Comparison of the injection-site experience of the starting doses with semaglutide and dulaglutide: A randomized, double-blind trial in healthy subjects.


Journal

Diabetes, obesity & metabolism
ISSN: 1463-1326
Titre abrégé: Diabetes Obes Metab
Pays: England
ID NLM: 100883645

Informations de publication

Date de publication:
06 2021
Historique:
revised: 27 01 2021
received: 06 11 2020
accepted: 09 02 2021
pubmed: 17 2 2021
medline: 10 7 2021
entrez: 16 2 2021
Statut: ppublish

Résumé

This double-blind, randomized, single-site, crossover trial compared the injection-site experience with the starting doses of semaglutide and dulaglutide. Healthy subjects (aged 18-75 years; body mass index ≥ 25 kg/m

Identifiants

pubmed: 33591618
doi: 10.1111/dom.14349
pmc: PMC8251561
doi:

Substances chimiques

Hypoglycemic Agents 0
Immunoglobulin Fc Fragments 0
Recombinant Fusion Proteins 0
semaglutide 53AXN4NNHX
Glucagon-Like Peptides 62340-29-8
dulaglutide WTT295HSY5

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1415-1419

Subventions

Organisme : This trial was funded by Novo Nordisk A/S

Informations de copyright

© 2021 The Authors. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.

Références

Diabetes Metab Syndr Obes. 2017 Sep 29;10:403-412
pubmed: 29033597
Diabetes Metab Syndr Obes. 2020 Feb 18;13:433-438
pubmed: 32110076
Diabetes Obes Metab. 2021 Jun;23(6):1415-1419
pubmed: 33591618
J Diabetes Sci Technol. 2015 Apr 21;9(5):1071-9
pubmed: 25901022
Diabetes Ther. 2020 Jun;11(6):1199-1216
pubmed: 32297119
Diabetes Obes Metab. 2014 Oct;16(10):971-6
pubmed: 24720741
Diabetes Care. 2021 Jan;44(Suppl 1):S111-S124
pubmed: 33298420
Pharmacotherapy. 2002 Sep;22(9):1105-9
pubmed: 12222545
Clin Pharm. 1987 Sep;6(9):725-7
pubmed: 3677570
Ann Emerg Med. 1996 Apr;27(4):485-9
pubmed: 8604867
Somatosens Mot Res. 2006 Mar-Jun;23(1-2):37-43
pubmed: 16846958
Pain. 2009 Jul;144(1-2):35-42
pubmed: 19356853

Auteurs

Søren Snitker (S)

Novo Nordisk A/S, Søborg, Denmark.

Andreas Andersen (A)

Novo Nordisk A/S, Søborg, Denmark.

Birgitte Berg (B)

Novo Nordisk A/S, Søborg, Denmark.

Sjoerd van Marle (S)

PRA Health Sciences, Groningen, the Netherlands.

Thomas Sparre (T)

Novo Nordisk A/S, Søborg, Denmark.

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Classifications MeSH