Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection?

SARS-CoV-2 VA ECMO cardiogenic shock coronavirus disease-19 fulminant myocarditis

Journal

Future cardiology
ISSN: 1744-8298
Titre abrégé: Future Cardiol
Pays: England
ID NLM: 101239345

Informations de publication

Date de publication:
11 2021
Historique:
pubmed: 23 2 2021
medline: 1 12 2021
entrez: 22 2 2021
Statut: ppublish

Résumé

We describe a unique case of fulminant myocarditis in a patient with presumed SARS-CoV-2 reinfection. Patient had initial infection 4 months backand had COVID-19 antibody at the time of presentation. Endomyocardial biopsy showed lymphocytic myocarditis, that is usually seen in viral myocarditis. The molecular diagnostic testing of the endomyocardial biopsy for cardiotropic viruses was positive for Parvovirus and negative for SARS-CoV-2. Authors highly suspect co-infection of SARS-CoV-2 and Parvovirus, that possibly triggered the immune cascade resulting in fulminant myocarditis. Patient was hemodynamically unstable with ventricular tachycardia and was supported on VA ECMO and Impella CP. There was impressive recovery of left ventricular function within 48 h, leading to decannulation of VA ECMO in 72 h. This unique case was written by the survivor herself.

Identifiants

pubmed: 33615872
doi: 10.2217/fca-2020-0237
pmc: PMC7919708
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1307-1311

Auteurs

Ramya Yeleti (R)

College of Osteopathic Medicine, Marion University, 3200 Cold Spring Rd, Indianapolis, IN 46222, USA.
Patient Author, Carmel, Indiana, IN 46032, USA.

Maya Guglin (M)

Division of Cardiology, Krannert Institute of Cardiology at Indiana University School of Medicine, 1800 N Capital Ave, Indianapolis, IN 46202, USA.

Kashif Saleem (K)

Division of Cardiothoracic Surgery, Indiana University School of Medicine, 1701 N Senate Blvd, Indianapolis, IN 46202, USA.

Sasikanth V Adigopula (SV)

Division of Cardiology, Community Heart & Vascular Hospital, 8075 Shadeland Ave, Indianapolis, IN 46250, USA.

Anjan Sinha (A)

Division of Cardiology, Krannert Institute of Cardiology at Indiana University School of Medicine, 1800 N Capital Ave, Indianapolis, IN 46202, USA.

Smrity Upadhyay (S)

Division of Infectious Disease, Indiana University School of Medicine, 545 Barnhill Dr. Emerson Hall 305, Indianapolis, IN 46202, USA.

Jeffrey E Everett (JE)

Division of Cardiothoracic Surgery, Indiana University School of Medicine, 1701 N Senate Blvd, Indianapolis, IN 46202, USA.

Kareem Ballut (K)

Division of Cardiology, Krannert Institute of Cardiology at Indiana University School of Medicine, 1800 N Capital Ave, Indianapolis, IN 46202, USA.

Sarada Uppuluri (S)

Division of Cardiology, Community Heart & Vascular Hospital, 8075 Shadeland Ave, Indianapolis, IN 46250, USA.

Roopa A Rao (RA)

Division of Cardiology, Krannert Institute of Cardiology at Indiana University School of Medicine, 1800 N Capital Ave, Indianapolis, IN 46202, USA.

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Classifications MeSH