Geraldine Nouailles

Affiliations

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany. Electronic address: geraldine.nouailles@charite.de.

Publications (24)

Protocol to dissociate healthy and infected murine- and hamster-derived lung tissue for single-cell transcriptome analysis.

STAR protocols

Avec: Peter Pennitz , Cengiz Goekeri , Jakob Trimpert , Emanuel Wyler , Aileen Ebenig , Chantal Weissfuss , Michael D Mühlebach , Martin Witzenrath , Geraldine Nouailles

IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Ivo Röwekamp , Laura Maschirow , Anne Rabes , Facundo Fiocca Vernengo , Lutz Hamann , Gitta Anne Heinz , Mir-Farzin Mashreghi , Sandra Caesar , Miha Milek , Anna Carolina Fagundes Fonseca , Sandra-Maria Wienhold , Geraldine Nouailles , Ling Yao , Soraya Mousavi , Dunja Bruder , Julia D Boehme , Monika Puzianowska-Kuznicka , Dieter Beule , Martin Witzenrath , Auteur inconnu , Max Löhning , Christoph S N Klose , Markus M Heimesaat , Andreas Diefenbach , Bastian Opitz

Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to

mBio

Avec: Natalie E Nieuwenhuizen , Geraldine Nouailles , Jayne S Sutherland , Joanna Zyla , Arja H Pasternack , Jan Heyckendorf , Björn C Frye , Kerstin Höhne , Ulrike Zedler , Silke Bandermann , Ulrike Abu Abed , Volker Brinkmann , Birgitt Gutbier , Martin Witzenrath , Norbert Suttorp , Gernot Zissel , Christoph Lange , Olli Ritvos , Stefan H E Kaufmann , Auteur inconnu , Auteur inconnu

Preclinical Assessment of Bacteriophage Therapy against Experimental

Viruses

Avec: Sandra-Maria Wienhold , Markus C Brack , Geraldine Nouailles , Gopinath Krishnamoorthy , Imke H E Korf , Claudius Seitz , Sarah Wienecke , Kristina Dietert , Corinne Gurtner , Olivia Kershaw , Achim D Gruber , Anton Ross , Holger Ziehr , Manfred Rohde , Jens Neudecker , Jasmin Lienau , Norbert Suttorp , Stefan Hippenstiel , Andreas C Hocke , Christine Rohde , Martin Witzenrath

A biomathematical model of atherosclerosis in mice.

PloS one

Avec: Sibylle Schirm , Arash Haghikia , Markus Brack , Peter Ahnert , Geraldine Nouailles , Norbert Suttorp , Markus Loeffler , Martin Witzenrath , Markus Scholz

MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia.

Cells

Avec: Cengiz Goekeri , Peter Pennitz , Wibke Groenewald , Ulrike Behrendt , Holger Kirsten , Christian M Zobel , Sarah Berger , Gitta A Heinz , Mir-Farzin Mashreghi , Sandra-Maria Wienhold , Kristina Dietert , Anca Dorhoi , Achim D Gruber , Markus Scholz , Gernot Rohde , Norbert Suttorp , Capnetz Study Group , Martin Witzenrath , Geraldine Nouailles

On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx.

International journal of molecular sciences

Avec: Matthias Ochs , Jan Hegermann , Elena Lopez-Rodriguez , Sara Timm , Geraldine Nouailles , Jasmin Matuszak , Szandor Simmons , Martin Witzenrath , Wolfgang M Kuebler

Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for

Frontiers in immunology

Avec: Frida Arrey , Delia Löwe , Stefanie Kuhlmann , Peggy Kaiser , Pedro Moura-Alves , Gopinath Krishnamoorthy , Laura Lozza , Jeroen Maertzdorf , Tatsiana Skrahina , Alena Skrahina , Martin Gengenbacher , Geraldine Nouailles , Stefan H E Kaufmann

A biomathematical model of immune response and barrier function in mice with pneumococcal lung infection.

PloS one

Avec: Sibylle Schirm , Peter Ahnert , Sarah Berger , Geraldine Nouailles , Sandra-Maria Wienhold , Holger Müller-Redetzky , Norbert Suttorp , Markus Loeffler , Martin Witzenrath , Markus Scholz

Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice.

Scientific reports

Avec: Aina Lask , Birgitt Gutbier , Olivia Kershaw , Geraldine Nouailles , Achim D Gruber , Holger C Müller-Redetzky , Steven Chackowicz , Douglas A Hamilton , Paul Van Slyke , Martin Witzenrath

Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.

Nature communications

Avec: Geraldine Nouailles , Emanuel Wyler , Peter Pennitz , Dylan Postmus , Daria Vladimirova , Julia Kazmierski , Fabian Pott , Kristina Dietert , Michael Muelleder , Vadim Farztdinov , Benedikt Obermayer , Sandra-Maria Wienhold , Sandro Andreotti , Thomas Hoefler , Birgit Sawitzki , Christian Drosten , Leif E Sander , Norbert Suttorp , Markus Ralser , Dieter Beule , Achim D Gruber , Christine Goffinet , Markus Landthaler , Jakob Trimpert , Martin Witzenrath

An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission.

Nature communications

Avec: Julia M Adler , Ricardo Martin Vidal , Christine Langner , Daria Vladimirova , Azza Abdelgawad , Daniela Kunecova , Xiaoyuan Lin , Geraldine Nouailles , Anne Voss , Sandra Kunder , Achim D Gruber , Haibo Wu , Nikolaus Osterrieder , Dusan Kunec , Jakob Trimpert

Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T

Cell reports

Avec: Aileen Ebenig , Samada Muraleedharan , Julia Kazmierski , Daniel Todt , Arne Auste , Martina Anzaghe , André Gömer , Dylan Postmus , Patricia Gogesch , Marc Niles , Roland Plesker , Csaba Miskey , Michelle Gellhorn Serra , Angele Breithaupt , Cindy Hörner , Carina Kruip , Rosina Ehmann , Zoltan Ivics , Zoe Waibler , Stephanie Pfaender , Emanuel Wyler , Markus Landthaler , Alexandra Kupke , Geraldine Nouailles , Christine Goffinet , Richard J P Brown , Michael D Mühlebach

Repetitive Exposure to Bacteriophage Cocktails against

Viruses

Avec: Chantal Weissfuss , Sandra-Maria Wienhold , Magdalena Bürkle , Baptiste Gaborieau , Judith Bushe , Ulrike Behrendt , Romina Bischoff , Imke H E Korf , Sarah Wienecke , Antonia Dannheim , Holger Ziehr , Christine Rohde , Achim D Gruber , Jean-Damien Ricard , Laurent Debarbieux , Martin Witzenrath , Geraldine Nouailles

The unremarkable alveolar epithelial glycocalyx: a thorium dioxide-based electron microscopic comparison after heparinase or pneumolysin treatment.

Histochemistry and cell biology

Avec: Sara Timm , Marie Lettau , Jan Hegermann , Maria Linda Rocha , Sarah Weidenfeld , Diana Fatykhova , Birgitt Gutbier , Geraldine Nouailles , Elena Lopez-Rodriguez , Andreas Hocke , Stefan Hippenstiel , Martin Witzenrath , Wolfgang M Kuebler , Matthias Ochs

Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease.

EBioMedicine

Avec: Vincent D Friedrich , Peter Pennitz , Emanuel Wyler , Julia M Adler , Dylan Postmus , Kristina Müller , Luiz Gustavo Teixeira Alves , Julia Prigann , Fabian Pott , Daria Vladimirova , Thomas Hoefler , Cengiz Goekeri , Markus Landthaler , Christine Goffinet , Antoine-Emmanuel Saliba , Markus Scholz , Martin Witzenrath , Jakob Trimpert , Holger Kirsten , Geraldine Nouailles

Pulmonary fibrosis in Fra-2 transgenic mice is associated with decreased numbers of alveolar macrophages and increased susceptibility to pneumococcal pneumonia.

American journal of physiology. Lung cellular and molecular physiology

Avec: Christoph Tabeling , Sandra-Maria Wienhold , Anna Birnhuber , Markus C Brack , Geraldine Nouailles , Olivia Kershaw , Theresa C Firsching , Achim D Gruber , Jasmin Lienau , Leigh M Marsh , Andrea Olschewski , Grazyna Kwapiszewska , Martin Witzenrath

Pneumolysin induces platelet destruction, not platelet activation, which can be prevented by immunoglobulin preparations in vitro.

Blood advances

Avec: Kristin Jahn , Stefan Handtke , Raghavendra Palankar , Sabrina Weißmüller , Geraldine Nouailles , Thomas P Kohler , Jan Wesche , Manfred Rohde , Corina Heinz , Axel F Aschenbrenner , Martina Wolff , Jörg Schüttrumpf , Martin Witzenrath , Sven Hammerschmidt , Andreas Greinacher

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Emanuel Wyler , Julia M Adler , Kathrin Eschke , G Teixeira Alves , Stefan Peidli , Fabian Pott , Julia Kazmierski , Laura Michalick , Olivia Kershaw , Judith Bushe , Sandro Andreotti , Peter Pennitz , Azza Abdelgawad , Dylan Postmus , Christine Goffinet , Jakob Kreye , S Momsen Reincke , Harald Prüss , Nils Blüthgen , Achim D Gruber , Wolfgang M Kuebler , Martin Witzenrath , Markus Landthaler , Geraldine Nouailles , Jakob Trimpert

A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics.

European respiratory review : an official journal of the European Respiratory Society

Avec: Peter Pennitz , Holger Kirsten , Vincent D Friedrich , Emanuel Wyler , Cengiz Goekeri , Benedikt Obermayer , Gitta A Heinz , Mir-Farzin Mashreghi , Maren Büttner , Jakob Trimpert , Markus Landthaler , Norbert Suttorp , Andreas C Hocke , Stefan Hippenstiel , Mario Tönnies , Markus Scholz , Wolfgang M Kuebler , Martin Witzenrath , Katja Hoenzke , Geraldine Nouailles

De Novo-Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome: An Animal Model for Severe/Critical COVID-19.

Genome biology and evolution

Avec: Sandro Andreotti , Janine Altmüller , Claudia Quedenau , Tatiana Borodina , Geraldine Nouailles , Luiz Gustavo Teixeira Alves , Markus Landthaler , Maximilian Bieniara , Jakob Trimpert , Emanuel Wyler

Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.

Nature microbiology

Avec: Geraldine Nouailles , Julia M Adler , Peter Pennitz , Stefan Peidli , Luiz Gustavo Teixeira Alves , Morris Baumgardt , Judith Bushe , Anne Voss , Alina Langenhagen , Christine Langner , Ricardo Martin Vidal , Fabian Pott , Julia Kazmierski , Aileen Ebenig , Mona V Lange , Michael D Mühlebach , Cengiz Goekeri , Szandor Simmons , Na Xing , Azza Abdelgawad , Susanne Herwig , Günter Cichon , Daniela Niemeyer , Christian Drosten , Christine Goffinet , Markus Landthaler , Nils Blüthgen , Haibo Wu , Martin Witzenrath , Achim D Gruber , Samantha D Praktiknjo , Nikolaus Osterrieder , Emanuel Wyler , Dusan Kunec , Jakob Trimpert

Enzymatic Modulation of the Pulmonary Glycocalyx Enhances Susceptibility to

American journal of respiratory cell and molecular biology

Avec: Cengiz Goekeri , Kerstin A K Linke , Karen Hoffmann , Elena Lopez-Rodriguez , Vladimir Gluhovic , Anne Voß , Sandra Kunder , Andreas Zappe , Sara Timm , Alina Nettesheim , Sebastian M K Schickinger , Christian M Zobel , Kevin Pagel , Achim D Gruber , Matthias Ochs , Martin Witzenrath , Geraldine Nouailles

Single-cell-resolved interspecies comparison shows a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19.

Cell reports

Avec: Stefan Peidli , Geraldine Nouailles , Emanuel Wyler , Julia M Adler , Sandra Kunder , Anne Voß , Julia Kazmierski , Fabian Pott , Peter Pennitz , Dylan Postmus , Luiz Gustavo Teixeira Alves , Christine Goffinet , Achim D Gruber , Nils Blüthgen , Martin Witzenrath , Jakob Trimpert , Markus Landthaler , Samantha D Praktiknjo

Réseau de co-auteurs

Martin Witzenrath 20 collaborations

Achim D Gruber 11 collaborations

Jakob Trimpert 9 collaborations

Emanuel Wyler 9 collaborations

Peter Pennitz 8 collaborations

Markus Landthaler 8 collaborations

Sandra-Maria Wienhold 7 collaborations

Norbert Suttorp 7 collaborations

Cengiz Goekeri 6 collaborations

Christine Goffinet 6 collaborations

Markus Scholz 5 collaborations

Dylan Postmus 5 collaborations

Julia Kazmierski 5 collaborations

Fabian Pott 5 collaborations

Julia M Adler 5 collaborations

Olivia Kershaw 4 collaborations

Wolfgang M Kuebler 4 collaborations

Luiz Gustavo Teixeira Alves 4 collaborations

Aileen Ebenig 3 collaborations

Michael D Mühlebach 3 collaborations

Mir-Farzin Mashreghi 3 collaborations

None None 3 collaborations

Birgitt Gutbier 3 collaborations

Kristina Dietert 3 collaborations

Stefan Hippenstiel 3 collaborations

Holger Kirsten 3 collaborations

Matthias Ochs 3 collaborations

Elena Lopez-Rodriguez 3 collaborations

Sara Timm 3 collaborations

Daria Vladimirova 3 collaborations

Sandro Andreotti 3 collaborations

Azza Abdelgawad 3 collaborations

Sandra Kunder 3 collaborations

Judith Bushe 3 collaborations

Stefan Peidli 3 collaborations

Nils Blüthgen 3 collaborations

Chantal Weissfuss 2 collaborations

Dieter Beule 2 collaborations

Stefan H E Kaufmann 2 collaborations

Markus C Brack 2 collaborations

Gopinath Krishnamoorthy 2 collaborations

Imke H E Korf 2 collaborations

Sarah Wienecke 2 collaborations

Holger Ziehr 2 collaborations

Manfred Rohde 2 collaborations

Jasmin Lienau 2 collaborations

Andreas C Hocke 2 collaborations

Christine Rohde 2 collaborations

Sibylle Schirm 2 collaborations

Peter Ahnert 2 collaborations

Markus Loeffler 2 collaborations

Ulrike Behrendt 2 collaborations

Christian M Zobel 2 collaborations

Sarah Berger 2 collaborations

Gitta A Heinz 2 collaborations

Jan Hegermann 2 collaborations

Szandor Simmons 2 collaborations

Benedikt Obermayer 2 collaborations

Thomas Hoefler 2 collaborations

Christian Drosten 2 collaborations

Ricardo Martin Vidal 2 collaborations

Christine Langner 2 collaborations

Anne Voss 2 collaborations

Haibo Wu 2 collaborations

Nikolaus Osterrieder 2 collaborations

Dusan Kunec 2 collaborations

Vincent D Friedrich 2 collaborations

Samantha D Praktiknjo 2 collaborations

Anne Voß 2 collaborations

Ivo Röwekamp 1 collaboration

Laura Maschirow 1 collaboration

Anne Rabes 1 collaboration

Facundo Fiocca Vernengo 1 collaboration

Lutz Hamann 1 collaboration

Gitta Anne Heinz 1 collaboration

Sandra Caesar 1 collaboration

Miha Milek 1 collaboration

Anna Carolina Fagundes Fonseca 1 collaboration

Ling Yao 1 collaboration

Soraya Mousavi 1 collaboration

Dunja Bruder 1 collaboration

Julia D Boehme 1 collaboration

Monika Puzianowska-Kuznicka 1 collaboration

Max Löhning 1 collaboration

Christoph S N Klose 1 collaboration

Markus M Heimesaat 1 collaboration

Andreas Diefenbach 1 collaboration

Bastian Opitz 1 collaboration

Natalie E Nieuwenhuizen 1 collaboration

Jayne S Sutherland 1 collaboration

Joanna Zyla 1 collaboration

Arja H Pasternack 1 collaboration

Jan Heyckendorf 1 collaboration

Björn C Frye 1 collaboration

Kerstin Höhne 1 collaboration

Ulrike Zedler 1 collaboration

Silke Bandermann 1 collaboration

Ulrike Abu Abed 1 collaboration

Volker Brinkmann 1 collaboration

Gernot Zissel 1 collaboration

Christoph Lange 1 collaboration

Olli Ritvos 1 collaboration

Claudius Seitz 1 collaboration

Corinne Gurtner 1 collaboration

Anton Ross 1 collaboration

Jens Neudecker 1 collaboration

Arash Haghikia 1 collaboration

Markus Brack 1 collaboration

Wibke Groenewald 1 collaboration

Anca Dorhoi 1 collaboration

Gernot Rohde 1 collaboration

None Capnetz Study Group 1 collaboration

Jasmin Matuszak 1 collaboration

Frida Arrey 1 collaboration

Delia Löwe 1 collaboration

Stefanie Kuhlmann 1 collaboration

Peggy Kaiser 1 collaboration

Pedro Moura-Alves 1 collaboration

Laura Lozza 1 collaboration

Jeroen Maertzdorf 1 collaboration

Tatsiana Skrahina 1 collaboration

Alena Skrahina 1 collaboration

Martin Gengenbacher 1 collaboration

Holger Müller-Redetzky 1 collaboration

Aina Lask 1 collaboration

Holger C Müller-Redetzky 1 collaboration

Steven Chackowicz 1 collaboration

Douglas A Hamilton 1 collaboration

Paul Van Slyke 1 collaboration

Michael Muelleder 1 collaboration

Vadim Farztdinov 1 collaboration

Birgit Sawitzki 1 collaboration

Leif E Sander 1 collaboration

Markus Ralser 1 collaboration

Daniela Kunecova 1 collaboration

Xiaoyuan Lin 1 collaboration

Samada Muraleedharan 1 collaboration

Daniel Todt 1 collaboration

Arne Auste 1 collaboration

Martina Anzaghe 1 collaboration

André Gömer 1 collaboration

Patricia Gogesch 1 collaboration

Marc Niles 1 collaboration

Roland Plesker 1 collaboration

Csaba Miskey 1 collaboration

Michelle Gellhorn Serra 1 collaboration

Angele Breithaupt 1 collaboration

Cindy Hörner 1 collaboration

Carina Kruip 1 collaboration

Rosina Ehmann 1 collaboration

Zoltan Ivics 1 collaboration

Zoe Waibler 1 collaboration

Stephanie Pfaender 1 collaboration

Alexandra Kupke 1 collaboration

Richard J P Brown 1 collaboration

Magdalena Bürkle 1 collaboration

Baptiste Gaborieau 1 collaboration

Romina Bischoff 1 collaboration

Antonia Dannheim 1 collaboration

Jean-Damien Ricard 1 collaboration

Laurent Debarbieux 1 collaboration

Marie Lettau 1 collaboration

Maria Linda Rocha 1 collaboration

Sarah Weidenfeld 1 collaboration

Diana Fatykhova 1 collaboration

Andreas Hocke 1 collaboration

Kristina Müller 1 collaboration

Julia Prigann 1 collaboration

Antoine-Emmanuel Saliba 1 collaboration

Christoph Tabeling 1 collaboration

Anna Birnhuber 1 collaboration

Theresa C Firsching 1 collaboration

Leigh M Marsh 1 collaboration

Andrea Olschewski 1 collaboration

Grazyna Kwapiszewska 1 collaboration

Kristin Jahn 1 collaboration

Stefan Handtke 1 collaboration

Raghavendra Palankar 1 collaboration

Sabrina Weißmüller 1 collaboration

Thomas P Kohler 1 collaboration

Jan Wesche 1 collaboration

Corina Heinz 1 collaboration

Axel F Aschenbrenner 1 collaboration

Martina Wolff 1 collaboration

Jörg Schüttrumpf 1 collaboration

Sven Hammerschmidt 1 collaboration

Andreas Greinacher 1 collaboration

Kathrin Eschke 1 collaboration

G Teixeira Alves 1 collaboration

Laura Michalick 1 collaboration

Jakob Kreye 1 collaboration

S Momsen Reincke 1 collaboration

Harald Prüss 1 collaboration

Maren Büttner 1 collaboration

Mario Tönnies 1 collaboration

Katja Hoenzke 1 collaboration

Janine Altmüller 1 collaboration

Claudia Quedenau 1 collaboration

Tatiana Borodina 1 collaboration

Maximilian Bieniara 1 collaboration

Morris Baumgardt 1 collaboration

Alina Langenhagen 1 collaboration

Mona V Lange 1 collaboration

Na Xing 1 collaboration

Susanne Herwig 1 collaboration

Günter Cichon 1 collaboration

Daniela Niemeyer 1 collaboration

Kerstin A K Linke 1 collaboration

Karen Hoffmann 1 collaboration

Vladimir Gluhovic 1 collaboration

Andreas Zappe 1 collaboration

Alina Nettesheim 1 collaboration

Sebastian M K Schickinger 1 collaboration

Kevin Pagel 1 collaboration