A Compact Multi-Distance DCS and Time Domain NIRS Hybrid System for Hemodynamic and Metabolic Measurements.
diffuse correlation spectroscopy
diffuse optics
time domain near infrared spectroscopy
Journal
Sensors (Basel, Switzerland)
ISSN: 1424-8220
Titre abrégé: Sensors (Basel)
Pays: Switzerland
ID NLM: 101204366
Informations de publication
Date de publication:
28 Jan 2021
28 Jan 2021
Historique:
received:
31
12
2020
revised:
22
01
2021
accepted:
24
01
2021
entrez:
2
2
2021
pubmed:
3
2
2021
medline:
16
4
2021
Statut:
epublish
Résumé
In this work, we present a new multi-distance diffuse correlation spectroscopy (DCS) device integrated with a compact state-of-the-art time domain near infrared spectroscopy (TD-NIRS) device. The hybrid DCS and TD-NIRS system allows to retrieve information on blood flow, tissue oxygenation, and oxygen metabolic rate. The DCS device performances were estimated in terms of stability, repeatability, ability in retrieving variations of diffusion coefficient, influence of the tissue optical properties, effect of varying count rates and depth sensitivity. Crosstalk between DCS and TD-NIRS optical signals was also evaluated. Finally, in vivo experiments (venous and arterial cuff occlusions on the arm) were conducted to test the ability of the hybrid system in measuring blood flow variations.
Identifiants
pubmed: 33525488
pii: s21030870
doi: 10.3390/s21030870
pmc: PMC7866011
pii:
doi:
Substances chimiques
Oxygen
S88TT14065
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Horizon 2020 Framework Programme
ID : 863087
Organisme : Horizon 2020 Research and Innovation
ID : 101016087
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