Age-dependent remodeling of gut microbiome and host serum metabolome in mice.
aging
gut microbiome
metabolism
serum metabolome
Journal
Aging
ISSN: 1945-4589
Titre abrégé: Aging (Albany NY)
Pays: United States
ID NLM: 101508617
Informations de publication
Date de publication:
17 02 2021
17 02 2021
Historique:
received:
10
09
2020
accepted:
04
01
2021
pubmed:
23
2
2021
medline:
27
7
2021
entrez:
22
2
2021
Statut:
ppublish
Résumé
The interplay between microbiota and host metabolism plays an important role in health. Here, we examined the relationship between age, gut microbiome and host serum metabolites in male C57BL/6J mice. Fecal microbiome analysis of 3, 6, 18, and 28 months (M) old mice showed that the
Identifiants
pubmed: 33612480
pii: 202525
doi: 10.18632/aging.202525
pmc: PMC7993679
doi:
Substances chimiques
Indoles
0
Kynurenine
343-65-7
indole-3-lactic acid
5SW11R7M7M
indole
8724FJW4M5
Tryptophan
8DUH1N11BX
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6330-6345Subventions
Organisme : NIA NIH HHS
ID : R01 AG064869
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK118334
Pays : United States
Organisme : NIA NIH HHS
ID : R21 AG061726
Pays : United States
Organisme : NIA NIH HHS
ID : R56 AG063746
Pays : United States
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