Porous assembly of an antifungal protein mediated by zinc and sulfonato-calix[8]arene.
Assembly
Biohybrid
Framework
Macrocycle
Porosity
Journal
Journal of structural biology
ISSN: 1095-8657
Titre abrégé: J Struct Biol
Pays: United States
ID NLM: 9011206
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
15
12
2020
revised:
16
02
2021
accepted:
18
02
2021
pubmed:
26
2
2021
medline:
27
1
2022
entrez:
25
2
2021
Statut:
ppublish
Résumé
Controlled protein assembly holds great potential in the fabrication of biohybrid materials. However, the structural diversity and complexity of proteins present an obstacle to controlled assembly. Supramolecular chemistry is a possible solution as it offers tools to mediate self-assembly with molecular precision. This paper deals with the calixarene- and zinc-mediated assembly and crystallization of the histidine-rich Penicillium chrysogenum antifungal protein B (PAFB). We report crystal structures of pure PAFB, PAFB in complex with Zn
Identifiants
pubmed: 33631304
pii: S1047-8477(21)00016-2
doi: 10.1016/j.jsb.2021.107711
pii:
doi:
Substances chimiques
Antifungal Agents
0
Bacterial Proteins
0
Solutions
0
calix(8)arenesulfonate
0
Calixarenes
130036-26-9
Zinc
J41CSQ7QDS
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
107711Subventions
Organisme : Austrian Science Fund FWF
ID : I 3132
Pays : Austria
Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.