Guideline: Vulvovaginal candidosis (AWMF 015/072, level S2k).
Anti-Bacterial Agents
/ adverse effects
Antifungal Agents
/ therapeutic use
Candida albicans
/ drug effects
Candida glabrata
/ drug effects
Candidiasis, Vulvovaginal
/ diagnosis
Causality
Ciclopirox
/ administration & dosage
Contraceptive Agents
/ administration & dosage
Diabetes Mellitus
Female
Hormones
/ adverse effects
Humans
Hyphae
/ isolation & purification
Imidazoles
/ administration & dosage
Infant, Newborn
Polyenes
/ administration & dosage
Pregnancy
Vaginitis
/ diagnosis
Candida
candidosis
diagnosis
therapy
vulvovaginal candidosis
Journal
Mycoses
ISSN: 1439-0507
Titre abrégé: Mycoses
Pays: Germany
ID NLM: 8805008
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
21
01
2021
accepted:
27
01
2021
pubmed:
3
2
2021
medline:
11
8
2021
entrez:
2
2
2021
Statut:
ppublish
Résumé
Approximately 70-75% of women will have vulvovaginal candidosis (VVC) at least once in their lifetime. In premenopausal, pregnant, asymptomatic and healthy women and women with acute VVC, Candida albicans is the predominant species. The diagnosis of VVC should be based on clinical symptoms and microscopic detection of pseudohyphae. Symptoms alone do not allow reliable differentiation of the causes of vaginitis. In recurrent or complicated cases, diagnostics should involve fungal culture with species identification. Serological determination of antibody titres has no role in VVC. Before the induction of therapy, VVC should always be medically confirmed. Acute VVC can be treated with local imidazoles, polyenes or ciclopirox olamine, using vaginal tablets, ovules or creams. Triazoles can also be prescribed orally, together with antifungal creams, for the treatment of the vulva. Commonly available antimycotics are generally well tolerated, and the different regimens show similarly good results. Antiseptics are potentially effective but act against the physiological vaginal flora. Neither a woman with asymptomatic colonisation nor an asymptomatic sexual partner should be treated. Women with chronic recurrent Candida albicans vulvovaginitis should undergo dose-reducing maintenance therapy with oral triazoles. Unnecessary antimycotic therapies should always be avoided, and non-albicans vaginitis should be treated with alternative antifungal agents. In the last 6 weeks of pregnancy, women should receive antifungal treatment to reduce the risk of vertical transmission, oral thrush and diaper dermatitis of the newborn. Local treatment is preferred during pregnancy.
Identifiants
pubmed: 33529414
doi: 10.1111/myc.13248
pmc: PMC8248160
doi:
Substances chimiques
Anti-Bacterial Agents
0
Antifungal Agents
0
Contraceptive Agents
0
Hormones
0
Imidazoles
0
Polyenes
0
Ciclopirox
19W019ZDRJ
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
583-602Subventions
Organisme : Deutschsprachige Mykologische Gesellschaft (DMykG)
Organisme : Deutsche Gesellschaft fuer Gynaekologie und Geburtshilfe (DGGG)
Informations de copyright
© 2021 The Authors.Mycoses published by Wiley-VCH GmbH.
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