The Sialoglycan Binding Adhesins of Mycoplasma genitalium and Mycoplasma pneumoniae.

Adhesins, Bacterial / chemistry Cryoelectron Microscopy Crystallography, X-Ray Glycoproteins / metabolism Humans Immune Evasion Mycoplasma genitalium / chemistry Mycoplasma pneumoniae / chemistry N-Acetylneuraminic Acid / chemistry
antigenic variation bacterial cytoadhesins protein structure receptor binding

Journal

Trends in microbiology
ISSN: 1878-4380
Titre abrégé: Trends Microbiol
Pays: England
ID NLM: 9310916

Informations de publication

Date de publication:
06 2021
Historique:
received: 01 12 2020
revised: 23 01 2021
accepted: 25 01 2021
pubmed: 18 2 2021
medline: 19 11 2021
entrez: 17 2 2021
Statut: ppublish

Résumé

Mycoplasma genitalium (Mge) and Mycoplasma pneumoniae (Mpn) are two human pathogens associated with urogenital and respiratory tract infections, respectively. The recent elucidation of the tridimensional structure of their major cytoadhesins by X-ray crystallography and cryo-electron microscopy/tomography, has provided important insights regarding the mechanics of infection and evasion of immune surveillance.

Identifiants

DOI: 10.1016/j.tim.2021.01.011 PMID: 33593698
pubmed: 33593698
pii: S0966-842X(21)00013-5
doi: 10.1016/j.tim.2021.01.011
pii:
doi:

Substances chimiques

Adhesins, Bacterial 0
Glycoproteins 0
N-Acetylneuraminic Acid GZP2782OP0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

477-481

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests No interests are declared.

Auteurs

David Vizarraga (D)

Instituto de Biología Molecular de Barcelona (IBMB-CSIC), Parc Científic de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain.

Sergi Torres-Puig (S)

Research Unit of Molecular Microbiology (RUMM), Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.

David Aparicio (D)

Instituto de Biología Molecular de Barcelona (IBMB-CSIC), Parc Científic de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain. Electronic address: daacri@ibmb.csic.es.

Oscar Q Pich (OQ)

Laboratori de Recerca en Microbiologia i Malalties Infeccioses, Institut d'Investigació i Innovació Parc Taulí (I3PT), Hospital Universitari Parc Taulí, Universitat Autònoma de Barcelona, 08208 Sabadell, Spain; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain. Electronic address: oquijada@tauli.cat.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes bactériens › Adhésines bactériennes › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Cryomicroscopie électronique › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Glycoprotéines › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Phénomènes biologiques › Interactions hôte-microbes › Interactions hôte-pathogène › Échappement immunitaire › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Tenericutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma genitalium › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Tenericutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma pneumoniae › The Sialoglycan Binding Adhesins of Mycoplasma...
questionsmedicales.fr › Glucides › Oses acides › Acides neuraminiques › Acides sialiques › Acide N-acétyl-neuraminique › The Sialoglycan Binding Adhesins of Mycoplasma...