The First Case of Eosinophilic Granulomatosis with Polyangiitis Simultaneously Demonstrating Various Clinical Manifestations with Retroperitoneal Fibrosis and Membranous Nephropathy.


Journal

Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241

Informations de publication

Date de publication:
15 Jun 2021
Historique:
pubmed: 2 2 2021
medline: 22 6 2021
entrez: 1 2 2021
Statut: ppublish

Résumé

The first case of eosinophilic granulomatosis with polyangiitis (EGPA) simultaneously demonstrating various clinical manifestations, including retroperitoneal fibrosis (RPF) causing hydronephrosis and membranous nephropathy (MN) leading to nephrotic syndrome, is presented. There have been no previous case reports demonstrating the simultaneous onset of these three disease categories with significant complex pathologies. This case was successfully managed by providing adequate combination therapies according to each disease category, leading to complete remission (CR) of all three diseases. In conclusion, we believe this case is extremely rare and clinically suggestive, and that these findings can be applied to a future phenotype-tailored treatment strategy for EGPA.

Identifiants

pubmed: 33518573
doi: 10.2169/internalmedicine.6399-20
pmc: PMC8263185
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1963-1969

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Auteurs

Isao Kondo (I)

Department of Nephrology, National Center for Global Health and Medicine, Japan.

Yohei Arai (Y)

Department of Nephrology, National Center for Global Health and Medicine, Japan.
Department of Nephrology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.

Emi Sakamoto (E)

Department of Nephrology, National Center for Global Health and Medicine, Japan.

Daisuke Katagiri (D)

Department of Nephrology, National Center for Global Health and Medicine, Japan.

Fumihiko Hinoshita (F)

Department of Nephrology, National Center for Global Health and Medicine, Japan.

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