Performance evaluation of a fully closed real-time PCR platform for the detection of KRAS p.G12C mutations in liquid biopsy of patients with non-small cell lung cancer.


Journal

Journal of clinical pathology
ISSN: 1472-4146
Titre abrégé: J Clin Pathol
Pays: England
ID NLM: 0376601

Informations de publication

Date de publication:
May 2022
Historique:
received: 13 01 2021
revised: 08 02 2021
accepted: 09 02 2021
pubmed: 3 3 2021
medline: 23 4 2022
entrez: 2 3 2021
Statut: ppublish

Résumé

Whenever tissue sample is not available, non-small cell lung cancer (NSCLC) biomarker testing is performed with liquid biopsy. The Kirsten rat sarcoma viral oncogene homolog (

Identifiants

pubmed: 33649142
pii: jclinpath-2021-207416
doi: 10.1136/jclinpath-2021-207416
doi:

Substances chimiques

Cell-Free Nucleic Acids 0
KRAS protein, human 0
Proto-Oncogene Proteins p21(ras) EC 3.6.5.2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

350-353

Informations de copyright

© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: GT reports personal fees (as speaker bureau or advisor) from Roche, MSD, Pfizer and Bayer, unrelated to the current work. UM received personal fees (as consultant and/or speaker bureau) from Boehringer Ingelheim, Roche, MSD, Amgen, Thermo Fisher Scientifics, Diaceutics, GSK, Merck and AstraZeneca, unrelated to the current work. The other authors have no other conflicts of interest to declare.

Auteurs

Gianluca Gragnano (G)

Public Health, University of Naples Federico II, Naples, Italy.

Mariantonia Nacchio (M)

Public Health, University of Naples Federico II, Naples, Italy.

Roberta Sgariglia (R)

Public Health, University of Naples Federico II, Naples, Italy.

Floriana Conticelli (F)

Public Health, University of Naples Federico II, Naples, Italy.

Antonino Iaccarino (A)

Public Health, University of Naples Federico II, Naples, Italy.

Caterina De Luca (C)

Public Health, University of Naples Federico II, Naples, Italy.

Giancarlo Troncone (G)

Public Health, University of Naples Federico II, Naples, Italy giancarlo.troncone@unina.it.

Umberto Malapelle (U)

Public Health, University of Naples Federico II, Naples, Italy.

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Classifications MeSH