Blood alcohol levels in Finnish victims of non-ischaemic sudden cardiac death.
Alcohol
medico-legal autopsy
non-ischaemic heart disease
sudden cardiac death
Journal
Annals of medicine
ISSN: 1365-2060
Titre abrégé: Ann Med
Pays: England
ID NLM: 8906388
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
entrez:
1
3
2021
pubmed:
2
3
2021
medline:
15
12
2021
Statut:
ppublish
Résumé
Non-ischaemic heart disease (NIHD) is the underlying pathology in∼20% of all sudden cardiac deaths (SCDs). Heavy drinking is known to be associated with SCD due to ischaemic heart disease, but studies on association of recent alcohol consumption and SCD in patients with NIHD are scarce. We evaluated the blood alcohol levels of autopsy verified non-ischaemic SCD victims. Study population was derived from the Finnish Genetic Study of Arrhythmic Events (Fingesture) ( A total of 1301 (mean age 57 ± 12, 78% males) victims of SCD due to NIHD were included in the study. The blood ethanol level was elevated in 543 (42%) subjects, out of which the blood alcohol level was ≥0.10%in 339 (62%) subjects and ≥0.15%in 252 (46%) subjects. Male SCD victims had alcohol in blood more frequently compared to females (45% versus 31%, Elevated blood alcohol level is common in SCD victims due to NIHD, especially in males. Recent alcohol consumption might contribute to the subsequent SCD in many non-ischaemic SCD victims.KEY MESSAGESElevated blood alcohol level is common in victims of sudden cardiac death due to non-ischaemic heart disease, especially in males.Recent alcohol consumption may contribute to the subsequent death in many nonischemic sudden cardiac death victims.
Identifiants
pubmed: 33645352
doi: 10.1080/07853890.2021.1890204
pmc: PMC7928009
doi:
Substances chimiques
Alcohols
0
Blood Alcohol Content
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
413-419Références
Forensic Sci Int. 2011 Oct 10;212(1-3):121-5
pubmed: 21708436
Drug Test Anal. 2019 Sep;11(9):1326-1337
pubmed: 31128576
Resuscitation. 2011 Jul;82(7):825-9
pubmed: 21450387
Am J Cardiol. 2005 Aug 1;96(3):346-51
pubmed: 16054455
Circulation. 2005 Dec 20;112(25):3839-45
pubmed: 16365208
Heart Rhythm. 2011 Oct;8(10):1570-5
pubmed: 21740887
Europace. 2016 Jul;18(7):1006-9
pubmed: 26552693
Alcohol. 1984 Jul-Aug;1(4):333-9
pubmed: 6399213
Arch Pathol Lab Med. 2017 Sep;141(9):1262-1266
pubmed: 28657772
Circulation. 2019 Feb 19;139(8):1012-1021
pubmed: 30779638
Compr Physiol. 2015 Apr;5(2):791-802
pubmed: 25880513
Arq Bras Cardiol. 2014 Oct;103(4):348-57
pubmed: 25352509
Eur J Intern Med. 2017 Sep;43:1-5
pubmed: 28647343
BMJ. 2011 Feb 22;342:d671
pubmed: 21343207
J Am Coll Cardiol. 2000 Jun;35(7):1753-9
pubmed: 10841221
J Stud Alcohol. 2000 Jul;61(4):507-14
pubmed: 10928720
Int J Legal Med. 2015 Jan;129(1):89-96
pubmed: 25399050
Drug Test Anal. 2014 Apr;6(4):308-16
pubmed: 23881890
Resuscitation. 2005 Oct;67(1):51-4
pubmed: 16146670
Addiction. 2017 Feb;112(2):207-214
pubmed: 27316346
Br Heart J. 1992 Nov;68(5):443-8
pubmed: 1467026
Circulation. 2002 Mar 26;105(12):1453-8
pubmed: 11914254
Chest. 2002 May;121(5):1638-50
pubmed: 12006456
Med Hypotheses. 2016 Feb;87:11-3
pubmed: 26826633
N Engl J Med. 2004 May 20;350(21):2151-8
pubmed: 15152060
Circ Res. 2017 Sep 15;121(7):711-721
pubmed: 28912178