Antibodies to SARS-CoV-2 protect against re-infection during outbreaks in care homes, September and October 2020.
Adult
Aged
Aged, 80 and over
Antibodies, Viral
/ blood
COVID-19
/ blood
COVID-19 Serological Testing
Disease Outbreaks
/ prevention & control
Female
Humans
London
Male
Middle Aged
Nursing Homes
/ statistics & numerical data
Pandemics
Reinfection
/ prevention & control
Reverse Transcriptase Polymerase Chain Reaction
SARS-CoV-2
/ genetics
Whole Genome Sequencing
COVID-19 outbreak
care homes
Journal
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
entrez:
5
2
2021
pubmed:
6
2
2021
medline:
10
2
2021
Statut:
ppublish
Résumé
Two London care homes experienced a second COVID-19 outbreak, with 29/209 (13.9%) SARS-CoV-2 RT-PCR-positive cases (16/103 residents, 13/106 staff). In those with prior SARS-CoV-2 exposure, 1/88 (1.1%) individuals (antibody positive: 87; RT-PCR-positive: 1) became PCR-positive compared with 22/73 (30.1%) with confirmed seronegative status. After four months protection offered by prior infection against re-infection was 96.2% (95% confidence interval (CI): 72.7-99.5%) using risk ratios from comparison of proportions and 96.1% (95% CI: 78.8-99.3%) using a penalised logistic regression model.
Identifiants
pubmed: 33541486
doi: 10.2807/1560-7917.ES.2021.26.5.2100092
pmc: PMC7863231
doi:
Substances chimiques
Antibodies, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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