Hippocampal inflammation and oxidative stress following exposure to diesel exhaust nanoparticles in male and female mice.
Air Pollutants
/ adverse effects
Animals
Female
Hippocampus
/ drug effects
Inflammation Mediators
/ metabolism
Inhalation Exposure
/ adverse effects
Male
Mice
Nanoparticles
/ administration & dosage
Oxidative Stress
/ drug effects
Particulate Matter
/ administration & dosage
Sex Characteristics
Vehicle Emissions
Air pollution exposure
Diesel exhaust nano-particles
Hippocampal NMDA receptor
Neuro-inflammation
Oxidative stress
Journal
Neurochemistry international
ISSN: 1872-9754
Titre abrégé: Neurochem Int
Pays: England
ID NLM: 8006959
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
26
11
2020
revised:
17
01
2021
accepted:
10
02
2021
pubmed:
15
2
2021
medline:
19
11
2021
entrez:
14
2
2021
Statut:
ppublish
Résumé
Air pollution exposure is among the most prevalent reasons for environmentally-induced oxidative stress and inflammation, both of which are involved in the development and progression of central nervous system (CNS) diseases. Ultrafine particles (UFPs) plays an important role in global air pollution and the diesel exhaust particles (DEPs) are the most important component in this regard. There are more than 40 toxic air pollutants in diesel exhaust (DE), which is one of the main constituents of an environmental pollutant and including particulate matter (PM) especially UFPs. Thus, in this study, adult female and male NMRI mice were exposed to DEPs (350-400 μg/m
Identifiants
pubmed: 33582162
pii: S0197-0186(21)00035-8
doi: 10.1016/j.neuint.2021.104989
pii:
doi:
Substances chimiques
Air Pollutants
0
Inflammation Mediators
0
Particulate Matter
0
Vehicle Emissions
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
104989Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.