Magnetic bioactive glasses/Cisplatin loaded-chitosan (CS)-grafted- poly (ε-caprolactone) nanofibers against bone cancer treatment.

Alkaline Phosphatase / chemistry Antineoplastic Agents / administration & dosage Apoptosis Bone Neoplasms / drug therapy Caproates Cell Line, Tumor Cell Survival Chitosan / chemistry Cisplatin / chemistry Drug Carriers / chemistry Drug Delivery Systems Drug Liberation Drug Screening Assays, Antitumor Glass Humans Lactones Magnetic Resonance Spectroscopy Microscopy, Electron, Scanning Nanofibers / chemistry Nanoparticles / chemistry Necrosis Polyesters / chemistry Tissue Engineering Tissue Scaffolds / chemistry X-Ray Diffraction
Bone cancer Cisplatin Drug release Magnetic bioactive glasses Nanofiber

Journal

Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156

Informations de publication

Date de publication:
15 Apr 2021
Historique:
received: 27 07 2020
revised: 31 10 2020
accepted: 17 01 2021
entrez: 17 2 2021
pubmed: 18 2 2021
medline: 22 5 2021
Statut: ppublish

Résumé

The bioactive glasses (BGs)/Cisplatin and magnetic bioactive glasses (MBGs)/Cisplatin were doped into the chitosan (CS)-grafted- poly (ε-caprolactone) (PCL) nanofibers for controlled release of Cisplatin under various pH values and temperatures. The simultaneous effect of chemotherapy and hyperthermia was investigated against MG-63 osteosarcoma cells by treating of cells with Cs-g-PCL/MBGs/Cisplatin under an alternating magnetic field. The synthesized nanofibers were characterized using XRD, FTIR,

Identifiants

DOI: 10.1016/j.carbpol.2021.117680 PMID: 33593554
pubmed: 33593554
pii: S0144-8617(21)00067-9
doi: 10.1016/j.carbpol.2021.117680
pii:
doi:

Substances chimiques

Antineoplastic Agents 0
Caproates 0
Drug Carriers 0
Lactones 0
Polyesters 0
polycaprolactone 24980-41-4
caprolactone 56RE988L1R
Chitosan 9012-76-4
Alkaline Phosphatase EC 3.1.3.1
Cisplatin Q20Q21Q62J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

117680

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Zahra Amini (Z)

Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Sam Shekofte Rudsary (SS)

Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.

Seyed Sadegh Shahraeini (SS)

Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.

Babak Faraji Dizaji (BF)

Faculty of Pharmacy and Pharmaceutical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Pouya Goleij (P)

Department of Genetics, Faculty of Biology, Sana Institute of Higher Education, Sari, Iran.

Ameneh Bakhtiari (A)

Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran.

Mohammad Irani (M)

Faculty of Pharmacy, Alborz University of Medical Sciences, Karaj, Iran; Dentistry Clinical Research Development Unit, Alborz University of Medical Sciences, Karaj, Iran. Electronic address: m.irani@abzums.ac.ir.

Fariborz Sharifianjazi (F)

Department of Materials and Metallurgical Engineering, Amirkabir University of Technology, Tehran, Iran.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Phosphoric monoester hydrolases › Phosphatase alcaline › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Maladies ostéomusculaires › Maladies osseuses › Tumeurs osseuses › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Lipides › Acides gras › Acides gras volatils › Caproates › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Glucides › Polyosides › Chitine › Chitosane › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du platine › Cisplatine › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Vecteurs de médicaments › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Libération de médicament › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de criblage d'agents antitumoraux › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Verre › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Composés chimiques organiques › Lactones › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Microscopie électronique à balayage › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanofibres › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Nécrose › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Polyesters › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Ingénierie tissulaire › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Équipement et fournitures › Prothèses et implants › Structures d'échafaudage tissulaires › Magnetic bioactive glasses/Cisplatin...
questionsmedicales.fr › Phénomènes chimiques › Diffraction des rayons X › Magnetic bioactive glasses/Cisplatin...