High-resolution structural profile of hylaseptin-4: Aggregation, membrane topology and pH dependence of overall membrane binding process.

Amino Acid Sequence Animals Antimicrobial Cationic Peptides / chemical synthesis Anura / metabolism Circular Dichroism Escherichia coli / drug effects Hydrogen-Ion Concentration Liposomes / chemistry Molecular Dynamics Simulation Nuclear Magnetic Resonance, Biomolecular Protein Binding Protein Conformation, alpha-Helical Staphylococcus aureus / drug effects
Aggregation process Antimicrobial mechanism of action Biophysical prediction of peptidemembrane interactions Conformational analysis of peptides Membrane active peptides Peptide-membrane interaction

Journal

Biochimica et biophysica acta. Biomembranes
ISSN: 1879-2642
Titre abrégé: Biochim Biophys Acta Biomembr
Pays: Netherlands
ID NLM: 101731713

Informations de publication

Date de publication:
01 05 2021
Historique:
received: 11 11 2020
revised: 20 01 2021
accepted: 03 02 2021
pubmed: 9 2 2021
medline: 9 9 2021
entrez: 8 2 2021
Statut: ppublish

Résumé

Hylaseptin-4 (HSP-4, GIGDILKNLAKAAGKAALHAVGESL-NH

Identifiants

DOI: 10.1016/j.bbamem.2021.183581 PMID: 33556358
pubmed: 33556358
pii: S0005-2736(21)00032-8
doi: 10.1016/j.bbamem.2021.183581
pii:
doi:

Substances chimiques

Antimicrobial Cationic Peptides 0
Liposomes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

183581

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

L O Nunes (LO)

Departamento de Química, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, MG, Brazil.

V H O Munhoz (VHO)

Instituto de Ciência e Tecnologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, MG, Brazil.

A A Sousa (AA)

Departamento de Química, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, MG, Brazil.

K R de Souza (KR)

Departamento de Química, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, MG, Brazil.

T L Santos (TL)

Departamento de Química, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, MG, Brazil.

M P Bemquerer (MP)

Embrapa Recursos Genéticos e Biotecnologia, Parque Estação Biológica, PqEB, Av. W5 Norte (final), P.O. Box 02372, Brasília, DF, Brazil.

D E C Ferreira (DEC)

Departamento de Química, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, MG, Brazil; Departamento de Química, Universidade Federal de Minas Gerais, P.O. Box 486, 31270-901 Belo Horizonte, MG, Brazil.

Mariana T Q de Magalhães (MTQ)

Departamento de Bioquímica e Imunologia, Laboratório de Biofísica de Macromoléculas Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.

J M Resende (JM)

Departamento de Química, Universidade Federal de Minas Gerais, P.O. Box 486, 31270-901 Belo Horizonte, MG, Brazil.

A F C Alcântara (AFC)

Departamento de Química, Universidade Federal de Minas Gerais, P.O. Box 486, 31270-901 Belo Horizonte, MG, Brazil.

C Aisenbrey (C)

Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 67000 Strasbourg, France.

D P Veloso (DP)

Departamento de Química, Universidade Federal de Minas Gerais, P.O. Box 486, 31270-901 Belo Horizonte, MG, Brazil.

B Bechinger (B)

Université de Strasbourg/CNRS, UMR7177, Institut de Chimie, 67000 Strasbourg, France; Institut Universitaire de France (IUF), France.

R M Verly (RM)

Departamento de Química, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, MG, Brazil. Electronic address: verly.rodrigo@ufvjm.edu.br.

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › High-resolution structural profile of...
questionsmedicales.fr › Eucaryotes › Animaux › High-resolution structural profile of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Perforines › Peptides antimicrobiens cationiques › High-resolution structural profile of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Amphibiens › Anura › High-resolution structural profile of...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Dichroïsme circulaire › High-resolution structural profile of...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Escherichia › Escherichia coli › High-resolution structural profile of...
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › High-resolution structural profile of...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Liposomes › High-resolution structural profile of...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › High-resolution structural profile of...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Résonance magnétique nucléaire biomoléculaire › High-resolution structural profile of...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › High-resolution structural profile of...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure secondaire des protéines › Structure en hélice alpha › High-resolution structural profile of...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › High-resolution structural profile of...