GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.
Animals
Apoptosis
Biomarkers, Tumor
/ genetics
Bone Marrow Neoplasms
/ genetics
Cell Proliferation
Chromosome Deletion
Gene Expression Regulation, Neoplastic
Humans
Mice
Mice, SCID
N-Myc Proto-Oncogene Protein
/ genetics
Nerve Tissue Proteins
/ deficiency
Neuroblastoma
/ genetics
Prognosis
Survival Rate
Tumor Cells, Cultured
Xenograft Model Antitumor Assays
Zebrafish
Journal
Cancer research
ISSN: 1538-7445
Titre abrégé: Cancer Res
Pays: United States
ID NLM: 2984705R
Informations de publication
Date de publication:
01 06 2021
01 06 2021
Historique:
received:
03
06
2020
revised:
04
01
2021
accepted:
15
02
2021
pubmed:
20
2
2021
medline:
5
11
2021
entrez:
19
2
2021
Statut:
ppublish
Résumé
One of the greatest barriers to curative treatment of neuroblastoma is its frequent metastatic outgrowth prior to diagnosis, especially in cases driven by amplification of the
Identifiants
pubmed: 33602789
pii: 0008-5472.CAN-20-1890
doi: 10.1158/0008-5472.CAN-20-1890
pmc: PMC8178188
mid: NIHMS1677041
doi:
Substances chimiques
Biomarkers, Tumor
0
GAS7 protein, human
0
MYCN protein, human
0
N-Myc Proto-Oncogene Protein
0
Nerve Tissue Proteins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2995-3007Subventions
Organisme : NCI NIH HHS
ID : K08 CA215105
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA124709
Pays : United States
Organisme : NCI NIH HHS
ID : R35 CA220500
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA180692
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA240323
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA015083
Pays : United States
Organisme : NCI NIH HHS
ID : R35 CA210064
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
©2021 American Association for Cancer Research.
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