Dramatic changes in mitochondrial substrate use at critically high temperatures: a comparative study using

Complex I Glycerol-3-phosphate dehydrogenase Mitochondrial flexibility Substrate control Thermal sensitivity Thermal tolerance

Journal

The Journal of experimental biology
ISSN: 1477-9145
Titre abrégé: J Exp Biol
Pays: England
ID NLM: 0243705

Informations de publication

Date de publication:
19 03 2021
Historique:
received: 23 11 2020
accepted: 21 01 2021
pubmed: 11 2 2021
medline: 10 7 2021
entrez: 10 2 2021
Statut: epublish

Résumé

Ectotherm thermal tolerance is critical to species distribution, but at present the physiological underpinnings of heat tolerance remain poorly understood. Mitochondrial function is perturbed at critically high temperatures in some ectotherms, including insects, suggesting that heat tolerance of these animals is linked to failure of oxidative phosphorylation (OXPHOS) and/or ATP production. To test this hypothesis, we measured mitochondrial oxygen consumption rate in six

Identifiants

pubmed: 33563650
pii: jeb.240960
doi: 10.1242/jeb.240960
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2021. Published by The Company of Biologists Ltd.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing or financial interests.

Auteurs

Lisa Bjerregaard Jørgensen (LB)

Zoophysiology, Department of Biology, Aarhus University, 8000 Aarhus C, Denmark lbj@bio.au.dk.

Johannes Overgaard (J)

Zoophysiology, Department of Biology, Aarhus University, 8000 Aarhus C, Denmark.

Florence Hunter-Manseau (F)

Department of Chemistry and Biochemistry, Université de Moncton, Moncton, NB, Canada, E1A 3E9.

Nicolas Pichaud (N)

Department of Chemistry and Biochemistry, Université de Moncton, Moncton, NB, Canada, E1A 3E9.

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Classifications MeSH