Association of haemoglobin levels in the first trimester and at 26-30 weeks with fetal and neonatal outcomes: a secondary analysis of the Global Network for Women's and Children's Health's ASPIRIN Trial.
Haemoglobin levels
low- and middle-income countries
pregnancy outcomes
Journal
BJOG : an international journal of obstetrics and gynaecology
ISSN: 1471-0528
Titre abrégé: BJOG
Pays: England
ID NLM: 100935741
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
accepted:
27
01
2021
pubmed:
26
2
2021
medline:
3
8
2021
entrez:
25
2
2021
Statut:
ppublish
Résumé
Limited data are available from low- and middle-income countries (LMICs) on the relationship of haemoglobin levels to adverse outcomes at different times during pregnancy. We evaluated the association of haemoglobin levels in nulliparous women at two times in pregnancy with pregnancy outcomes. ASPIRIN Trial data were used to study the association between haemoglobin levels measured at 6 Obstetric care facilities in Pakistan, India, Kenya, Zambia, The Democratic Republic of the Congo and Guatemala. A total of 11 976 pregnant women. Generalised linear models were used to obtain adjusted relative risks and 95% CI for adverse outcomes. Preterm birth, stillbirth, neonatal death, small for gestational age (SGA) and birthweight <2500 g. The mean haemoglobin levels at 6 Both lower and some higher haemoglobin concentrations are associated with adverse fetal and neonatal outcomes at 6 Both lower and some higher haemoglobin concentrations were associated with adverse fetal and neonatal outcomes at 6-13 weeks and 26-30 weeks of gestation.
Identifiants
pubmed: 33629490
doi: 10.1111/1471-0528.16676
pmc: PMC8286300
mid: NIHMS1689759
doi:
Substances chimiques
Hemoglobins
0
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1487-1496Subventions
Organisme : NICHD NIH HHS
ID : U24 HD092094
Pays : United States
Organisme : NICHD NIH HHS
ID : UG1 HD078439
Pays : United States
Organisme : NICHD NIH HHS
ID : U10 HD076465
Pays : United States
Organisme : NICHD NIH HHS
ID : UG1 HD076465
Pays : United States
Organisme : NICHD NIH HHS
ID : UG1 HD076457
Pays : United States
Organisme : NICHD NIH HHS
ID : UG1 HD076474
Pays : United States
Informations de copyright
© 2021 John Wiley & Sons Ltd.
Références
Trop Med Int Health. 2004 Apr;9(4):486-90
pubmed: 15078267
Int J Reprod Biomed. 2017 Mar;15(3):125-134
pubmed: 28580444
Am J Clin Nutr. 2000 Jul;72(1 Suppl):272S-279S
pubmed: 10871593
Food Nutr Bull. 2015 Jun;36(2 Suppl):S119-28
pubmed: 26125197
Hypertension. 2014 Jul;64(1):36-44
pubmed: 24821945
Am J Obstet Gynecol. 2005 Jul;193(1):220-6
pubmed: 16021083
Acta Obstet Gynecol Scand. 1993 May;72(4):246-51
pubmed: 8389509
Obstet Gynecol. 2000 Nov;96(5 Pt 1):741-8
pubmed: 11042311
J Clin Epidemiol. 1990;43(5):461-6
pubmed: 2324786
Ann N Y Acad Sci. 2019 Aug;1450(1):69-82
pubmed: 31148191
Int J Gynaecol Obstet. 2012 Sep;118(3):190-3
pubmed: 22738806
Trop Med Int Health. 2008 Oct;13(10):1267-71
pubmed: 18721184
Am J Clin Nutr. 1992 May;55(5):985-8
pubmed: 1570808
Obstet Gynecol. 2017 May;129(5):e150-e154
pubmed: 28426621
Am J Clin Nutr. 2017 Dec;106(Suppl 6):1694S-1702S
pubmed: 29070565
Lancet. 2020 Jan 25;395(10220):285-293
pubmed: 31982074
Health Place. 2013 Nov;24:54-64
pubmed: 24042090
BJOG. 2019 May;126(6):737-743
pubmed: 30554474
Am J Epidemiol. 2011 Oct 1;174(7):797-806
pubmed: 21859836
BMC Pregnancy Childbirth. 2017 May 3;17(1):135
pubmed: 28468653
Ann N Y Acad Sci. 2019 Aug;1450(1):47-68
pubmed: 30994929
J Matern Fetal Neonatal Med. 2014 May;27(7):729-32
pubmed: 23981184
Semin Perinatol. 1981 Apr;5(2):155-62
pubmed: 7198826
Clin Nutr. 2003 Jun;22(3):271-5
pubmed: 12765667
Turk J Obstet Gynecol. 2018 Sep;15(3):165-170
pubmed: 30202626
BMJ Glob Health. 2016 Apr 7;1(1):e000026
pubmed: 28588921
Obstet Gynecol. 2019 Dec;134(6):1234-1244
pubmed: 31764734
Reprod Health. 2015;12 Suppl 2:S1
pubmed: 26063166