Large-scale food fortification has great potential to improve child health and nutrition.
Journal
Current opinion in clinical nutrition and metabolic care
ISSN: 1473-6519
Titre abrégé: Curr Opin Clin Nutr Metab Care
Pays: England
ID NLM: 9804399
Informations de publication
Date de publication:
01 05 2021
01 05 2021
Historique:
pubmed:
26
2
2021
medline:
13
4
2021
entrez:
25
2
2021
Statut:
ppublish
Résumé
Undernutrition, including micronutrient deficiencies, continues to plague children across the world, particularly in low and middle-income countries (LMICs). The situation has worsened alongside the SARS-CoV-2 pandemic because of major systemic disruptions to food supply, healthcare, and employment. Large-scale food fortification (LSFF) is a potential strategy for improving micronutrient intakes through the addition of vitamins and minerals to staple foods and improving the nutritional status of populations at large. Current evidence unquestionably supports the use of LSFF to improve micronutrient status. Evidence syntheses have also demonstrated impact on some functional outcomes, including anemia, wasting, underweight, and neural tube defects, that underpin poor health and development. Importantly, many of these effects have also been reflected in effectiveness studies that examine LSFF in real-world situations as opposed to under-controlled environments. However, programmatic challenges must be addressed in LMICs in order for LSFF efforts to reach their full potential. LSFF is an important strategy that has the potential to improve the health and nutrition of entire populations of vulnerable children. Now more than ever, existing programs should be strengthened and new programs implemented in areas with widespread undernutrition and micronutrient deficiencies.
Identifiants
pubmed: 33631771
doi: 10.1097/MCO.0000000000000745
pii: 00075197-202105000-00013
doi:
Substances chimiques
Micronutrients
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
271-275Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Références
2020 Global Nutrition Report: action on equity to end malnutrition. Bristol, UK Development Initiatives. Available from: https://globalnutritionreport.org/reports/2020-global-nutrition-report/ . [Accessed 6 January 2021]
Stevens GA, Bennett JE, Hennocq Q, et al. Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: a pooled analysis of population-based surveys. Lancet Glob Health 2015; 3:e528–e536.
Stevens GA, Finucane MM, De-Regil LM, et al. Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and nonpregnant women for 1995–2011: a systematic analysis of population-representative data. Lancet Glob Health 2013; 1:e16–e25.
Carducci B, Keats EC, Ruel M, et al. Food systems, diets and nutrition in the wake of COVID-19 [in press]. Nat Food 2020.
Garrett G, Matthias D, Keats EC, et al. Doubling down on food fortification to fortify the future. Seattle, WA: Bill & Melinda Gates Foundation; 2019.
Osendarp SJM, Martinez H, Garrett GS, et al. Large-scale food fortification and biofortification in low- and middle-income countries: a review of programs, trends, challenges, and evidence gaps. Food Nutr Bull 2018; 39:315–331.
Chadare FJ, Idohou R, Nago E, et al. Conventional and food-to-food fortification: an appraisal of past practices and lessons learned. Food Sci Nutr 2019; 7:2781–2795.
Tam E, Keats EC, Rind F, et al. Micronutrient supplementation and fortification interventions on health and development outcomes among children under-five in low- and middle-income countries: a systematic review and meta-analysis. Nutrients 2020; 12:289.
Centeno Tablante E, Pachon H, Guetterman HM, et al. Fortification of wheat and maize flour with folic acid for population health outcomes. Cochrane Database Syst Rev 2019; 7:CD012150.
Hurrell RF. Fortification: overcoming technical and practical barriers. J Nutr 2002; 132: (4 Suppl): 806S–S812.
Rahman AS, Ahmed T, Ahmed F, et al. Double-blind cluster randomised controlled trial of wheat flour chapatti fortified with micronutrients on the status of vitamin A and iron in school-aged children in rural Bangladesh. Matern Child Nutr 2015; 11: (Suppl 4): 120–131.
Hombali AS, Solon JA, Venkatesh BT, et al. Fortification of staple foods with vitamin A for vitamin A deficiency. Cochrane Database Syst Rev 2019; 5:CD010068.
Mendu VVR, Nair KPM, Athe R. Systematic review and meta-analysis approach on vitamin A fortified foods and its effect on retinol concentration in under 10 year children. Clin Nutr ESPEN 2019; 30:126–130.
Brandao-Lima PN, Santos BDC, Aguilera CM, et al. Vitamin D food fortification and nutritional status in children: a systematic review of randomized controlled trials. Nutrients 2019; 11: doi: 10.3390/nu11112766 [published Online First: 2019/11/20].
doi: 10.3390/nu11112766
Benjeddou K, Qandoussi L, Mekkaoui B, et al. Effect of multiple micronutrient fortified milk consumption on vitamin D status among school-aged children in rural region of Morocco. Appl Physiol Nutr Metab 2019; 44:461–467.
Wassie MM, Yelland LN, Smithers LG, et al. Comparison of iodine status pre and postmandatory iodine fortification of bread in South Australia: a population study using newborn thyroid-stimulating hormone concentration as a marker. Public Health Nutr 2019; 22:3063–3072.
Das JK, Salam RA, Mahmood SB, et al. Food fortification with multiple micronutrients: impact on health outcomes in general population. Cochrane Database Syst Rev 2019; 12:CD011400.
Santos JAR, Christoforou A, Trieu K, et al. Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders. Cochrane Database Syst Rev 2019; 2:CD010734.
D’Antoine H, Bower C. Folate status and neural tube defects in aboriginal Australians: the success of mandatory fortification in reducing a health disparity. Curr Dev Nutr 2019; 3:nzz071.
Keats EC, Neufeld LM, Garrett GS, et al. Improved micronutrient status and health outcomes in low- and middle-income countries following large-scale fortification: evidence from a systematic review and meta-analysis. Am J Clin Nutr 2019; 109:1696–1708.
Sadighi J, Nedjat S, Rostami R. Systematic review and meta-analysis of the effect of iron-fortified flour on iron status of populations worldwide. Public Health Nutr 2019; 22:3465–3484.
Siegel RL, Miller KD, Jemal A. Cancer statistics. CA Cancer J Clin 2019; 69:7–34.
Pena-Rosas JP, Mithra P, Unnikrishnan B, et al. Fortification of rice with vitamins and minerals for addressing micronutrient malnutrition. Cochrane Database Syst Rev 2019; 2019:CD009902.
WHO/CDC. Logic model for micronutrient interventions in public health Geneva (Switzerland): WHO; 2016. Available from: https://apps.who.int/iris/bitstream/handle/10665/250746/WHO-NMH-NHD-EPG-16.1-colour-eng.pdf;jsessionid=C5BE1E1FA28E2977AAAA0C06C48175CB?sequence=3 [Accessed 8 January 2021]
Mkambula P, Mbuya MNN, Rowe LA, et al. The unfinished agenda for food fortification in low- and middle-income countries: quantifying progress. Gaps and Potential Oppor Nutr 2020; 12:354.