Roles of developmentally regulated KIF2A alternative isoforms in cortical neuron migration and differentiation.
Alternative Splicing
Animals
Cell Differentiation
/ genetics
Cell Movement
/ genetics
Cerebral Cortex
/ cytology
Gene Expression Profiling
Gene Expression Regulation
Kinesins
/ genetics
Mice
Mutation
Neurogenesis
/ genetics
Neurons
/ cytology
Proteomics
/ methods
RNA Isoforms
Repressor Proteins
/ genetics
Alternative splicing
Cortical development
KIF2A
Proximity-interactome mapping
Journal
Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744
Informations de publication
Date de publication:
22 02 2021
22 02 2021
Historique:
received:
08
05
2020
accepted:
18
01
2021
pubmed:
4
2
2021
medline:
3
8
2021
entrez:
3
2
2021
Statut:
epublish
Résumé
KIF2A is a kinesin motor protein with essential roles in neural progenitor division and axonal pruning during brain development. However, how different KIF2A alternative isoforms function during development of the cerebral cortex is not known. Here, we focus on three
Identifiants
pubmed: 33531432
pii: dev.192674
doi: 10.1242/dev.192674
pii:
doi:
Substances chimiques
RNA Isoforms
0
Repressor Proteins
0
KIF2A protein, mouse
EC 3.6.1.-
Kinesins
EC 3.6.4.4
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2021. Published by The Company of Biologists Ltd.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare no competing or financial interests.