Sustained growth of intraosseous hormone-associated meningiomas after cessation of progestin therapy.
Meningioma
Natural history
Nomegestrol acetate
Primary brain tumor
Progestin
Wait-and-scan strategy
Journal
Acta neurochirurgica
ISSN: 0942-0940
Titre abrégé: Acta Neurochir (Wien)
Pays: Austria
ID NLM: 0151000
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
14
10
2020
accepted:
19
02
2021
pubmed:
3
3
2021
medline:
10
7
2021
entrez:
2
3
2021
Statut:
ppublish
Résumé
Hormone-associated meningiomas tend to stop growing or decrease in size after cessation of certain progestins, mainly cyproterone acetate. We report three observations on the natural history of hormone-associated intraosseous meningiomas, showing in a first patient that those tumors may grow rapidly under nomegestrol. We then demonstrate the sustained growth of intraosseous hormone-associated meningiomas after cessation of promesgestone and nomegestrol, independently of the intracranial portion, which concurrently decreased in size in the second case or was resected at the time of nomegestrol withdrawal in the third case, thus giving new insights into the tumorigenesis mechanisms of hormone-associated intraosseous meningiomas.
Identifiants
pubmed: 33649877
doi: 10.1007/s00701-021-04781-8
pii: 10.1007/s00701-021-04781-8
doi:
Substances chimiques
Progestins
0
nomegestrol
10F89177CO
Cyproterone Acetate
4KM2BN5JHF
Megestrol
EA6LD1M70M
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1705-1710Références
Behbahani M, Skeie GO, Eide GE, Hausken A, Lund-Johansen M, Skeie BS (2019) A prospective study of the natural history of incidental meningioma-Hold your horses! Neuro-Oncol Pract 6(6):438–450
doi: 10.1093/nop/npz011
Bernat AL, Oyama K, Hamdi S, Mandonnet E, Vexiau D, Pocard M, George B, Froelich S (2015) Growth stabilization and regression of meningiomas after discontinuation of cyproterone acetate: a case series of 12 patients. Acta Neurochir (Wien) 157(10):1741–1746
doi: 10.1007/s00701-015-2532-3
Bikmaz K, Mrak R, Al-Mefty O (2007) Management of bone-invasive, hyperostotic sphenoid wing meningiomas. J Neurosurg 107(5):905–912
doi: 10.3171/JNS-07/11/0905
Butscheidt S, Ernst M, Rolvien T, Hubert J, Zustin J, Amling M, Martens T (2019) Primary intraosseous meningioma: clinical, histological, and differential diagnostic aspects. J Neurosurg 1–10
Clark VE, Erson-Omay EZ, Serin A et al (2013) Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science 339(6123):1077–1080
doi: 10.1126/science.1233009
Cushing H, Eisenhardt L (1938) Meningiomas. Their classification, regional behaviour, life history and surgical end results. Thomas, Springfield
De Jesús O, Toledo M (2001) Surgical management of meningioma en plaque of the sphenoid ridge. Surg Neurol 55(5):265–269
doi: 10.1016/S0090-3019(01)00440-2
Di Cristofori A, Del Bene M, Locatelli M, Boggio F, Ercoli G, Ferrero S, Del Gobbo A (2018) Meningioma and bone hyperostosis: expression of bone stimulating factors and review of the literature. World Neurosurg 115:e774–e781
doi: 10.1016/j.wneu.2018.04.176
Gupta SK, Mohindra S, Radotra BD, Khosla VK (2006) Giant calvarial hyperostosis with biparasagittal en plaque meningioma. Neurol India 54(2):210–212
pubmed: 16804274
Ho C-Y, Mosier S, Safneck J, Salomao DR, Miller NR, Eberhart CG, Gocke CD, Batista DAS, Rodriguez FJ (2015) Genetic profiling by single-nucleotide polymorphism-based array analysis defines three distinct subtypes of orbital meningioma. Brain Pathol 25(2):193–201
doi: 10.1111/bpa.12150
Kalamarides M, Peyre M (2017) Dramatic shrinkage with reduced vascularization of large meningiomas after cessation of progestin treatment. World Neurosurg 101:814.e7–814.e10
doi: 10.1016/j.wneu.2017.03.013
Kumaria A, Ingale HA, Macarthur DC (2018) Spontaneous regression of a large skull base meningioma: case report. Br J Neurosurg 34(2):205–206
doi: 10.1080/02688697.2018.1426728
Passeri T, Champagne C, Bernat A, Hanakita S, Salle H, Mandonnet E, Froelich S (2019) Spontaneous regression of meningiomas after interruption of nomegestrol acetate: a series of three patients. Acta Neurochir (Wien) 161(4):761–765
doi: 10.1007/s00701-019-03848-x
Pei J, Jung S, Jin S-G et al (2012) Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas. Acta Neurochir (Wien) 154(4):611–620 discussion 620
doi: 10.1007/s00701-012-1289-1
Pieper DR, Al-Mefty O, Hanada Y, Buechner D (1999) Hyperostosis associated with meningioma of the cranial base: secondary changes or tumor invasion. Neurosurgery 44(4):742–746 discussion 746–747
doi: 10.1097/00006123-199904000-00028
Shimizu J, Matsumoto M, Yamazaki E, Yasue M (2008) Spontaneous regression of an asymptomatic meningioma associated with discontinuation of progesterone agonist administration. Neurol Med Chir (Tokyo) 48(5):227–230
doi: 10.2176/nmc.48.227
Talacchi A, Corsini F, Gerosa M (2011) Hyperostosing meningiomas of the cranial vault with and without tumor mass. Acta Neurochir (Wien) 153(1):53–61 discussion 61
doi: 10.1007/s00701-010-0838-8
Vadivelu S, Sharer L, Schulder M Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy. J Neurosurg 112(5):920–924
Weill A, Cadier B, Nguyen P, Coste J (2019) Exposition prolongée à de fortes doses d’acétate de cyprotérone et risque de méningiome chez la femme. Etude pharmaco-épidémiologique de cohorte à partir des données du SNDS
Yoneoka Y, Fujii Y, Tanaka R (2000) Growth of incidental meningiomas. Acta Neurochir (Wien) 142(5):507–511
doi: 10.1007/s007010050463