Molecular epidemiological characteristics of echovirus 6 in mainland China: extensive circulation of genotype F from 2007 to 2018.


Journal

Archives of virology
ISSN: 1432-8798
Titre abrégé: Arch Virol
Pays: Austria
ID NLM: 7506870

Informations de publication

Date de publication:
May 2021
Historique:
received: 03 07 2020
accepted: 04 11 2020
pubmed: 28 2 2021
medline: 20 4 2021
entrez: 27 2 2021
Statut: ppublish

Résumé

Echovirus 6 (E6) is associated with various clinical diseases and is frequently detected in environmental sewage. Despite its high prevalence in humans and the environment, little is known about its molecular phylogeography in mainland China. In this study, 114 of 21,539 (0.53%) clinical specimens from hand, foot, and mouth disease (HFMD) cases collected between 2007 and 2018 were positive for E6. The complete VP1 sequences of 87 representative E6 strains, including 24 strains from this study, were used to investigate the evolutionary genetic characteristics and geographical spread of E6 strains. Phylogenetic analysis based on VP1 nucleotide sequence divergence showed that, globally, E6 strains can be grouped into six genotypes, designated A to F. Chinese E6 strains collected between 1988 and 2018 were found to belong to genotypes C, E, and F, with genotype F being predominant from 2007 to 2018. There was no significant difference in the geographical distribution of each genotype. The evolutionary rate of E6 was estimated to be 3.631 × 10

Identifiants

pubmed: 33638089
doi: 10.1007/s00705-020-04934-7
pii: 10.1007/s00705-020-04934-7
pmc: PMC8036204
doi:

Substances chimiques

Capsid Proteins 0
RNA, Viral 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1305-1312

Subventions

Organisme : Key Technologies Research and Development Program (CN)
ID : 2018ZX10201002-003-003

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Auteurs

Wenjun Cheng (W)

Medical School, Anhui University of Science and Technology, Huainan, 232001, Anhui, People's Republic of China.
NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.

Tianjiao Ji (T)

NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.

Shuaifeng Zhou (S)

Hunan Provincial Centers for Disease Control and Prevention, Changsha, People's Republic of China.

Yong Shi (Y)

Jiangxi Provincial Centers for Disease Control and Prevention, Nanchang, People's Republic of China.

Lili Jiang (L)

Yunnan Provincial Centers for Disease Control and Prevention, Kunming, People's Republic of China.

Yong Zhang (Y)

NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.

Dongmei Yan (D)

NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.

Qian Yang (Q)

NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.

Yang Song (Y)

NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.

Ru Cai (R)

Medical School, Anhui University of Science and Technology, Huainan, 232001, Anhui, People's Republic of China. lxhcrlh@aliyun.com.

Wenbo Xu (W)

Medical School, Anhui University of Science and Technology, Huainan, 232001, Anhui, People's Republic of China. wenbo_xu1@aliyun.com.
NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China. wenbo_xu1@aliyun.com.

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Classifications MeSH