Inhibitory Effects of Secondary Metabolites from the Lichen Stereocaulon evolutum on Protein Tyrosine Phosphatase 1B.

Ascomycota / chemistry Diabetes Mellitus, Type 2 Enzyme Inhibitors / pharmacology Lichens / chemistry Protein Tyrosine Phosphatase, Non-Receptor Type 1 / antagonists & inhibitors

Journal

Planta medica
ISSN: 1439-0221
Titre abrégé: Planta Med
Pays: Germany
ID NLM: 0066751

Informations de publication

Date de publication:
Aug 2021
Historique:
pubmed: 23 2 2021
medline: 6 8 2021
entrez: 22 2 2021
Statut: ppublish

Résumé

Protein tyrosine phosphatase 1B plays a significant role in type 2 diabetes mellitus and other diseases and is therefore considered a new drug target. Within this study, an acetone extract from the lichen

Identifiants

DOI: 10.1055/a-1334-4480 PMID: 33618379
pubmed: 33618379
doi: 10.1055/a-1334-4480
doi:

Substances chimiques

Enzyme Inhibitors 0
Protein Tyrosine Phosphatase, Non-Receptor Type 1 EC 3.1.3.48

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

701-708

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare that they have no conflict of interest.

Auteurs

Thi Huyen Vu (TH)

University of Rennes, CNRS, ISCR - UMR 6226, Rennes, France.

Olivier Delalande (O)

University of Rennes, CNRS, IGDR - UMR 6290, Rennes, France.

Claudia Lalli (C)

University of Rennes, CNRS, ISCR - UMR 6226, Rennes, France.

Stefanie Reider (S)

Institute of Pharmacy/Pharmacognosy, University of Innsbruck and Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria.

Solenn Ferron (S)

University of Rennes, CNRS, ISCR - UMR 6226, Rennes, France.

Joel Boustie (J)

University of Rennes, CNRS, ISCR - UMR 6226, Rennes, France.

Birgit Waltenberger (B)

Institute of Pharmacy/Pharmacognosy, University of Innsbruck and Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria.
ORCID: 0000-0002-2718-4677

Françoise Lohézic-Le Dévéhat (F)

University of Rennes, CNRS, ISCR - UMR 6226, Rennes, France.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Ascomycota › Inhibitory Effects of Secondary Metabolites...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabète de type 2 › Inhibitory Effects of Secondary Metabolites...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibitory Effects of Secondary Metabolites...
questionsmedicales.fr › Stades d'organismes › Lichens › Inhibitory Effects of Secondary Metabolites...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein Tyrosine Phosphatases › Protein Tyrosine Phosphatases, Non-Receptor › Protein Tyrosine Phosphatase, Non-Receptor Type 1 › Inhibitory Effects of Secondary Metabolites...