A case of recurrent anemia due to chronic parvovirus B19 infection in a kidney transplant recipient. Can everolimus make a difference?
Anemia
Immunoglobulin
Kidney transplantation
Parvovirus B19
mTOR inhibitor
Journal
CEN case reports
ISSN: 2192-4449
Titre abrégé: CEN Case Rep
Pays: Japan
ID NLM: 101636244
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
received:
26
08
2020
accepted:
06
01
2021
pubmed:
5
2
2021
medline:
25
11
2021
entrez:
4
2
2021
Statut:
ppublish
Résumé
Parvovirus B19 (PB19) is a common infection among solid transplant recipients. Usually, it is asymptomatic, but sometimes it can become a real therapeutic challenge. We report a case of a kidney transplant recipient with relapsing pure red cell aplasia due to PB19 infection. Our patient was initially managed with standard treatment consisting of intravenous immunoglobulins and minimization of immunosuppressive treatment. However, when this approach became ineffective, conversion from tacrolimus to everolimus was done, with favorable results. This paper explores infection by PB19 in kidney transplant recipients and the potential benefits of a calcineurin inhibitor-free immunosuppression and the antiviral properties of mTOR inhibitors.
Identifiants
pubmed: 33539009
doi: 10.1007/s13730-021-00575-0
pii: 10.1007/s13730-021-00575-0
pmc: PMC8271085
doi:
Substances chimiques
Everolimus
9HW64Q8G6G
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
388-392Informations de copyright
© 2021. Japanese Society of Nephrology.
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