Evaluating the Effectiveness of a Web-Based Program (POP4Teens) to Prevent Prescription Opioid Misuse Among Adolescents: Randomized Controlled Trial.
adolescent
internet
opioids
prevention and control
randomized controlled trial
Journal
JMIR public health and surveillance
ISSN: 2369-2960
Titre abrégé: JMIR Public Health Surveill
Pays: Canada
ID NLM: 101669345
Informations de publication
Date de publication:
25 02 2021
25 02 2021
Historique:
received:
28
02
2020
accepted:
13
01
2021
revised:
21
12
2020
entrez:
25
2
2021
pubmed:
26
2
2021
medline:
11
9
2021
Statut:
epublish
Résumé
Prescription opioid (PO) use is common among adolescents in the United States. Despite recent declines from unprecedented peaks in adolescent PO use (eg, in 2012-2013), there is seemingly paradoxical evidence that PO-related consequences (eg, opioid use disorder and overdoses) are increasing. These trends and their possible consequences emphasize the importance of prevention efforts targeting PO misuse. To our knowledge, we have developed the first interactive web-based program (POP4Teens [P4T]) focused specifically on the prevention of PO misuse among adolescents. This study aimed to evaluate the effectiveness of P4T, a web-based program designed to prevent adolescent PO misuse, in comparison with JustThinkTwice (JTT), an active control website, on PO-related attitudes, knowledge, risk perception, and intentions to use. We conducted a web-based randomized controlled trial in 2018. A total of 406 adolescents (aged 12-17 years) were randomly assigned to either P4T or JTT. The outcome variables were attitudes, knowledge, and risk perceptions associated with PO misuse, intentions to use POs, and program feedback. Data were collected at baseline and at 1, 3, and 6 months. Both programs resulted in significant and sustained improvements in intention to use POs, increased perceived risk, impacted expectancies consistent with prevention, and improved PO refusal skills. P4T produced significantly greater increases in PO-related knowledge than JTT did, and it was reportedly easier to use and more liked. Baseline scores for youth reporting past-year medical use of POs, friends who engage in nonmedical use of POs, and/or poor mental health underscored their at-risk status compared with youth from the other groups. P4T positively impacted all study variables that are known to prevent PO misuse among teens. Moreover, its web-based nature simplifies the dissemination and implementation of this novel tool designed to help meet the challenges of the evolving national opioid crisis. ClinicalTrials.gov NCT02737696; https://clinicaltrials.gov/ct2/show/NCT02737696.
Sections du résumé
BACKGROUND
Prescription opioid (PO) use is common among adolescents in the United States. Despite recent declines from unprecedented peaks in adolescent PO use (eg, in 2012-2013), there is seemingly paradoxical evidence that PO-related consequences (eg, opioid use disorder and overdoses) are increasing. These trends and their possible consequences emphasize the importance of prevention efforts targeting PO misuse. To our knowledge, we have developed the first interactive web-based program (POP4Teens [P4T]) focused specifically on the prevention of PO misuse among adolescents.
OBJECTIVE
This study aimed to evaluate the effectiveness of P4T, a web-based program designed to prevent adolescent PO misuse, in comparison with JustThinkTwice (JTT), an active control website, on PO-related attitudes, knowledge, risk perception, and intentions to use.
METHODS
We conducted a web-based randomized controlled trial in 2018. A total of 406 adolescents (aged 12-17 years) were randomly assigned to either P4T or JTT. The outcome variables were attitudes, knowledge, and risk perceptions associated with PO misuse, intentions to use POs, and program feedback. Data were collected at baseline and at 1, 3, and 6 months.
RESULTS
Both programs resulted in significant and sustained improvements in intention to use POs, increased perceived risk, impacted expectancies consistent with prevention, and improved PO refusal skills. P4T produced significantly greater increases in PO-related knowledge than JTT did, and it was reportedly easier to use and more liked. Baseline scores for youth reporting past-year medical use of POs, friends who engage in nonmedical use of POs, and/or poor mental health underscored their at-risk status compared with youth from the other groups.
CONCLUSIONS
P4T positively impacted all study variables that are known to prevent PO misuse among teens. Moreover, its web-based nature simplifies the dissemination and implementation of this novel tool designed to help meet the challenges of the evolving national opioid crisis.
TRIAL REGISTRATION
ClinicalTrials.gov NCT02737696; https://clinicaltrials.gov/ct2/show/NCT02737696.
Identifiants
pubmed: 33629961
pii: v7i2e18487
doi: 10.2196/18487
pmc: PMC8128362
doi:
Banques de données
ClinicalTrials.gov
['NCT02737696']
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
e18487Subventions
Organisme : NIDA NIH HHS
ID : P30 DA029926
Pays : United States
Informations de copyright
©Lisa A Marsch, Sarah K Moore, Michael Grabinski, Sarah Y Bessen, Jacob Borodovsky, Emily Scherer. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 25.02.2021.
Références
Prev Sci. 2015 Jul;16(5):633-41
pubmed: 25344348
Int J Drug Policy. 2012 Sep;23(5):374-84
pubmed: 22417823
Drug Alcohol Depend. 2008 Apr 1;94(1-3):1-11
pubmed: 18054444
Prev Sci. 2008 Sep;9(3):191-201
pubmed: 18633709
Addiction. 2001 Jan;96(1):57-72
pubmed: 11177520
Behav Anal. 1996 Fall;19(2):289-92
pubmed: 22478265
PLoS Med. 2019 Nov 5;16(11):e1002922
pubmed: 31689290
J Adolesc Health. 2007 Jan;40(1):76-83
pubmed: 17185209
Child Adolesc Psychiatr Clin N Am. 2016 Oct;25(4):755-68
pubmed: 27613350
Clin Psychol Sci. 2018 Sep;6(5):629-646
pubmed: 30333942
Adolesc Med State Art Rev. 2011 Dec;22(3):649-69, xiv
pubmed: 22423469
J Adolesc Health. 2018 Nov;63(5):594-600
pubmed: 30348282
Addict Behav. 2017 Feb;65:229-235
pubmed: 27561431
Int J Drug Policy. 2014 Mar;25(2):257-66
pubmed: 24238956
J Adv Nurs. 2007 Dec;60(5):544-9
pubmed: 17973718
Patient Educ Couns. 2007 Jun;66(3):303-10
pubmed: 17298873
JAMA Netw Open. 2018 Dec 7;1(8):e186558
pubmed: 30646334
Rev Saude Publica. 2019 Oct 21;53:96
pubmed: 31644774
Addict Behav Rep. 2015 Dec 1;2:33-36
pubmed: 26086039
J Am Acad Child Adolesc Psychiatry. 2009 Aug;48(8):828-836
pubmed: 19564803
Psychol Addict Behav. 2008 Dec;22(4):563-9
pubmed: 19071982
Addict Behav. 2017 Nov;74:13-19
pubmed: 28558335
Subst Use Misuse. 2011;46(1):35-45
pubmed: 21190404
Addiction. 2016 Aug;111(8):1406-15
pubmed: 26918564
JMIR Form Res. 2019 Jul 19;3(3):e12389
pubmed: 31325289
Tenn Med. 2009 Apr;102(4):28-9
pubmed: 19385366
Soc Psychiatry Psychiatr Epidemiol. 2015 May;50(5):713-24
pubmed: 25427665
Addiction. 2007 Dec;102(12):1920-30
pubmed: 17916222
J Addict Dis. 2012;31(4):332-41
pubmed: 23244552
Addict Behav. 2018 Jul;82:101-104
pubmed: 29505985
Prev Sci. 2010 Mar;11(1):24-32
pubmed: 19728091
J Adolesc Health. 2018 Aug;63(2):245-248
pubmed: 30149925
NCHS Data Brief. 2017 Aug;(282):1-8
pubmed: 29155681
JAMA Pediatr. 2017 Aug 1;171(8):747-755
pubmed: 28628701
Addiction. 2009 Nov;104(11):1807-19
pubmed: 19744139
Addict Sci Clin Pract. 2015 Feb 24;10:5
pubmed: 25928221
J Stud Alcohol Drugs. 2015 Jan;76(1):5-20
pubmed: 25486389
Addict Behav. 2007 Mar;32(3):562-75
pubmed: 16843611
Am Psychol. 1992 Nov;47(11):1475-90
pubmed: 1482008
Pediatrics. 2017 Apr;139(4):
pubmed: 28320868
J Dual Diagn. 2013;9(1):101-103
pubmed: 23599690
J Rural Health. 2016 Spring;32(2):204-18
pubmed: 26344571
J Adolesc Health. 2016 Oct;59(4S):S61-S75
pubmed: 27664597
Pediatrics. 2015 Nov;136(5):e1169-77
pubmed: 26504126
J Med Internet Res. 2018 Aug 23;20(8):e255
pubmed: 30139724
Drug Alcohol Depend. 2006 Jan 4;81(1):37-45
pubmed: 16040201
Cochrane Database Syst Rev. 2014;(12):CD003020
pubmed: 25435250
J Subst Abuse Treat. 2015 Dec;59:30-7
pubmed: 26293644
Addict Behav. 2004 Nov;29(8):1503-15
pubmed: 15451120
JAMA Psychiatry. 2014 Jul 1;71(7):821-6
pubmed: 24871348
Arch Pediatr Adolesc Med. 2012 Sep 1;166(9):803-7
pubmed: 22566515
Psychol Addict Behav. 2019 Feb;33(1):26-34
pubmed: 30407027
Pediatrics. 2013 Nov;132(5):825-32
pubmed: 24167166
Int J Drug Policy. 2019 Sep;71:183-188
pubmed: 30718120
Drug Alcohol Rev. 2013 Mar;32(2):115-23
pubmed: 23039085
JAMA Psychiatry. 2019 Feb 1;76(2):208-216
pubmed: 30516809
MMWR Surveill Summ. 2018 Jun 15;67(8):1-114
pubmed: 29902162
J Addict Med. 2015 Sep-Oct;9(5):376-82
pubmed: 26291544
Nurse Res. 2005;13(2):55-70
pubmed: 16416980
JAMA. 2015 Oct 13;314(14):1468-78
pubmed: 26461997
Psychol Addict Behav. 2013 Sep;27(3):714-22
pubmed: 22686965
Arch Pediatr Adolesc Med. 2007 Mar;161(3):276-81
pubmed: 17339509
Pediatrics. 2019 Mar;143(3):
pubmed: 30804077
Soc Psychiatry Psychiatr Epidemiol. 2005 Jun;40(6):454-66
pubmed: 16003595
Appl Health Econ Health Policy. 2015 Apr;13(2):181-92
pubmed: 25617182
Adolesc Med State Art Rev. 2007 Aug;18(2):342-56, xii
pubmed: 18605650
Addiction. 2014 May;109(5):786-97
pubmed: 24372937
JAMA Psychiatry. 2019 Sep 1;76(9):941-947
pubmed: 31116357
J Med Internet Res. 2019 Jan 30;21(1):e11297
pubmed: 30698526
Behav Anal. 1996 Fall;19(2):163-97
pubmed: 22478257
Drug Alcohol Depend. 2016 Jan 1;158:132-8
pubmed: 26653341
J Adolesc Health. 2005 Jul;37(1):44-51
pubmed: 15963906
Addiction. 2010 Apr;105(4):749-59
pubmed: 20148791