomotic dehiscence in 9 cases (4.9%), median (IQR) overalll LOS 5 (3-7) days, 10 readmissions (5.1%) and 13 reoperations (6.7%). The mean adherence rate to the items of the ERAS program was 85.4%, showing a significant dose-effect curve for overall morbidity, major morbidity, anastomotic leakage and for overall LOS. The ERAS implementation methods in this project led to a high adherence (>80%) to the program items. All the results showed a significant improvement compared to the previous pre-implementation period and according to the adherence to program items rate.

Sections du résumé

BACKGROUND
An Enhanced Recovery After Surgery (ERAS) program in colorectal surgery is able to significantly reduce the morbidity rates and postoperative hospital stay (LOS) related to the intervention. However, it is not clear what modalities and levels of implementation are necessary to achieve these results. The purpose of this work is to analyze the methods and results of the first year of implementation of the program in two centers of the Agenzia Sanitaria Unica Regionale (ASUR) Marche.
MATERIALS
After a structured implementation pathway, characterized by the creation of a core team, field training, internal courses and coaching, the details of 196 consecutive cases of patients submitted to colorectal resection over a one-year period in two surgical units of the ASUR Marche were prospectively loaded in a database, considering over 50 variables including adherence to the individual items of the ERAS program. The primary outcomes were: overall and major morbidity, mortality and anastomotic dehiscence rates; secondary outcomes were: LOS, re-admission and re-intervention rates. The results of primary endpoints were evaluated by univariable and multivariable analyses with logistic regression and, thereafter, according to ERAS item adherence rate.
RESULTS
After a median (interquartile range, IQR) follow-up of 40 (32-94) days, we recorded complications in 72 patients (overall morbidity 36.7%), major morbidity in 14 patients (7.1%), 6 deaths (mortality 3.1%), an anastomotic dehiscence in 9 cases (4.9%), median (IQR) overalll LOS 5 (3-7) days, 10 readmissions (5.1%) and 13 reoperations (6.7%). The mean adherence rate to the items of the ERAS program was 85.4%, showing a significant dose-effect curve for overall morbidity, major morbidity, anastomotic leakage and for overall LOS.
DISCUSSION
The ERAS implementation methods in this project led to a high adherence (>80%) to the program items. All the results showed a significant improvement compared to the previous pre-implementation period and according to the adherence to program items rate.

Identifiants

pubmed: 33512357
doi: 10.1701/3525.35122
doi:

Types de publication

Journal Article

Langues

ita

Sous-ensembles de citation

IM

Pagination

30-44

Auteurs

Marco Catarci (M)

UOC Chirurgia Generale, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Angela Maurizi (A)

UOC Chirurgia Generale, Ospedale C. Urbani, Jesi (AN), Area Vasta 2.

Michele Benedetti (M)

UOC Chirurgia Generale, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Antonella Giachetta (A)

UOC Chirurgia Generale, Ospedale C. Urbani, Jesi (AN), Area Vasta 2.

Simona Ciotti (S)

UOC Chirurgia Generale, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Francesco Spinelli (F)

UOC Anestesia e Rianimazione, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Tonino Bernacconi (T)

UOC Anestesia e Rianimazione, Ospedale C. Urbani, Jesi (AN), Area Vasta 2.

Barbara Gionni (B)

UOC Chirurgia Generale, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Luca Astolfi (L)

UOC Anestesia e Rianimazione, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Claudia Paoletti (C)

UOC Anestesia e Rianimazione, Ospedale C. Urbani, Jesi (AN), Area Vasta 2.

Giorgio Forlini (G)

UOC Anestesia e Rianimazione, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Silvia Marzocchini (S)

UOC Anestesia e Rianimazione, Ospedale C. Urbani, Jesi (AN), Area Vasta 2.

Giovanna Casuale (G)

UOC Chirurgia Generale, Ospedale C. Urbani, Jesi (AN), Area Vasta 2.

Maria Valeria Valeri (MV)

Servizio Dietologia, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Nicoletta Clementi (N)

Servizio Dietologia, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Simone Cicconi (S)

UOC Chirurgia Generale, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Irene Marziali (I)

UOC Chirurgia Generale, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Gianluca Guercioni (G)

UOC Chirurgia Generale, Ospedale C. e G. Mazzoni, Ascoli Piceno, Area Vasta 5.

Roberto Campagnacci (R)

UOC Chirurgia Generale, Ospedale C. Urbani, Jesi (AN), Area Vasta 2.

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