Cancer surgery during the COVID-19 pandemic: The experience of a comprehensive cancer center performing preoperative screening by RT-PCR and chest CT scan.
Adult
Aged
Aged, 80 and over
Algorithms
COVID-19
/ diagnosis
COVID-19 Nucleic Acid Testing
Cancer Care Facilities
Female
France
Humans
Incidence
Infection Control
/ organization & administration
Male
Middle Aged
Neoplasms
/ complications
Postoperative Complications
/ epidemiology
Predictive Value of Tests
Preoperative Care
Reproducibility of Results
Retrospective Studies
Reverse Transcriptase Polymerase Chain Reaction
Tomography, X-Ray Computed
Young Adult
COVID-19 preoperative screening algorithm
chest CT scan
nasopharyngeal COVID-19 RT-PCR
oncologic procedures
Journal
Journal of surgical oncology
ISSN: 1096-9098
Titre abrégé: J Surg Oncol
Pays: United States
ID NLM: 0222643
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
24
11
2020
revised:
30
11
2020
accepted:
30
11
2020
pubmed:
2
2
2021
medline:
4
3
2021
entrez:
1
2
2021
Statut:
ppublish
Résumé
During the worldwide pandemic of coronavirus disease 2019 (COVID-19), oncological procedures considered to be urgent could not be delayed, and a specific procedure was required to continue surgical activity. The objective was to assess the efficacy of our preoperative screening algorithm. This observational retrospective study was performed between the 25th of March and the 12th of May 2020 in a comprehensive cancer center in France. Patients undergoing elective oncologic surgery were tested by preoperative nasopharyngeal reverse-transcription polymerase chain reaction (RT-PCR) that could be associated with a chest computerized tomography (CT) scan. Of the 510 screening tests (in 477 patients), only 5% (15/477) were positive for COVID-19 in 24 patients (18 RT-PCR+ and 7 CT scan+/RT-PCR-). Four patients were ultimately false positives based on the CT scan. In total, only 4.2% (20/477) of the patients were COVID-19+. The positivity rate decreased with time after the containment measures were implemented (from 7.4% to 0.8%). In the COVID-19+ group, 20% of the patients had postoperative pulmonary complications, whereas this was the case for 5% of the patients in the COVID-19 group. Maintaining secure surgical activity is achievable and paramount in oncology care, even during the COVID-19 pandemic, with appropriate screening based on preoperative RT-PCR.
Sections du résumé
BACKGROUND AND OBJECTIVES
OBJECTIVE
During the worldwide pandemic of coronavirus disease 2019 (COVID-19), oncological procedures considered to be urgent could not be delayed, and a specific procedure was required to continue surgical activity. The objective was to assess the efficacy of our preoperative screening algorithm.
METHODS
METHODS
This observational retrospective study was performed between the 25th of March and the 12th of May 2020 in a comprehensive cancer center in France. Patients undergoing elective oncologic surgery were tested by preoperative nasopharyngeal reverse-transcription polymerase chain reaction (RT-PCR) that could be associated with a chest computerized tomography (CT) scan.
RESULTS
RESULTS
Of the 510 screening tests (in 477 patients), only 5% (15/477) were positive for COVID-19 in 24 patients (18 RT-PCR+ and 7 CT scan+/RT-PCR-). Four patients were ultimately false positives based on the CT scan. In total, only 4.2% (20/477) of the patients were COVID-19+. The positivity rate decreased with time after the containment measures were implemented (from 7.4% to 0.8%). In the COVID-19+ group, 20% of the patients had postoperative pulmonary complications, whereas this was the case for 5% of the patients in the COVID-19 group.
CONCLUSIONS
CONCLUSIONS
Maintaining secure surgical activity is achievable and paramount in oncology care, even during the COVID-19 pandemic, with appropriate screening based on preoperative RT-PCR.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
815-822Informations de copyright
© 2021 Wiley Periodicals LLC.
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