Jan Wesche

Affiliations

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

Publications (37)

The effect of deloading tape on medial gastrocnemius muscle fascicle behaviour during dynamic exercise.

Journal of sports sciences

Avec: Steven Obst , Luke Heales , Zachary Hrelja , Prashneveet Ishri , Johanna Wesche , Lee Barber

Role of Platelet Size Revisited-Function and Protein Composition of Large and Small Platelets.

Thrombosis and haemostasis

Avec: Stefan Handtke , Leif Steil , Raghavendra Palankar , Jane Conrad , Simran Cauhan , Luise Kraus , Myriam Ferrara , Vishnu Dhople , Jan Wesche , Uwe Völker , Andreas Greinacher , Thomas Thiele

Pneumolysin induces platelet destruction, not platelet activation, which can be prevented by immunoglobulin preparations in vitro.

Blood advances

Avec: Kristin Jahn , Stefan Handtke , Raghavendra Palankar , Sabrina Weißmüller , Geraldine Nouailles , Thomas P Kohler , Jan Wesche , Manfred Rohde , Corina Heinz , Axel F Aschenbrenner , Martina Wolff , Jörg Schüttrumpf , Martin Witzenrath , Sven Hammerschmidt , Andreas Greinacher

Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein.

Blood

Avec: Andreas Greinacher , Kathleen Selleng , Julia Mayerle , Raghavendra Palankar , Jan Wesche , Sven Reiche , Andrea Aebischer , Theodore E Warkentin , Maximilian Muenchhoff , Johannes C Hellmuth , Oliver T Keppler , Daniel Duerschmied , Achim Lother , Siegbert Rieg , Meinrad Paul Gawaz , Karin Anne Lydia Mueller , Christian S Scheer , Matthias Napp , Klaus Hahnenkamp , Guglielmo Lucchese , Antje Vogelgesang , Agnes Flöel , Piero Lovreglio , Angela Stufano , Rolf Marschalek , Thomas Thiele , Auteur inconnu

Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping.

Communications biology

Avec: Laura Sachs , Jan Wesche , Lea Lenkeit , Andreas Greinacher , Markus Bender , Oliver Otto , Raghavendra Palankar

Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure.

Blood

Avec: Linda Schönborn , Olga Esteban , Jan Wesche , Paulina Dobosz , Marta Broto , Sara Rovira Puig , Jessica Fuhrmann , Raquel Torres , Josep Serra , Roser Llevadot , Marta Palicio , Jing Jing Wang , Tom Paul Gordon , Edelgard Lindhoff-Last , Till Hoffmann , Lorenzo Alberio , Florian Langer , Christian Boehme , Eugenia Biguzzi , Leonie Grosse , Matthias Endres , Thomas G Liman , Thomas Thiele , Theodore E Warkentin , Andreas Greinacher

Activated platelets kill Staphylococcus aureus, but not Streptococcus pneumoniae-The role of FcγRIIa and platelet factor 4/heparinantibodies.

Journal of thrombosis and haemostasis : JTH

Avec: Martina Wolff , Stefan Handtke , Raghavendra Palankar , Jan Wesche , Thomas P Kohler , Christian Kohler , Yves Gruel , Sven Hammerschmidt , Andreas Greinacher

Self-reported health status and disease-specific quality of life one year after treatment for peripheral arterial disease in clinical practice.

Health and quality of life outcomes

Avec: Anne Sofie F Larsen , Anne Therese Reiersen , Inger Helene Nådland , Jarlis Wesche

A flow cytometric assay to detect platelet-activating antibodies in VITT after ChAdOx1 nCov-19 vaccination.

Blood

Avec: Stefan Handtke , Martina Wolff , Carlo Zaninetti , Jan Wesche , Linda Schönborn , Konstanze Aurich , Lena Ulm , Nils-Olaf Hübner , Karsten Becker , Thomas Thiele , Andreas Greinacher

Effect of Methylene Blue Pathogen Inactivation on the Integrity of Immunoglobulin M and G.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

Avec: Johannes Raster , Kathrin Zimmermann , Jan Wesche , Konstanze Aurich , Andreas Greinacher , Kathleen Selleng

α-hemolysin of Staphylococcus aureus impairs thrombus formation.

Journal of thrombosis and haemostasis : JTH

Avec: Kristin Jahn , Stefan Handtke , Raghavendra Palankar , Thomas P Kohler , Jan Wesche , Martina Wolff , Janina Bayer , Christiane Wolz , Andreas Greinacher , Sven Hammerschmidt

Divalent magnesium restores cytoskeletal storage lesions in cold-stored platelet concentrates.

Scientific reports

Avec: Konstanze Aurich , Jan Wesche , Martin Ulbricht , Oliver Otto , Andreas Greinacher , Raghavendra Palankar

Gas plasma-induced platelet activation corresponds to reactive species profiles and lipid oxidation.

Free radical biology & medicine

Avec: Johanna Striesow , Jan Wesche , Nicholas McKitterick , Larissa M Busch , Thomas von Woedtke , Andreas Greinacher , Sander Bekeschus , Kristian Wende

Indocyanine Green-Labeled Platelets for Survival and Recovery Studies.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

Avec: Johannes-Moritz von Behren , Jan Wesche , Andreas Greinacher , Konstanze Aurich

Pneumococcal neuraminidases increase platelet killing by pneumolysin.

Thrombosis and haemostasis

Avec: Kristin J Fritsch , Laura Krüger , Stefan Handtke , Thomas Peter Kohler , Arina Ozhiganova , Kristin Jahn , Jan Wesche , Andreas Greinacher , Sven Hammerschmidt

Reactivity of platelet-activating and nonplatelet-activating anti-PF4/heparin antibodies in enzyme immunosorbent assays under different conditions.

Journal of thrombosis and haemostasis : JTH

Avec: Thi-Huong Nguyen , Jan Wesche , Ricarda Raschke , Ulrike Strobel , Van-Chien Bui , Mihaela Delcea , Andreas Greinacher

Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway.

Cells

Avec: Patrycja Szybowska , Michal Kostas , Jørgen Wesche , Antoni Wiedlocha , Ellen Margrethe Haugsten

Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia.

Blood

Avec: Andreas Greinacher , Kathleen Selleng , Raghavendra Palankar , Jan Wesche , Stefan Handtke , Martina Wolff , Konstanze Aurich , Michael Lalk , Karen Methling , Uwe Völker , Christian Hentschker , Stephan Michalik , Leif Steil , Alexander Reder , Linda Schönborn , Martin Beer , Kati Franzke , Andreas Büttner , Boris Fehse , Evi X Stavrou , Chandini Rangaswamy , Reiner K Mailer , Hanna Englert , Maike Frye , Thomas Thiele , Stefan Kochanek , Lea Krutzke , Florian Siegerist , Nicole Endlich , Theodore E Warkentin , Thomas Renné

Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling.

Cells

Avec: Patrycja Szybowska , Michal Kostas , Jørgen Wesche , Ellen Margrethe Haugsten , Antoni Wiedlocha

Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1.

Cells

Avec: Aurora K Vikan , Michal Kostas , Ellen Margrethe Haugsten , Pål K Selbo , Jørgen Wesche

Comparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines.

Haematologica

Avec: Stephan Michalik , Florian Siegerist , Raghavendra Palankar , Kati Franzke , Maximilian Schindler , Alexander Reder , Ulrike Seifert , Clemens Cammann , Jan Wesche , Leif Steil , Christian Hentschker , Manuela Gesell-Salazar , Emil Reisinger , Martin Beer , Nicole Endlich , Andreas Greinacher , Uwe Völker

Group B Streptococcal Hemolytic Pigment Impairs Platelet Function in a Two-Step Process.

Cells

Avec: Kristin Jahn , Patience Shumba , Phoenicia Quach , Mathias Müsken , Jan Wesche , Andreas Greinacher , Lakshmi Rajagopal , Sven Hammerschmidt , Nikolai Siemens

FcγRIIA-specific DARPins as novel tools in blood cell analysis and platelet aggregation.

The Journal of biological chemistry

Avec: Vanessa Riechert , Sascha Hein , Mayken Visser , Mathias Zimmermann , Jan Wesche , Philipp A Adams , Samuel A Theuerkauf , Arezoo Jamali , Andrea Wangorsch , Andreas Reuter , Alexander O Pasternak , Jessica Hartmann , Andreas Greinacher , Elena Herrera-Carrillo , Ben Berkhout , Klaus Cichutek , Christian J Buchholz

Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma.

British journal of cancer

Avec: Elisa Fiorito , Patrycja Szybowska , Ellen M Haugsten , Michal Kostas , Geir F Øy , Antoni Wiedlocha , Sachin Singh , Sigve Nakken , Gunhild M Mælandsmo , Jonathan A Fletcher , Leonardo A Meza-Zepeda , Jørgen Wesche

Characterization and fungicide sensitivity of

Plant disease

Avec: Harleen Kaur , Johanna Wesche , Jhulia Gelain , Cai Minzheng , Chaoxi Luo , Guido Schnabel

A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation.

The Journal of biological chemistry

Avec: Dagim Shiferaw Tadele , Joseph Robertson , Richard Crispin , Maria C Herrera , Markéta Chlubnová , Laure Piechaczyk , Pilar Ayuda-Durán , Sachin Kumar Singh , Tobias Gedde-Dahl , Yngvar Fløisand , Jørn Skavland , Jørgen Wesche , Bjørn-Tore Gjertsen , Jorrit M Enserink

GAK and PRKCD are positive regulators of PRKN-independent mitophagy.

Nature communications

Avec: Michael J Munson , Benan J Mathai , Matthew Yoke Wui Ng , Laura Trachsel-Moncho , Laura R de la Ballina , Sebastian W Schultz , Yahyah Aman , Alf H Lystad , Sakshi Singh , Sachin Singh , Jørgen Wesche , Evandro F Fang , Anne Simonsen

Plant disease

Avec: Johanna Wesche , Zhezheng Zeng , Chaoxi Luo , Guido Schnabel

Quantitative interpretation of PF4/heparin-EIA optical densities in predicting platelet-activating VITT antibodies.

Journal of thrombosis and haemostasis : JTH

Avec: Linda Schönborn , Thomas Thiele , Max Esefeld , Khalil El Debuch , Jan Wesche , Sabrina E Seck , Lars Kaderali , Martina Wolff , Theodore E Warkentin , Andreas Greinacher

Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR.

International journal of cancer

Avec: Sigve Nakken , Sveinung Gundersen , Fabian L M Bernal , Dimitris Polychronopoulos , Eivind Hovig , Jørgen Wesche

Aggregates of non-muscular myosin IIA in erythrocytes associate with GATA1- and GFI1B-related thrombocytopenia.

Journal of thrombosis and haemostasis : JTH

Avec: Carlo Zaninetti , Jose' Rivera , Leonard Vater , Sandra Ohlenforst , Eva Leinøe , Doris Böckelmann , Kathleen Freson , Thomas Thiele , Houssain Makhloufi , Matthias Rath , Wolfgang Eberl , Martina Wolff , Carmen Freyer , Jan Wesche , Barbara Zieger , Ute Felbor , Florian H Heidel , Andreas Greinacher

Label-free on chip quality assessment of cellular blood products using real-time deformability cytometry.

Lab on a chip

Avec: Konstanze Aurich , Bob Fregin , Raghavendra Palankar , Jan Wesche , Oliver Hartwich , Doreen Biedenweg , Thi-Huong Nguyen , Andreas Greinacher , Oliver Otto

Polyvalent Immunoglobulin Preparations Inhibit Pneumolysin-Induced Platelet Destruction.

Thrombosis and haemostasis

Avec: Friederike Wiebe , Stefan Handtke , Jan Wesche , Annabel Schnarre , Raghavendra Palankar , Martina Wolff , Kristin Jahn , Franziska Voß , Sabrina Weißmüller , Jörg Schüttrumpf , Andreas Greinacher , Sven Hammerschmidt

JMJD6 Regulates Splicing of Its Own Gene Resulting in Alternatively Spliced Isoforms with Different Nuclear Targets.

International journal of molecular sciences

Avec: Nikoleta Raguz , Astrid Heim , Eden Engal , Juste Wesche , Juliane Merl-Pham , Stefanie M Hauck , Steffen Erkelenz , Heiner Schaal , Olivier Bensaude , Alexander Wolf , Maayan Salton , Angelika Böttger

Function of Large and Small Platelets Differs, Depending on Extracellular Calcium Availability and Type of Inductor.

Thrombosis and haemostasis

Avec: Stefan Handtke , Jan Wesche , Raghavendra Palankar , Andreas Greinacher , Thomas Thiele

Cytoskeleton Dependent Mobility Dynamics of FcγRIIA Facilitates Platelet Haptotaxis and Capture of Opsonized Bacteria.

Cells

Avec: Raghavendra Palankar , Laura Sachs , Jan Wesche , Andreas Greinacher

The platelet proteasome and immunoproteasome are stable in buffy-coat derived platelet concentrates for up to 7 days.

Transfusion

Avec: Lisa Colberg , Clemens Cammann , Jan Wesche , Eylin Topfstedt , Ulrike Seifert , Andreas Greinacher

Réseau de co-auteurs

Andreas Greinacher 25 collaborations

Raghavendra Palankar 13 collaborations

Stefan Handtke 9 collaborations

Thomas Thiele 8 collaborations

Martina Wolff 8 collaborations

Jørgen Wesche 7 collaborations

Sven Hammerschmidt 6 collaborations

Konstanze Aurich 6 collaborations

Kristin Jahn 5 collaborations

Theodore E Warkentin 4 collaborations

Linda Schönborn 4 collaborations

Michal Kostas 4 collaborations

Johanna Wesche 3 collaborations

Leif Steil 3 collaborations

Uwe Völker 3 collaborations

Thomas P Kohler 3 collaborations

Kathleen Selleng 3 collaborations

Oliver Otto 3 collaborations

Patrycja Szybowska 3 collaborations

Antoni Wiedlocha 3 collaborations

Ellen Margrethe Haugsten 3 collaborations

Sabrina Weißmüller 2 collaborations

Jörg Schüttrumpf 2 collaborations

Laura Sachs 2 collaborations

Carlo Zaninetti 2 collaborations

Thi-Huong Nguyen 2 collaborations

Christian Hentschker 2 collaborations

Stephan Michalik 2 collaborations

Alexander Reder 2 collaborations

Martin Beer 2 collaborations

Kati Franzke 2 collaborations

Florian Siegerist 2 collaborations

Nicole Endlich 2 collaborations

Ulrike Seifert 2 collaborations

Clemens Cammann 2 collaborations

Sachin Singh 2 collaborations

Sigve Nakken 2 collaborations

Chaoxi Luo 2 collaborations

Guido Schnabel 2 collaborations

Steven Obst 1 collaboration

Luke Heales 1 collaboration

Zachary Hrelja 1 collaboration

Prashneveet Ishri 1 collaboration

Lee Barber 1 collaboration

Jane Conrad 1 collaboration

Simran Cauhan 1 collaboration

Luise Kraus 1 collaboration

Myriam Ferrara 1 collaboration

Vishnu Dhople 1 collaboration

Geraldine Nouailles 1 collaboration

Manfred Rohde 1 collaboration

Corina Heinz 1 collaboration

Axel F Aschenbrenner 1 collaboration

Martin Witzenrath 1 collaboration

Julia Mayerle 1 collaboration

Sven Reiche 1 collaboration

Andrea Aebischer 1 collaboration

Maximilian Muenchhoff 1 collaboration

Johannes C Hellmuth 1 collaboration

Oliver T Keppler 1 collaboration

Daniel Duerschmied 1 collaboration

Achim Lother 1 collaboration

Siegbert Rieg 1 collaboration

Meinrad Paul Gawaz 1 collaboration

Karin Anne Lydia Mueller 1 collaboration

Christian S Scheer 1 collaboration

Matthias Napp 1 collaboration

Klaus Hahnenkamp 1 collaboration

Guglielmo Lucchese 1 collaboration

Antje Vogelgesang 1 collaboration

Agnes Flöel 1 collaboration

Piero Lovreglio 1 collaboration

Angela Stufano 1 collaboration

Rolf Marschalek 1 collaboration

None None 1 collaboration

Lea Lenkeit 1 collaboration

Markus Bender 1 collaboration

Olga Esteban 1 collaboration

Paulina Dobosz 1 collaboration

Marta Broto 1 collaboration

Sara Rovira Puig 1 collaboration

Jessica Fuhrmann 1 collaboration

Raquel Torres 1 collaboration

Josep Serra 1 collaboration

Roser Llevadot 1 collaboration

Marta Palicio 1 collaboration

Jing Jing Wang 1 collaboration

Tom Paul Gordon 1 collaboration

Edelgard Lindhoff-Last 1 collaboration

Till Hoffmann 1 collaboration

Lorenzo Alberio 1 collaboration

Florian Langer 1 collaboration

Christian Boehme 1 collaboration

Eugenia Biguzzi 1 collaboration

Leonie Grosse 1 collaboration

Matthias Endres 1 collaboration

Thomas G Liman 1 collaboration

Christian Kohler 1 collaboration

Yves Gruel 1 collaboration

Anne Sofie F Larsen 1 collaboration

Anne Therese Reiersen 1 collaboration

Inger Helene Nådland 1 collaboration

Jarlis Wesche 1 collaboration

Lena Ulm 1 collaboration

Nils-Olaf Hübner 1 collaboration

Karsten Becker 1 collaboration

Johannes Raster 1 collaboration

Kathrin Zimmermann 1 collaboration

Janina Bayer 1 collaboration

Christiane Wolz 1 collaboration

Martin Ulbricht 1 collaboration

Johanna Striesow 1 collaboration

Nicholas McKitterick 1 collaboration

Larissa M Busch 1 collaboration

Thomas von Woedtke 1 collaboration

Sander Bekeschus 1 collaboration

Kristian Wende 1 collaboration

Johannes-Moritz von Behren 1 collaboration

Kristin J Fritsch 1 collaboration

Laura Krüger 1 collaboration

Thomas Peter Kohler 1 collaboration

Arina Ozhiganova 1 collaboration

Ricarda Raschke 1 collaboration

Ulrike Strobel 1 collaboration

Van-Chien Bui 1 collaboration

Mihaela Delcea 1 collaboration

Michael Lalk 1 collaboration

Karen Methling 1 collaboration

Andreas Büttner 1 collaboration

Boris Fehse 1 collaboration

Evi X Stavrou 1 collaboration

Chandini Rangaswamy 1 collaboration

Reiner K Mailer 1 collaboration

Hanna Englert 1 collaboration

Maike Frye 1 collaboration

Stefan Kochanek 1 collaboration

Lea Krutzke 1 collaboration

Thomas Renné 1 collaboration

Aurora K Vikan 1 collaboration

Pål K Selbo 1 collaboration

Maximilian Schindler 1 collaboration

Manuela Gesell-Salazar 1 collaboration

Emil Reisinger 1 collaboration

Patience Shumba 1 collaboration

Phoenicia Quach 1 collaboration

Mathias Müsken 1 collaboration

Lakshmi Rajagopal 1 collaboration

Nikolai Siemens 1 collaboration

Vanessa Riechert 1 collaboration

Sascha Hein 1 collaboration

Mayken Visser 1 collaboration

Mathias Zimmermann 1 collaboration

Philipp A Adams 1 collaboration

Samuel A Theuerkauf 1 collaboration

Arezoo Jamali 1 collaboration

Andrea Wangorsch 1 collaboration

Andreas Reuter 1 collaboration

Alexander O Pasternak 1 collaboration

Jessica Hartmann 1 collaboration

Elena Herrera-Carrillo 1 collaboration

Ben Berkhout 1 collaboration

Klaus Cichutek 1 collaboration

Christian J Buchholz 1 collaboration

Elisa Fiorito 1 collaboration

Ellen M Haugsten 1 collaboration

Geir F Øy 1 collaboration

Gunhild M Mælandsmo 1 collaboration

Jonathan A Fletcher 1 collaboration

Leonardo A Meza-Zepeda 1 collaboration

Harleen Kaur 1 collaboration

Jhulia Gelain 1 collaboration

Cai Minzheng 1 collaboration

Dagim Shiferaw Tadele 1 collaboration

Joseph Robertson 1 collaboration

Richard Crispin 1 collaboration

Maria C Herrera 1 collaboration

Markéta Chlubnová 1 collaboration

Laure Piechaczyk 1 collaboration

Pilar Ayuda-Durán 1 collaboration

Sachin Kumar Singh 1 collaboration

Tobias Gedde-Dahl 1 collaboration

Yngvar Fløisand 1 collaboration

Jørn Skavland 1 collaboration

Bjørn-Tore Gjertsen 1 collaboration

Jorrit M Enserink 1 collaboration

Michael J Munson 1 collaboration

Benan J Mathai 1 collaboration

Matthew Yoke Wui Ng 1 collaboration

Laura Trachsel-Moncho 1 collaboration

Laura R de la Ballina 1 collaboration

Sebastian W Schultz 1 collaboration

Yahyah Aman 1 collaboration

Alf H Lystad 1 collaboration

Sakshi Singh 1 collaboration

Evandro F Fang 1 collaboration

Anne Simonsen 1 collaboration

Zhezheng Zeng 1 collaboration

Max Esefeld 1 collaboration

Khalil El Debuch 1 collaboration

Sabrina E Seck 1 collaboration

Lars Kaderali 1 collaboration

Sveinung Gundersen 1 collaboration

Fabian L M Bernal 1 collaboration

Dimitris Polychronopoulos 1 collaboration

Eivind Hovig 1 collaboration

Jose' Rivera 1 collaboration

Leonard Vater 1 collaboration

Sandra Ohlenforst 1 collaboration

Eva Leinøe 1 collaboration

Doris Böckelmann 1 collaboration

Kathleen Freson 1 collaboration

Houssain Makhloufi 1 collaboration

Matthias Rath 1 collaboration

Wolfgang Eberl 1 collaboration

Carmen Freyer 1 collaboration

Barbara Zieger 1 collaboration

Ute Felbor 1 collaboration

Florian H Heidel 1 collaboration

Bob Fregin 1 collaboration

Oliver Hartwich 1 collaboration

Doreen Biedenweg 1 collaboration

Friederike Wiebe 1 collaboration

Annabel Schnarre 1 collaboration

Franziska Voß 1 collaboration

Nikoleta Raguz 1 collaboration

Astrid Heim 1 collaboration

Eden Engal 1 collaboration

Juste Wesche 1 collaboration

Juliane Merl-Pham 1 collaboration

Stefanie M Hauck 1 collaboration

Steffen Erkelenz 1 collaboration

Heiner Schaal 1 collaboration

Olivier Bensaude 1 collaboration

Alexander Wolf 1 collaboration

Maayan Salton 1 collaboration

Angelika Böttger 1 collaboration

Lisa Colberg 1 collaboration

Eylin Topfstedt 1 collaboration