Maximilian Muenchhoff

Affiliations

Virology, Max von Pettenkofer Institute (M.M., O.K.), Ludwig-Maximilian University Munich, Germany.
German Center for Infection Research (DZIF), Partner Site Munich (M.M., O.K.).

Publications (66)

Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy.

Circulation

Avec: Leo Nicolai , Alexander Leunig , Sophia Brambs , Rainer Kaiser , Tobias Weinberger , Michael Weigand , Maximilian Muenchhoff , Johannes C Hellmuth , Stephan Ledderose , Heiko Schulz , Clemens Scherer , Martina Rudelius , Michael Zoller , Dominik Höchter , Oliver Keppler , Daniel Teupser , Bernhard Zwißler , Michael von Bergwelt-Baildon , Stefan Kääb , Steffen Massberg , Kami Pekayvaz , Konstantin Stark

Coincidental SARS-CoV-2 infection and mRNA vaccination: a case report addressing the most important clinical questions.

Infection

Avec: Ozan E Eren , Matthias Tonon , Florian Schöberl , Clemens Gießen-Jung , Andreas Moosmann , Alexandra Hollaus , Maximilian Muenchhoff , Konstantinos Dimitriadis

Early Initiation of Antiretroviral Therapy Following In Utero HIV Infection Is Associated With Low Viral Reservoirs but Other Factors Determine Viral Rebound.

The Journal of infectious diseases

Avec: Jane R Millar , Nomonde Bengu , Vinicius A Vieira , Emily Adland , Julia Roider , Maximilian Muenchhoff , Rowena Fillis , Kenneth Sprenger , Vuyokazi Ntlantsana , Isabella Fatti , Moherndran Archary , Andreas Groll , Nasreen Ismail , Maria C García-Guerrero , Philippa C Matthews , Thumbi Ndung'u , Maria C Puertas , Javier Martinez-Picado , Philip Goulder

Liver transplantation in a patient after COVID-19 - Rapid loss of antibodies and prolonged viral RNA shedding.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Avec: Hanno Niess , Nikolaus Börner , Maximilian Muenchhoff , Elham Khatamzas , Manfred Stangl , Alex Graf , Philipp Girl , Enrico Georgi , Dionysios Koliogiannis , Gerald Denk , Michael Irlbeck , Jens Werner , Markus Guba

Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells.

Cell reports. Medicine

Avec: Manuel Albanese , Hong-Ru Chen , Madeleine Gapp , Maximilian Muenchhoff , Hsiu-Hui Yang , David Peterhoff , Katja Hoffmann , Qianhao Xiao , Adrian Ruhle , Ina Ambiel , Stephanie Schneider , Ernesto Mejías-Pérez , Marcel Stern , Paul R Wratil , Katharina Hofmann , Laura Amann , Linda Jocham , Thimo Fuchs , Alessandro F Ulivi , Simon Besson-Girard , Simon Weidlich , Jochen Schneider , Christoph D Spinner , Kathrin Sutter , Ulf Dittmer , Andreas Humpe , Philipp Baumeister , Andreas Wieser , Simon Rothenfusser , Johannes Bogner , Julia Roider , Percy Knolle , Hartmut Hengel , Ralf Wagner , Vibor Laketa , Oliver T Fackler , Oliver T Keppler

How to exclude pulmonary embolism in patients hospitalized with COVID-19: a comparison of predictive scores.

Thrombosis journal

Avec: Jakob Vielhauer , Christopher Benesch , Anna Pernpruner , Anna-Lena Johlke , Johannes Christian Hellmuth , Maximilian Muenchhoff , Clemens Scherer , Nicola Fink , Bastian Sabel , Christian Schulz , Julia Mayerle , Ujjwal Mukund Mahajan , Hans Christian Stubbe

Omicron subvariants illustrate reduced respiratory tissue penetration, cell damage and inflammatory responses in human airway epithelia.

Frontiers in immunology

Avec: Viktoria Zaderer , Hussam Abd El Halim , Anna-Lena Wyremblewsky , Gaia Lupoli , Christopher Dächert , Maximilian Muenchhoff , Alexander Graf , Helmut Blum , Cornelia Lass-Flörl , Oliver T Keppler , Lukas A Huber , Wilfried Posch , Doris Wilflingseder

Viral genome sequencing to decipher in-hospital SARS-CoV-2 transmission events.

Scientific reports

Avec: Elisabeth Esser , Eva C Schulte , Alexander Graf , Alexander Karollus , Nicholas H Smith , Thomas Michler , Stefan Dvoretskii , Angel Angelov , Michael Sonnabend , Silke Peter , Christina Engesser , Aleksandar Radonic , Andrea Thürmer , Max von Kleist , Friedemann Gebhardt , Clarissa Prazeres da Costa , Dirk H Busch , Maximilian Muenchhoff , Helmut Blum , Oliver T Keppler , Julien Gagneur , Ulrike Protzer

Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection.

Nature communications

Avec: Emily Adland , Jane Millar , Nomonde Bengu , Maximilian Muenchhoff , Rowena Fillis , Kenneth Sprenger , Vuyokasi Ntlantsana , Julia Roider , Vinicius Vieira , Katya Govender , John Adamson , Nelisiwe Nxele , Christina Ochsenbauer , John Kappes , Luisa Mori , Jeroen van Lobenstein , Yeney Graza , Kogielambal Chinniah , Constant Kapongo , Roopesh Bhoola , Malini Krishna , Philippa C Matthews , Ruth Penya Poderos , Marta Colomer Lluch , Maria C Puertas , Julia G Prado , Neil McKerrow , Moherndran Archary , Thumbi Ndung'u , Andreas Groll , Pieter Jooste , Javier Martinez-Picado , Marcus Altfeld , Philip Goulder

Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Avec: Maximilian Muenchhoff , Helga Mairhofer , Hans Nitschko , Natascha Grzimek-Koschewa , Dieter Hoffmann , Annemarie Berger , Holger Rabenau , Marek Widera , Nikolaus Ackermann , Regina Konrad , Sabine Zange , Alexander Graf , Stefan Krebs , Helmut Blum , Andreas Sing , Bernhard Liebl , Roman Wölfel , Sandra Ciesek , Christian Drosten , Ulrike Protzer , Stephan Boehm , Oliver T Keppler

Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.

JCI insight

Avec: Rainer Kaiser , Alexander Leunig , Kami Pekayvaz , Oliver Popp , Markus Joppich , Vivien Polewka , Raphael Escaig , Afra Anjum , Marie-Louise Hoffknecht , Christoph Gold , Sophia Brambs , Anouk Engel , Sven Stockhausen , Viktoria Knottenberg , Anna Titova , Mohamed Haji , Clemens Scherer , Maximilian Muenchhoff , Johannes C Hellmuth , Kathrin Saar , Benjamin Schubert , Anne Hilgendorff , Christian Schulz , Stefan Kääb , Ralf Zimmer , Norbert Hübner , Steffen Massberg , Philipp Mertins , Leo Nicolai , Konstantin Stark

COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma.

HemaSphere

Avec: Erik Gaitzsch , Verena Passerini , Elham Khatamzas , Carolin D Strobl , Maximilian Muenchhoff , Clemens Scherer , Andreas Osterman , Michael Heide , Anna Reischer , Marion Subklewe , Alexandra Leutbecher , Benjamin Tast , Adrian Ruhle , Tobias Weiglein , Stephanie-Susanne Stecher , Hans J Stemmler , Martin Dreyling , Philipp Girl , Enrico Georgi , Roman Wölfel , Laura Mateyka , Elvira D'Ippolito , Kilian Schober , Dirk H Busch , Juliane Kager , Christoph D Spinner , Matthias Treiber , Sebastian Rasch , Tobias Lahmer , Roman Iakoubov , Jochen Schneider , Ulrike Protzer , Christof Winter , Jürgen Ruland , Michael Quante , Oliver T Keppler , Michael von Bergwelt-Baildon , Johannes Hellmuth , Oliver Weigert

Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection.

mSphere

Avec: M Muenchhoff , A W Chung , J Roider , Anne-Sophie Dugast , Simone Richardson , Henrik Kløverpris , Alasdair Leslie , Thumbi Ndung'u , Penny Moore , Galit Alter , Philip J R Goulder

Evaluation of two rapid antigen tests to detect SARS-CoV-2 in a hospital setting.

Medical microbiology and immunology

Avec: Andreas Osterman , Hanna-Mari Baldauf , Marwa Eletreby , Jochen M Wettengel , Suliman Q Afridi , Thimo Fuchs , Elena Holzmann , Anton Maier , Johanna Döring , Natascha Grzimek-Koschewa , Maximilian Muenchhoff , Ulrike Protzer , Lars Kaderali , Oliver T Keppler

Liver function test abnormalities at hospital admission are associated with severe course of SARS-CoV-2 infection: a prospective cohort study.

Gut

Avec: Sabine Weber , Johannes C Hellmuth , Clemens Scherer , Maximilian Muenchhoff , Julia Mayerle , Alexander L Gerbes

Impaired detection of omicron by SARS-CoV-2 rapid antigen tests.

Medical microbiology and immunology

Avec: Andreas Osterman , Irina Badell , Elif Basara , Marcel Stern , Fabian Kriesel , Marwa Eletreby , Gamze Naz Öztan , Melanie Huber , Hanna Autenrieth , Ricarda Knabe , Patricia M Späth , Maximilian Muenchhoff , Alexander Graf , Stefan Krebs , Helmut Blum , Jürgen Durner , Ludwig Czibere , Christopher Dächert , Lars Kaderali , Hanna-Mari Baldauf , Oliver T Keppler

Impaired function and delayed regeneration of dendritic cells in COVID-19.

PLoS pathogens

Avec: Elena Winheim , Linus Rinke , Konstantin Lutz , Anna Reischer , Alexandra Leutbecher , Lina Wolfram , Lisa Rausch , Jan Kranich , Paul R Wratil , Johanna E Huber , Dirk Baumjohann , Simon Rothenfusser , Benjamin Schubert , Anne Hilgendorff , Johannes C Hellmuth , Clemens Scherer , Maximilian Muenchhoff , Michael von Bergwelt-Baildon , Konstantin Stark , Tobias Straub , Thomas Brocker , Oliver T Keppler , Marion Subklewe , Anne B Krug

Ketone Bodies Improve Human CD8

Frontiers in medicine

Avec: Simon Hirschberger , Luca Gellert , David Effinger , Maximilian Muenchhoff , Markus Herrmann , Josef-Maria Briegel , Bernhard Zwißler , Simone Kreth

Ten rapid antigen tests for SARS-CoV-2 widely differ in their ability to detect Omicron-BA.4 and -BA.5.

Medical microbiology and immunology

Avec: Franziska Krenn , Christopher Dächert , Irina Badell , Gaia Lupoli , Gamze Naz Öztan , Tianle Feng , Nikolas Schneider , Melanie Huber , Hanna Both , Patricia M Späth , Maximilian Muenchhoff , Alexander Graf , Stefan Krebs , Helmut Blum , Jürgen Durner , Ludwig Czibere , Lars Kaderali , Oliver T Keppler , Hanna-Mari Baldauf , Andreas Osterman

Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP).

Infection

Avec: Fridolin Steinbeis , Charlotte Thibeault , Sarah Steinbrecher , Yvonne Ahlgrimm , Ira An Haack , Dietrich August , Beate Balzuweit , Carla Bellinghausen , Sarah Berger , Irina Chaplinskaya-Sobol , Oliver Cornely , Patrick Doeblin , Matthias Endres , Claudia Fink , Carsten Finke , Sandra Frank , Sabine Hanß , Tim Hartung , Johannes Christian Hellmuth , Susanne Herold , Peter Heuschmann , Jan Heyckendorf , Ralf Heyder , Stefan Hippenstiel , Wolfgang Hoffmann , Sebastian Ulrich Kelle , Philipp Knape , Philipp Koehler , Lucie Kretzler , David Manuel Leistner , Jasmin Lienau , Roberto Lorbeer , Bettina Lorenz-Depiereux , Constanze Dorothea Lüttke , Knut Mai , Uta Merle , Lil Antonia Meyer-Arndt , Olga Miljukov , Maximilian Muenchhoff , Moritz Müller-Plathe , Julia Neuhann , Hannelore Neuhauser , Alexandra Nieters , Christian Otte , Daniel Pape , Rafaela Maria Pinto , Christina Pley , Annett Pudszuhn , Philipp Reuken , Siegberg Rieg , Petra Ritter , Gernot Rohde , Maria Rönnefarth , Michael Ruzicka , Jens Schaller , Anne Schmidt , Sein Schmidt , Verena Schwachmeyer , Georg Schwanitz , Werner Seeger , Dana Stahl , Nicole Stobäus , Hans Christian Stubbe , Norbert Suttorp , Bettina Temmesfeld , Sylvia Thun , Paul Triller , Frederik Trinkmann , Istvan Vadasz , Heike Valentin , Maria Vehreschild , Christof von Kalle , Marie von Lilienfeld-Toal , Joachim Weber , Tobias Welte , Christian Wildberg , Robert Wizimirski , Saskia Zvork , Leif Erik Sander , Janne Vehreschild , Thomas Zoller , Florian Kurth , Martin Witzenrath

[Integration of Inventory Data from Cohort and Registry Studies into an Existing Research Network: National Pandemic Cohort Network (NAPKON)].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))

Avec: Anna-Lena Hofmann , Jörg Janne Vehreschild , Martin Witzenrath , Wolfgang Hoffmann , Thomas Illig , Stefan Schreiber , Gabriele Anton , Johannes Christian Hellmuth , Maximilian Muenchhoff , Clemens Scherer , Christina Pley , Charlotte Thibeault , Florian Kurth , Sarah Berger , Michael Hummel , Sina Marie Hopff , Melanie Stecher , Katharina Appel , Dana Stahl , Monika Kraus , Bettina Lorenz-Depiereux , Sabine Hanß , Sebastian von Kielmansegg , Irene Schlünder , Anna Niemeyer , Peter Heuschmann , Michael Krawczak , Jens-Peter Reese

Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection.

Nature communications

Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children.

Frontiers in immunology

Avec: Julia Roider , J Zachary Porterfield , Paul Ogongo , Maximilian Muenchhoff , Emily Adland , Andreas Groll , Lynn Morris , Penny L Moore , Thumbi Ndung'u , Henrik Kløverpris , Philip J R Goulder , Alasdair Leslie

Strong sex bias in elite control of paediatric HIV infection.

AIDS (London, England)

Avec: Vinicius A Vieira , Peter Zuidewind , Maximilian Muenchhoff , Julia Roider , Jane Millar , Margaret Clapson , Anriette Van Zyl , Delane Shingadia , Emily Adland , Rohin Athavale , Nicholas Grayson , M Azim Ansari , Christian Brander , Claudia Fortuny Guash , Lars Naver , Thanyawee Puthanakit , Wipaporn Natalie Songtaweesin , Jintanat Ananworanich , Denise Peluso , Beatriz Thomé , Jorge Pinto , Pieter Jooste , Gareth Tudor-Williams , Mark F Cotton , Philip Goulder

Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy.

Cell reports

Avec: Alveera Singh , Samuel W Kazer , Julia Roider , Kami C Krista , Jane Millar , Osaretin E Asowata , Abigail Ngoepe , Duran Ramsuran , Rabiah Fardoos , Amanda Ardain , Maximilian Muenchhoff , Warren Kuhn , Farina Karim , Thumbi Ndung'u , Alex K Shalek , Philip Goulder , Alasdair Leslie , Henrik N Kløverpris

Genomic epidemiology reveals multiple introductions of SARS-CoV-2 followed by community and nosocomial spread, Germany, February to May 2020.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Avec: Maximilian Muenchhoff , Alexander Graf , Stefan Krebs , Caroline Quartucci , Sandra Hasmann , Johannes C Hellmuth , Clemens Scherer , Andreas Osterman , Stephan Boehm , Christopher Mandel , Andrea Sabine Becker-Pennrich , Michael Zoller , Hans Christian Stubbe , Stefan Munker , Dieter Munker , Katrin Milger , Madeleine Gapp , Stephanie Schneider , Adrian Ruhle , Linda Jocham , Leo Nicolai , Kami Pekayvaz , Tobias Weinberger , Helga Mairhofer , Elham Khatamzas , Katharina Hofmann , Patricia M Spaeth , Sabine Bender , Stefan Kääb , Bernhard Zwissler , Julia Mayerle , Juergen Behr , Michael von Bergwelt-Baildon , Martin Reincke , Beatrice Grabein , Christian Ludwig Hinske , Helmut Blum , Oliver T Keppler

Spatially resolved qualified sewage spot sampling to track SARS-CoV-2 dynamics in Munich - One year of experience.

The Science of the total environment

Avec: Raquel Rubio-Acero , Jessica Beyerl , Maximilian Muenchhoff , Marc Sancho Roth , Noemi Castelletti , Ivana Paunovic , Katja Radon , Bernd Springer , Christian Nagel , Bernhard Boehm , Merle M Böhmer , Alexander Graf , Helmut Blum , Stefan Krebs , Oliver T Keppler , Andreas Osterman , Zohaib Nisar Khan , Michael Hoelscher , Andreas Wieser , Auteur inconnu

Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein.

Blood

Avec: Andreas Greinacher , Kathleen Selleng , Julia Mayerle , Raghavendra Palankar , Jan Wesche , Sven Reiche , Andrea Aebischer , Theodore E Warkentin , Maximilian Muenchhoff , Johannes C Hellmuth , Oliver T Keppler , Daniel Duerschmied , Achim Lother , Siegbert Rieg , Meinrad Paul Gawaz , Karin Anne Lydia Mueller , Christian S Scheer , Matthias Napp , Klaus Hahnenkamp , Guglielmo Lucchese , Antje Vogelgesang , Agnes Flöel , Piero Lovreglio , Angela Stufano , Rolf Marschalek , Thomas Thiele , Auteur inconnu

Detection of SARS-CoV-2-RNA in post-mortem samples of human eyes.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Avec: Josef Penkava , Maximilian Muenchhoff , Irina Badell , Andreas Osterman , Claire Delbridge , Florian Niederbuchner , Sarah Soliman , Martina Rudelius , Alexander Graf , Stefan Krebs , Helmut Blum , Michael Ulbig , Carmen Baumann , Daniel Zapp , Mathias Maier , Oliver T Keppler , Chris P Lohmann , Stephan Ledderose

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.

Nature communications

Avec: Kami Pekayvaz , Alexander Leunig , Rainer Kaiser , Markus Joppich , Sophia Brambs , Aleksandar Janjic , Oliver Popp , Daniel Nixdorf , Valeria Fumagalli , Nora Schmidt , Vivien Polewka , Afra Anjum , Viktoria Knottenberg , Luke Eivers , Lucas E Wange , Christoph Gold , Marieluise Kirchner , Maximilian Muenchhoff , Johannes C Hellmuth , Clemens Scherer , Raquel Rubio-Acero , Tabea Eser , Flora Deák , Kerstin Puchinger , Niklas Kuhl , Andreas Linder , Kathrin Saar , Lukas Tomas , Christian Schulz , Andreas Wieser , Wolfgang Enard , Inge Kroidl , Christof Geldmacher , Michael von Bergwelt-Baildon , Oliver T Keppler , Mathias Munschauer , Matteo Iannacone , Ralf Zimmer , Philipp Mertins , Norbert Hubner , Michael Hoelscher , Steffen Massberg , Konstantin Stark , Leo Nicolai

Distinct and dynamic activation profiles of circulating dendritic cells and monocytes in mild COVID-19 and after yellow fever vaccination.

European journal of immunology

Avec: Elena Winheim , Tabea Eser , Flora Deák , Mohamed I M Ahmed , Olga Baranov , Linus Rinke , Katharina Eisenächer , Antonio Santos-Peral , Hadi Karimzadeh , Michael Pritsch , Clemens Scherer , Maximilian Muenchhoff , Johannes C Hellmuth , Michael von Bergwelt-Baildon , Laura Olbrich , Michael Hoelscher , Andreas Wieser , Inge Kroidl , Simon Rothenfusser , Christof Geldmacher , Anne B Krug

Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Alina Bauer , Elisabeth Pachl , Johannes C Hellmuth , Nikolaus Kneidinger , Motaharehsadat Heydarian , Marion Frankenberger , Hans C Stubbe , Bernhard Ryffel , Agnese Petrera , Stefanie M Hauck , Jürgen Behr , Rainer Kaiser , Clemens Scherer , Li Deng , Daniel Teupser , Narges Ahmidi , Maximilian Muenchhoff , Benjamin Schubert , Anne Hilgendorff

Antiviral drugs block replication of highly immune-evasive Omicron subvariants ex vivo, but fail to reduce tissue inflammation.

Antiviral research

Avec: Stefanie Dichtl , Gabriel Diem , Michael Jäger , Viktoria Zaderer , Gaia Lupoli , Christopher Dächert , Maximilian Muenchhoff , Alexander Graf , Helmut Blum , Oliver T Keppler , Cornelia Lass-Flörl , Günter Weiss , Doris Wilflingseder , Wilfried Posch

Salivary antibodies induced by BA.4/BA.5-convalescence or bivalent booster Immunoglobulin vaccination protect against novel SARS-COV-2 variants of concern.

Microbiology spectrum

Avec: Gabriel Diem , Stefanie Dichtl , Viktoria Zaderer , Cornelia Lass-Flörl , Markus Reindl , Gaia Lupoli , Christopher Dächert , Maximilian Muenchhoff , Alexander Graf , Helmut Blum , Oliver T Keppler , Doris Wilflingseder , Wilfried Posch

Long-term monitoring of SARS-CoV-2 seroprevalence and variants in Ethiopia provides prediction for immunity and cross-immunity.

Nature communications

Avec: Simon Merkt , Solomon Ali , Esayas Kebede Gudina , Wondimagegn Adissu , Addisu Gize , Maximilian Muenchhoff , Alexander Graf , Stefan Krebs , Kira Elsbernd , Rebecca Kisch , Sisay Sirgu Betizazu , Bereket Fantahun , Delayehu Bekele , Raquel Rubio-Acero , Mulatu Gashaw , Eyob Girma , Daniel Yilma , Ahmed Zeynudin , Ivana Paunovic , Michael Hoelscher , Helmut Blum , Jan Hasenauer , Arne Kroidl , Andreas Wieser

Severe underquantification of HIV-1 group O isolates by major commercial PCR-based assays.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Avec: A Berger , M Muenchhoff , K Hourfar , M Kortenbusch , I Ambiel , L Stegmann , A Heim , C Sarrazin , R Ehret , V Daniel , M Wasner , J-C Plantier , J Eberle , L Gürtler , A E Haberl , M Stürmer , O T Keppler

Binding of phosphatidylserine-positive microparticles by PBMCs classifies disease severity in COVID-19 patients.

Journal of extracellular vesicles

Avec: Lisa Rausch , Konstantin Lutz , Martina Schifferer , Elena Winheim , Rudi Gruber , Elina F Oesterhaus , Linus Rinke , Johannes C Hellmuth , Clemens Scherer , Maximilian Muenchhoff , Christopher Mandel , Michael Bergwelt-Baildon , Mikael Simons , Tobias Straub , Anne B Krug , Jan Kranich , Thomas Brocker

An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults.

PLoS pathogens

Avec: Vinicius A Vieira , Emily Adland , David F G Malone , Maureen P Martin , Andreas Groll , M Azim Ansari , Maria C Garcia-Guerrero , Mari C Puertas , Maximilian Muenchhoff , Claudia Fortuny Guash , Christian Brander , Javier Martinez-Picado , Alasdair Bamford , Gareth Tudor-Williams , Thumbi Ndung'u , Bruce D Walker , Veron Ramsuran , John Frater , Pieter Jooste , Dimitra Peppa , Mary Carrington , Philip J R Goulder

Dynamics of SARS-CoV-2 shedding in the respiratory tract depends on the severity of disease in COVID-19 patients.

The European respiratory journal

Avec: Dieter Munker , Andreas Osterman , Hans Stubbe , Maximilian Muenchhoff , Tobias Veit , Tobias Weinberger , Michaela Barnikel , Jan-Niclas Mumm , Katrin Milger , Elham Khatamzas , Sarah Klauss , Clemens Scherer , Johannes C Hellmuth , Clemens Giessen-Jung , Michael Zoller , Tobias Herold , Stephanie Stecher , Enrico N de Toni , Christian Schulz , Nikolaus Kneidinger , Oliver T Keppler , Jürgen Behr , Julia Mayerle , Stefan Munker

Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia.

Journal of thrombosis and haemostasis : JTH

Avec: Leo Nicolai , Alexander Leunig , Sophia Brambs , Rainer Kaiser , Markus Joppich , Marie-Louise Hoffknecht , Christoph Gold , Anouk Engel , Vivien Polewka , Maximilian Muenchhoff , Johannes C Hellmuth , Adrian Ruhle , Stephan Ledderose , Tobias Weinberger , Heiko Schulz , Clemens Scherer , Martina Rudelius , Michael Zoller , Oliver T Keppler , Bernhard Zwißler , Michael von Bergwelt-Baildon , Stefan Kääb , Ralf Zimmer , Roman D Bülow , Saskia von Stillfried , Peter Boor , Steffen Massberg , Kami Pekayvaz , Konstantin Stark

Should routine risk reduction procedures for the prevention and control of pandemics become a standard in all oncological outpatient clinics? The prospective COVID-19 cohort study: protect-CoV.

Medical oncology (Northwood, London, England)

Avec: Theres Fey , Nicole Erickson , Arndt Stahler , Maximilian Muenchhoff , Oliver T Keppler , Katharina Ruehlmann , Gabriele Krauss-Pfeiffer , Hannah Steinberg , Alexander Graf , Stefan Krebs , Helmut Blum , Elham Khatamzas , Sarah Seynstahl , Jozefina Casuscelli , Daniel Markwardt , Roswitha Forstpointner , Timo Schinköthe , Michael von Bergwelt-Baildon , Volker Heinemann

Rapid and sensitive identification of omicron by variant-specific PCR and nanopore sequencing: paradigm for diagnostics of emerging SARS-CoV-2 variants.

Medical microbiology and immunology

Avec: Christopher Dächert , Maximilian Muenchhoff , Alexander Graf , Hanna Autenrieth , Sabine Bender , Helga Mairhofer , Paul R Wratil , Susanne Thieme , Stefan Krebs , Natascha Grzimek-Koschewa , Helmut Blum , Oliver T Keppler

Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.

Nature medicine

Avec: Paul R Wratil , Marcel Stern , Alina Priller , Annika Willmann , Giovanni Almanzar , Emanuel Vogel , Martin Feuerherd , Cho-Chin Cheng , Sarah Yazici , Catharina Christa , Samuel Jeske , Gaia Lupoli , Tim Vogt , Manuel Albanese , Ernesto Mejías-Pérez , Stefan Bauernfried , Natalia Graf , Hrvoje Mijocevic , Martin Vu , Kathrin Tinnefeld , Jochen Wettengel , Dieter Hoffmann , Maximilian Muenchhoff , Christopher Daechert , Helga Mairhofer , Stefan Krebs , Volker Fingerle , Alexander Graf , Philipp Steininger , Helmut Blum , Veit Hornung , Bernhard Liebl , Klaus Überla , Martina Prelog , Percy Knolle , Oliver T Keppler , Ulrike Protzer

Ethical and coordinative challenges in setting up a national cohort study during the COVID-19 pandemic in Germany.

BMC medical ethics

Avec: Katharina Tilch , Sina M Hopff , Katharina Appel , Monika Kraus , Bettina Lorenz-Depiereux , Lisa Pilgram , Gabi Anton , Sarah Berger , Ramsia Geisler , Kirsten Haas , Thomas Illig , Dagmar Krefting , Roberto Lorbeer , Lazar Mitrov , Maximilian Muenchhoff , Matthias Nauck , Christina Pley , Jens-Peter Reese , Siegbert Rieg , Margarete Scherer , Melanie Stecher , Christoph Stellbrink , Heike Valentin , Christof Winter , Martin Witzenrath , J Janne Vehreschild

Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation.

Infection

Avec: Olaf M Glueck , Xiaoling Liang , Irina Badell , Paul R Wratil , Alexander Graf , Stefan Krebs , Helmut Blum , Johannes C Hellmuth , Clemens Scherer , Alexandra Hollaus , Patricia M Spaeth , Burak Karakoc , Thimo Fuchs , Julia Zimmermann , Teresa Kauke , Andreas Moosmann , Oliver T Keppler , Christian Schneider , Maximilian Muenchhoff

Variable detection of Omicron-BA.1 and -BA.2 by SARS-CoV-2 rapid antigen tests.

Medical microbiology and immunology

Avec: Andreas Osterman , Irina Badell , Christopher Dächert , Nikolas Schneider , Anna-Yasemin Kaufmann , Gamze Naz Öztan , Melanie Huber , Patricia M Späth , Marcel Stern , Hanna Autenrieth , Maximilian Muenchhoff , Alexander Graf , Stefan Krebs , Helmut Blum , Ludwig Czibere , Jürgen Durner , Lars Kaderali , Hanna-Mari Baldauf , Oliver T Keppler

Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.

Nature cancer

Avec: Andrea Keppler-Hafkemeyer , Christine Greil , Paul R Wratil , Khalid Shoumariyeh , Marcel Stern , Annika Hafkemeyer , Driti Ashok , Alexandra Hollaus , Gaia Lupoli , Alina Priller , Marie L Bischof , Gabriele Ihorst , Monika Engelhardt , Reinhard Marks , Jürgen Finke , Hannah Bertrand , Christopher Dächert , Maximilian Muenchhoff , Irina Badell , Florian Emmerich , Hridi Halder , Patricia M Spaeth , Percy A Knolle , Ulrike Protzer , Michael von Bergwelt-Baildon , Justus Duyster , Tanja N Hartmann , Andreas Moosmann , Oliver T Keppler

Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages.

Medical microbiology and immunology

Avec: Andreas Osterman , Franziska Krenn , Maximilian Iglhaut , Irina Badell , Andreas Lehner , Patricia M Späth , Marcel Stern , Hanna Both , Sabine Bender , Maximilian Muenchhoff , Alexander Graf , Stefan Krebs , Helmut Blum , Timo Grimmer , Jürgen Durner , Ludwig Czibere , Christopher Dächert , Natascha Grzimek-Koschewa , Ulrike Protzer , Lars Kaderali , Hanna-Mari Baldauf , Oliver T Keppler

Preserved prenatal lung growth assessed by fetal MRI in the omicron-dominated phase of the SARS-CoV-2 pandemic.

European radiology

Avec: Gloria Biechele , Vanessa Koliogiannis , Philippe Rennollet , Tobias Prester , Enrico Schulz , Thomas Kolben , Magdalena Jegen , Christoph Hübener , Uwe Hasbargen , Andreas Flemmer , Olaf Dietrich , Tanja Burkard , Regina Schinner , Julien Dinkel , Maximilian Muenchhoff , Susan Hintz , Maria Delius , Sven Mahner , Jens Ricke , Anne Hilgendorff , Sophia Stoecklein

Prospective Longitudinal Serosurvey of Healthcare Workers in the First Wave of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pandemic in a Quaternary Care Hospital in Munich, Germany.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Tobias Weinberger , Julius Steffen , Andreas Osterman , Tonina T Mueller , Maximilian Muenchhoff , Paul R Wratil , Alexander Graf , Stefan Krebs , Caroline Quartucci , Patricia M Spaeth , Beatrice Grabein , Kristina Adorjan , Helmut Blum , Oliver T Keppler , Matthias Klein

Myocardial Inflammation and Dysfunction in COVID-19-Associated Myocardial Injury.

Circulation. Cardiovascular imaging

Avec: Ludwig T Weckbach , Adrian Curta , Stephanie Bieber , Angelina Kraechan , Johannes Brado , Johannes C Hellmuth , Maximilian Muenchhoff , Clemens Scherer , Ines Schroeder , Michael Irlbeck , Stefan Maurus , Jens Ricke , Karin Klingel , Stefan Kääb , Mathias Orban , Steffen Massberg , Jörg Hausleiter , Ulrich Grabmaier

Left and right ventricular dysfunction in patients with COVID-19-associated myocardial injury.

Infection

Avec: Stéphanie Bieber , Angelina Kraechan , Johannes C Hellmuth , Maximilian Muenchhoff , Clemens Scherer , Ines Schroeder , Michael Irlbeck , Stefan Kaeaeb , Steffen Massberg , Joerg Hausleiter , Ulrich Grabmaier , Mathias Orban , Ludwig T Weckbach

Increased Regulatory T-Cell Activity and Enhanced T-Cell Homeostatic Signaling in Slow Progressing HIV-infected Children.

Frontiers in immunology

Avec: Julia Roider , Abigail Ngoepe , Maximilian Muenchhoff , Emily Adland , Andreas Groll , Thumbi Ndung'u , Henrik Kløverpris , Philip Goulder , Alasdair Leslie

Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children.

The Journal of infectious diseases

Avec: Maximilian Muenchhoff , Emily Adland , Julia Roider , Henrik Kløverpris , Alasdair Leslie , Stephan Boehm , Oliver T Keppler , Thumbi Ndung'u , Philip J R Goulder

Clinical and Epidemiological Features of a Family Cluster of Symptomatic and Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

Journal of the Pediatric Infectious Diseases Society

Avec: Gerhard K Wolf , Thomas Glueck , Johannes Huebner , Maximilian Muenchhoff , Dieter Hoffmann , Lars E French , Oliver T Keppler , Ulrike Protzer

HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE.

EClinicalMedicine

Avec: Jane R Millar , Nomonde Bengu , Rowena Fillis , Ken Sprenger , Vuyokazi Ntlantsana , Vinicius A Vieira , Nisreen Khambati , Moherndran Archary , Maximilian Muenchhoff , Andreas Groll , Nicholas Grayson , John Adamson , Katya Govender , Krista Dong , Photini Kiepiela , Bruce D Walker , David Bonsall , Thomas Connor , Matthew J Bull , Nelisiwe Nxele , Julia Roider , Nasreen Ismail , Emily Adland , Maria C Puertas , Javier Martinez-Picado , Philippa C Matthews , Thumbi Ndung'u , Philip Goulder , Auteur inconnu

Comparison of four commercial, automated antigen tests to detect SARS-CoV-2 variants of concern.

Medical microbiology and immunology

Avec: Andreas Osterman , Maximilian Iglhaut , Andreas Lehner , Patricia Späth , Marcel Stern , Hanna Autenrieth , Maximilian Muenchhoff , Alexander Graf , Stefan Krebs , Helmut Blum , Armin Baiker , Natascha Grzimek-Koschewa , Ulrike Protzer , Lars Kaderali , Hanna-Mari Baldauf , Oliver T Keppler

Robust HIV-specific CD4+ and CD8+ T-cell responses distinguish elite control in adolescents living with HIV from viremic nonprogressors.

AIDS (London, England)

Avec: Vinicius A Vieira , Jane Millar , Emily Adland , Maximilian Muenchhoff , Julia Roider , Claudia Fortuny Guash , Denise Peluso , Beatriz Thomé , Maria C Garcia-Guerrero , Mari C Puertas , Alasdair Bamford , Christian Brander , Mary Carrington , Javier Martinez-Picado , John Frater , Gareth Tudor-Williams , Philip Goulder

Case Report: Unilateral Sixth Cranial Nerve Palsy Associated With COVID-19 in a 2-year-old Child.

Frontiers in pediatrics

Avec: Katrin Knoflach , Eva Holzapfel , Timo Roser , Lieselotte Rudolph , Marco Paolini , Maximilian Muenchhoff , Andreas Osterman , Matthias Griese , Matthias Kappler , Ulrich von Both

Two Distinct Mechanisms Leading to Loss of Virological Control in the Rare Group of Antiretroviral Therapy-Naive, Transiently Aviremic Children Living with HIV.

Journal of virology

Avec: Vinicius A Vieira , Emily Adland , Nicholas E Grayson , Anna Csala , Fa'eeda Richards , Cherrelle Dacon , Rohin Athavale , Ming-Han Tsai , Reena D'Souza , Maximilian Muenchhoff , David Bonsall , Pieter Jooste , Philip J R Goulder

Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses.

Cell reports

Avec: Paul R Wratil , Niklas A Schmacke , Burak Karakoc , Alex Dulovic , Daniel Junker , Matthias Becker , Ulrich Rothbauer , Andreas Osterman , Patricia M Spaeth , Adrian Ruhle , Madeleine Gapp , Stephanie Schneider , Maximilian Muenchhoff , Johannes C Hellmuth , Clemens Scherer , Julia Mayerle , Martin Reincke , Juergen Behr , Stefan Kääb , Bernhard Zwissler , Michael von Bergwelt-Baildon , Josef Eberle , Lars Kaderali , Nicole Schneiderhan-Marra , Veit Hornung , Oliver T Keppler

CD74 is a functional MIF receptor on activated CD4

Cellular and molecular life sciences : CMLS

Avec: Lin Zhang , Iris Woltering , Mathias Holzner , Markus Brandhofer , Carl-Christian Schaefer , Genta Bushati , Simon Ebert , Bishan Yang , Maximilian Muenchhoff , Johannes C Hellmuth , Clemens Scherer , Christian Wichmann , David Effinger , Max Hübner , Omar El Bounkari , Patrick Scheiermann , Jürgen Bernhagen , Adrian Hoffmann

Secondary zoonotic dog-to-human transmission of SARS-CoV-2 suggested by timeline but refuted by viral genome sequencing.

Infection

Avec: John M Hoppe , Louise U Füeßl , Katrin Hartmann , Regina Hofmann-Lehmann , Alexander Graf , Stefan Krebs , Helmut Blum , Irina Badell , Oliver T Keppler , Maximilian Muenchhoff

Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection.

Nature communications

Avec: Elham Khatamzas , Markus H Antwerpen , Alexandra Rehn , Alexander Graf , Johannes Christian Hellmuth , Alexandra Hollaus , Anne-Wiebe Mohr , Erik Gaitzsch , Tobias Weiglein , Enrico Georgi , Clemens Scherer , Stephanie-Susanne Stecher , Stefanie Gruetzner , Helmut Blum , Stefan Krebs , Anna Reischer , Alexandra Leutbecher , Marion Subklewe , Andrea Dick , Sabine Zange , Philipp Girl , Katharina Müller , Oliver Weigert , Karl-Peter Hopfner , Hans-Joachim Stemmler , Michael von Bergwelt-Baildon , Oliver T Keppler , Roman Wölfel , Maximilian Muenchhoff , Andreas Moosmann

Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype.

JCI insight

Avec: Vinicius Vieira , Nicholas Lim , Alveera Singh , Ellen Leitman , Reena Dsouza , Emily Adland , Maximilian Muenchhoff , Julia Roider , Miguel Marin Lopez , Julieta Carabelli , Jennifer Giandhari , Andreas Groll , Pieter Jooste , Julia G Prado , Christina Thobakgale , Krista Dong , Photini Kiepiela , Andrew J Prendergast , Gareth Tudor-Williams , John Frater , Bruce D Walker , Thumbi Ndung'u , Veron Ramsuran , Alasdair Leslie , Henrik N Kløverpris , Philip Goulder

Magnitude of Type I Interferon Responses by Plasmacytoid Dendritic Cells After TLR7 Stimulation Is Associated With Human Immunodeficiency Virus Type 1 (HIV-1) Reservoir Sizes in Cisgender Women With HIV-1 on Antiretroviral Therapy.

The Journal of infectious diseases

Avec: Rebecca-Jo Thiele , Benjamin Grünhagel , Maximilian Muenchhoff , Maria Pujantell-Graell , Linda Jocham , Arne Düsedau , Jana Hennesen , Heike Hildebrandt , Sven Hendrik Hagen , Deborah Sandfort , Madeleine J Bunders , Oliver T Keppler , Christian Hoffmann , Marcus Altfeld

Réseau de co-auteurs

Oliver T Keppler 33 collaborations

Alexander Graf 21 collaborations

Helmut Blum 21 collaborations

Clemens Scherer 20 collaborations

Johannes C Hellmuth 17 collaborations

Stefan Krebs 17 collaborations

Andreas Osterman 14 collaborations

Emily Adland 12 collaborations

Julia Roider 12 collaborations

Michael von Bergwelt-Baildon 11 collaborations

Thumbi Ndung'u 11 collaborations

Philip Goulder 9 collaborations

Christopher Dächert 9 collaborations

Ulrike Protzer 9 collaborations

Andreas Groll 8 collaborations

Paul R Wratil 8 collaborations

Irina Badell 8 collaborations

Marcel Stern 7 collaborations

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Vinicius A Vieira 6 collaborations

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Nomonde Bengu 4 collaborations

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Christian Schulz 4 collaborations

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None None 3 collaborations

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