Sugammadex Administration in Pregnant Women: A Case Series of Maternal and Fetal Outcomes.
Journal
A&A practice
ISSN: 2575-3126
Titre abrégé: A A Pract
Pays: United States
ID NLM: 101714112
Informations de publication
Date de publication:
24 Feb 2021
24 Feb 2021
Historique:
entrez:
24
2
2021
pubmed:
25
2
2021
medline:
29
7
2021
Statut:
epublish
Résumé
Sugammadex, given its high affinity for amino-steroid neuromuscular blockers, offers rapid and reliable neuromuscular blockade reversal, making it a popular reversal agent. This characteristic can be very useful in pregnant women, where incomplete reversal can have poor maternal and fetal outcomes. However, its use antenatally in pregnancy is controversial given concerns for progesterone binding, a hormone that is crucial for maintenance of pregnancy. This case series presents obstetric and fetal outcomes in 25 pregnant women who received sugammadex during the antenatal period, thus highlighting the need for further research into the safety of sugammadex during pregnancy.
Identifiants
pubmed: 33626026
doi: 10.1213/XAA.0000000000001407
pii: 02054229-202102000-00024
doi:
Substances chimiques
Neuromuscular Nondepolarizing Agents
0
gamma-Cyclodextrins
0
Sugammadex
361LPM2T56
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e01407Informations de copyright
Copyright © 2021 International Anesthesia Research Society.
Déclaration de conflit d'intérêts
Conflicts of Interest: None.
Références
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