Relax, Keep Walking - A Practical Guide to Continuous Phylogeographic Inference with BEAST.

BEAST continuous phylogeography relaxed random walk viruses

Journal

Molecular biology and evolution
ISSN: 1537-1719
Titre abrégé: Mol Biol Evol
Pays: United States
ID NLM: 8501455

Informations de publication

Date de publication:
29 07 2021
Historique:
pubmed: 3 2 2021
medline: 21 9 2021
entrez: 2 2 2021
Statut: ppublish

Résumé

Spatially explicit phylogeographic analyses can be performed with an inference framework that employs relaxed random walks to reconstruct phylogenetic dispersal histories in continuous space. This core model was first implemented 10 years ago and has opened up new opportunities in the field of phylodynamics, allowing researchers to map and analyze the spatial dissemination of rapidly evolving pathogens. We here provide a detailed and step-by-step guide on how to set up, run, and interpret continuous phylogeographic analyses using the programs BEAUti, BEAST, Tracer, and TreeAnnotator.

Identifiants

pubmed: 33528560
pii: 6126413
doi: 10.1093/molbev/msab031
pmc: PMC8321535
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3486-3493

Subventions

Organisme : NIAID NIH HHS
ID : U19 AI135995
Pays : United States
Organisme : Wellcome Trust
ID : 204311/Z/16/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S019510/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S0195/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 206298/Z/17/Z
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R015600/1
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : R56 AI149004
Pays : United States

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

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Auteurs

Simon Dellicour (S)

Spatial Epidemiology Lab (SpELL), Université Libre de Bruxelles, Bruxelles, Belgium.
Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.

Mandev S Gill (MS)

Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.

Nuno R Faria (NR)

MRC Centre for Global Infectious Disease Analysis, J-IDEA, Imperial College London, London, United Kingdom.
Department of Zoology, University of Oxford, Oxford, United Kingdom.
Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.

Andrew Rambaut (A)

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom.

Oliver G Pybus (OG)

Department of Zoology, University of Oxford, Oxford, United Kingdom.

Marc A Suchard (MA)

Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA.
Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Philippe Lemey (P)

Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.

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Classifications MeSH