Pulmonary fibrosis in Fra-2 transgenic mice is associated with decreased numbers of alveolar macrophages and increased susceptibility to pneumococcal pneumonia.

Animals Cytokines / genetics Disease Models, Animal Disease Susceptibility Fos-Related Antigen-2 / genetics Macrophages, Alveolar / metabolism Mice Mice, Transgenic Pneumonia, Pneumococcal / genetics Pulmonary Fibrosis / genetics Streptococcus pneumoniae / metabolism
Streptococcus pneumoniae bacteremia idiopathic pulmonary fibrosis lung fibrosis pneumonia

Journal

American journal of physiology. Lung cellular and molecular physiology
ISSN: 1522-1504
Titre abrégé: Am J Physiol Lung Cell Mol Physiol
Pays: United States
ID NLM: 100901229

Informations de publication

Date de publication:
01 05 2021
Historique:
pubmed: 4 3 2021
medline: 28 7 2021
entrez: 3 3 2021
Statut: ppublish

Résumé

Idiopathic pulmonary fibrosis (IPF) is a deadly condition characterized by progressive respiratory dysfunction. Exacerbations due to airway infections are believed to promote disease progression, and presence of

Identifiants

DOI: 10.1152/ajplung.00505.2020 PMID: 33655757
pubmed: 33655757
doi: 10.1152/ajplung.00505.2020
doi:

Substances chimiques

Cytokines 0
Fos-Related Antigen-2 0
Fosl2 protein, mouse 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

L916-L925

Auteurs

Christoph Tabeling (C)

Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.
ORCID: 0000-0001-9189-4318

Sandra-Maria Wienhold (SM)

Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
ORCID: 0000-0001-5655-4350

Anna Birnhuber (A)

Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
ORCID: 0000-0002-8358-8377

Markus C Brack (MC)

Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

Geraldine Nouailles (G)

Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
ORCID: 0000-0003-1973-3119

Olivia Kershaw (O)

Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.

Theresa C Firsching (TC)

Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
ORCID: 0000-0003-1378-4951

Achim D Gruber (AD)

Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.

Jasmin Lienau (J)

Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

Leigh M Marsh (LM)

Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
ORCID: 0000-0002-1754-9249

Andrea Olschewski (A)

Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.

Grazyna Kwapiszewska (G)

Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Otto Loewi Research Center, Medical University of Graz, Graz, Austria.

Martin Witzenrath (M)

Division of Pulmonary Inflammation, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
German Center for Lung Research (DZL), Partner Site Charité, Berlin, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Prédisposition aux maladies › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique et à glissière à leucines › Antigène-2 apparenté à fos › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Macrophages alvéolaires › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie bactérienne › Pneumonie à pneumocoques › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Fibrose pulmonaire › Pulmonary fibrosis in Fra-2 transgenic mice is...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pneumoniae › Pulmonary fibrosis in Fra-2 transgenic mice is...