Hartmut Hengel

Affiliations
  • Institute of Virology, University Medical Center, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany; and.
  • Faculty of Medicine, Albert-Ludwigs-University Freiburg, 79104 Freiburg, Germany.
ORCID: 0000-0002-3482-816X

Publications (60)

KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals.

Journal of immunology (Baltimore, Md. : 1950)
Avec: Angela R Manser , Nadine Scherenschlich , Christine Thöns , Hartmut Hengel , Jörg Timm , Markus Uhrberg

Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy.

Genetics in medicine : official journal of the American College of Medical Genetics
Avec: René G Feichtinger , Bettina E Mucha , Holger Hengel , Zakaria Orfi , Christine Makowski , Junio Dort , Guy D'Anjou , Thi Tuyet Mai Nguyen , Rebecca Buchert , Hendrik Juenger , Peter Freisinger , Sarah Baumeister , Benedikt Schoser , Uwe Ahting , Reinhard Keimer , Cam-Tu Emilie Nguyen , Paul Fabre , Julie Gauthier , Marguerite Miguet , Fátima Lopes , Afnan AlHakeem , Amal AlHashem , Brahim Tabarki , Krishna Kumar Kandaswamy , Peter Bauer , Peter Steinbacher , Holger Prokisch , Marc Sturm , Tim M Strom , Benjamin Ellezam , Johannes A Mayr , Ludger Schöls , Jacques L Michaud , Philippe M Campeau , Tobias B Haack , Nicolas A Dumont

Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood.

Movement disorders : official journal of the Movement Disorder Society
Avec: Jeannette Hübener-Schmid , Kirsten Kuhlbrodt , Julien Peladan , Jennifer Faber , Magda M Santana , Holger Hengel , Heike Jacobi , Kathrin Reetz , Hector Garcia-Moreno , Mafalda Raposo , Judith van Gaalen , Jon Infante , Katharina M Steiner , Jeroen de Vries , Marcel M Verbeek , Paola Giunti , Luis Pereira de Almeida , Manuela Lima , Bart van de Warrenburg , Ludger Schöls , Thomas Klockgether , Matthis Synofzik , Auteur inconnu , Olaf Riess

Safety and Efficacy of Acetyl-DL-Leucine in Certain Types of Cerebellar Ataxia: The ALCAT Randomized Clinical Crossover Trial.

JAMA network open
Avec: Katharina Feil , Christine Adrion , Sylvia Boesch , Sarah Doss , Ilaria Giordano , Holger Hengel , Heike Jacobi , Thomas Klockgether , Thomas Klopstock , Wolfgang Nachbauer , Ludger Schöls , Katharina Marie Steiner , Claudia Stendel , Dagmar Timmann , Ivonne Naumann , Ulrich Mansmann , Michael Strupp , Auteur inconnu

Characterization of cognitive impairment in adult polyglucosan body disease.

Journal of neurology
Avec: Paul Theo Zebhauser , Isabell Cordts , Holger Hengel , Bernhard Haslinger , Paul Lingor , Hasan Orhan Akman , Tobias B Haack , Marcus Deschauer

Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis.

Journal of lipid research
Avec: Philip Höflinger , Stefan Hauser , Eylan Yutuc , Holger Hengel , Lauren Griffiths , Florentine Radelfahr , Owain W Howell , Yuqin Wang , Sonja L Connor , P Barton Duell , Andrea E DeBarber , Peter Martus , Dieter Lütjohann , William J Griffiths , Ludger Schöls

Levels of Neurofilament Light at the Preataxic and Ataxic Stages of Spinocerebellar Ataxia Type 1.

Neurology
Avec: Carlo Wilke , David Mengel , Ludger Schöls , Holger Hengel , Maria Rakowicz , Thomas Klockgether , Alexandra Durr , Alessandro Filla , Bela Melegh , Rebecca Schüle , Kathrin Reetz , Heike Jacobi , Matthis Synofzik

The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors.

Journal of neurology
Avec: Holger Hengel , Peter Martus , Jennifer Faber , Paola Giunit , Hector Garcia-Moreno , Nita Solanky , Thomas Klockgether , Kathrin Reetz , Bart P van de Warrenburg , Magda M Santana , Patrick Silva , Inês Cunha , Luís Pereira de Almeida , Dagmar Timmann , Jon Infante , Jeroen de Vries , Manuela Lima , Paula Pires , Khalaf Bushara , Heike Jacobi , Chiadi Onyike , Jeremy D Schmahmann , Jeannette Hübener-Schmid , Matthis Synofzik , Auteur inconnu , Ludger Schöls

Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus.

NPJ vaccines
Avec: Vu Thuy Khanh Le-Trilling , Andreja Jagnjić , Ilija Brizić , Mareike Eilbrecht , Kerstin Wohlgemuth , Carmen Rožmanić , Alan Herdman , Katja Hoffmann , Astrid M Westendorf , Hartmut Hengel , Stipan Jonjić , Mirko Trilling

Inhibition of B cell receptor signaling induced by the human adenovirus species D E3/49K protein.

Frontiers in immunology
Avec: Andreas Hildenbrand , Precious Cramer , Milena Bertolotti , Nathalie Sophia Kaiser , Kathrin Kläsener , Clara Muriel Nickel , Michael Reth , Albert Heim , Hartmut Hengel , Hans-Gerhard Burgert , Zsolt Ruzsics

Ad hoc laboratory-based surveillance of SARS-CoV-2 by real-time RT-PCR using minipools of RNA prepared from routine respiratory samples.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Avec: Anna M Eis-Hübinger , Mario Hönemann , Jürgen J Wenzel , Annemarie Berger , Marek Widera , Barbara Schmidt , Souhaib Aldabbagh , Benjamin Marx , Hendrik Streeck , Sandra Ciesek , Uwe G Liebert , Daniela Huzly , Hartmut Hengel , Marcus Panning

First-line exome sequencing in Palestinian and Israeli Arabs with neurological disorders is efficient and facilitates disease gene discovery.

European journal of human genetics : EJHG
Avec: Holger Hengel , Rebecca Buchert , Marc Sturm , Tobias B Haack , Yvonne Schelling , Muhammad Mahajnah , Rajech Sharkia , Abdussalam Azem , Ghassan Balousha , Zaid Ghanem , Mohammed Falana , Osama Balousha , Suhail Ayesh , Reinhard Keimer , Werner Deigendesch , Jimmy Zaidan , Hiyam Marzouqa , Peter Bauer , Ludger Schöls

Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection.

Frontiers in immunology
Avec: Dorien De Vlieger , Katja Hoffmann , Inge Van Molle , Wim Nerinckx , Lien Van Hoecke , Marlies Ballegeer , Sarah Creytens , Han Remaut , Hartmut Hengel , Bert Schepens , Xavier Saelens

HCMV Infection in a Mesenchymal Stem Cell Niche: Differential Impact on the Development of NK Cells versus ILC3.

Journal of clinical medicine
Avec: Ricarda Ising , Sandra Weinhold , Sabrina Bianca Bennstein , Albert Zimmermann , Özer Degistirici , Gesine Kögler , Roland Meisel , Hartmut Hengel , Jörg Timm , Markus Uhrberg

NK-cell responses are biased towards CD16-mediated effector functions in chronic hepatitis B virus infection.

Journal of hepatology
Avec: Anita Schuch , Britta Franziska Zecher , Philipp Andreas Müller , Margareta P Correia , Franziska Daul , Charlotte Rennert , Catrin Tauber , Karolin Schlitt , Tobias Boettler , Christoph Neumann-Haefelin , Hartmut Hengel , Hanspeter Pircher , Adelheid Cerwenka , Robert Thimme , Maike Hofmann

HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11.

PLoS pathogens
Avec: Cosima Zimmermann , Daniel Kowalewski , Liane Bauersfeld , Andreas Hildenbrand , Carolin Gerke , Magdalena Schwarzmüller , Vu Thuy Khanh Le-Trilling , Stefan Stevanovic , Hartmut Hengel , Frank Momburg , Anne Halenius

Clinical, radiological, and genetic characteristics of 16 patients with ACO2 gene defects: Delineation of an emerging neurometabolic syndrome.

Journal of inherited metabolic disease
Avec: Rajech Sharkia , Klaas J Wierenga , Amit Kessel , Abdussalam Azem , Enrico Bertini , Rosalba Carrozzo , Alessandra Torraco , Paola Goffrini , Camilla Ceccatelli Berti , M Eileen McCormick , Barbara Plecko , Andrea Klein , Lucia Abela , Holger Hengel , Ludger Schöls , Stavit Shalev , Morad Khayat , Muhammad Mahajnah , Ronen Spiegel

Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.

Cell reports. Medicine
Avec: Alexander Carpinteiro , Michael J Edwards , Markus Hoffmann , Georg Kochs , Barbara Gripp , Sebastian Weigang , Constantin Adams , Elisa Carpinteiro , Anne Gulbins , Simone Keitsch , Carolin Sehl , Matthias Soddemann , Barbara Wilker , Markus Kamler , Thomas Bertsch , Karl S Lang , Sameer Patel , Gregory C Wilson , Silke Walter , Hartmut Hengel , Stefan Pöhlmann , Philipp A Lang , Johannes Kornhuber , Katrin Anne Becker , Syed A Ahmad , Klaus Fassbender , Erich Gulbins

Bi-allelic truncating mutations in VWA1 cause neuromyopathy.

Brain : a journal of neurology
Avec: Marcus Deschauer , Holger Hengel , Katrin Rupprich , Martina Kreiß , Beate Schlotter-Weigel , Mona Grimmel , Jakob Admard , Ilka Schneider , Bader Alhaddad , Anastasia Gazou , Marc Sturm , Matthias Vorgerd , Ghassan Balousha , Osama Balousha , Mohammed Falna , Jan S Kirschke , Cornelia Kornblum , Berit Jordan , Torsten Kraya , Tim M Strom , Joachim Weis , Ludger Schöls , Ulrike Schara , Stephan Zierz , Olaf Riess , Thomas Meitinger , Tobias B Haack

Regional Brain and Spinal Cord Volume Loss in Spinocerebellar Ataxia Type 3.

Movement disorders : official journal of the Movement Disorder Society
Avec: Jennifer Faber , Tamara Schaprian , Koyak Berkan , Kathrin Reetz , Marcondes Cavalcante França , Thiago Junqueira Ribeiro de Rezende , Jiang Hong , Weihua Liao , Bart van de Warrenburg , Judith van Gaalen , Alexandra Durr , Fanny Mochel , Paola Giunti , Hector Garcia-Moreno , Ludger Schoels , Holger Hengel , Matthis Synofzik , Benjamin Bender , Gulin Oz , James Joers , Jereon J de Vries , Jun-Suk Kang , Dagmar Timmann-Braun , Heike Jacobi , Jon Infante , Richard Joules , Sandro Romanzetti , Jorn Diedrichsen , Matthias Schmid , Robin Wolz , Thomas Klockgether

Defining diagnostic cutoffs in neurological patients for serum very long chain fatty acids (VLCFA) in genetically confirmed X-Adrenoleukodystrophy.

Scientific reports
Avec: Tim W Rattay , Maren Rautenberg , Anne S Söhn , Holger Hengel , Andreas Traschütz , Benjamin Röben , Stefanie N Hayer , Rebecca Schüle , Sarah Wiethoff , Lena Zeltner , Tobias B Haack , Alexander Cegan , Ludger Schöls , Erwin Schleicher , Andreas Peter

PolyQ-expanded ataxin-3 protein levels in peripheral blood mononuclear cells correlate with clinical parameters in SCA3: a pilot study.

Journal of neurology
Avec: Kathrin Gonsior , Gabriele Anna Kaucher , Patrik Pelz , Dorothea Schumann , Melanie Gansel , Sandra Kuhs , Thomas Klockgether , Sylvie Forlani , Alexandra Durr , Stefan Hauser , Tim W Rattay , Matthis Synofzik , Holger Hengel , Ludger Schöls , Olaf H Rieß , Jeannette Hübener-Schmid

Digital Gait Biomarkers Allow to Capture 1-Year Longitudinal Change in Spinocerebellar Ataxia Type 3.

Movement disorders : official journal of the Movement Disorder Society
Avec: Winfried Ilg , Björn Müller , Jennifer Faber , Judith van Gaalen , Holger Hengel , Ina R Vogt , Guido Hennes , Bart van de Warrenburg , Thomas Klockgether , Ludger Schöls , Matthis Synofzik , Auteur inconnu

Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells.

Cell reports. Medicine
Avec: Manuel Albanese , Hong-Ru Chen , Madeleine Gapp , Maximilian Muenchhoff , Hsiu-Hui Yang , David Peterhoff , Katja Hoffmann , Qianhao Xiao , Adrian Ruhle , Ina Ambiel , Stephanie Schneider , Ernesto Mejías-Pérez , Marcel Stern , Paul R Wratil , Katharina Hofmann , Laura Amann , Linda Jocham , Thimo Fuchs , Alessandro F Ulivi , Simon Besson-Girard , Simon Weidlich , Jochen Schneider , Christoph D Spinner , Kathrin Sutter , Ulf Dittmer , Andreas Humpe , Philipp Baumeister , Andreas Wieser , Simon Rothenfusser , Johannes Bogner , Julia Roider , Percy Knolle , Hartmut Hengel , Ralf Wagner , Vibor Laketa , Oliver T Fackler , Oliver T Keppler

Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination.

Science immunology
Avec: Pascal Irrgang , Juliane Gerling , Katharina Kocher , Dennis Lapuente , Philipp Steininger , Katharina Habenicht , Monika Wytopil , Stephanie Beileke , Simon Schäfer , Jahn Zhong , George Ssebyatika , Thomas Krey , Valeria Falcone , Christine Schülein , Antonia Sophia Peter , Krystelle Nganou-Makamdop , Hartmut Hengel , Jürgen Held , Christian Bogdan , Klaus Überla , Kilian Schober , Thomas H Winkler , Matthias Tenbusch

Allogeneic hematopoietic cell transplantation for adult metachromatic leukodystrophy: a case series.

Blood advances
Avec: Andreas Riedel , Christoph Faul , Kristina Reuss , Jan C Schröder , Peter J Lang , Claudia Lengerke , Nadine Weissert , Holger Hengel , Samuel Gröschel , Ludger Schoels , Wolfgang A Bethge

Unravelling undiagnosed rare disease cases by HiFi long-read genome sequencing.

medRxiv : the preprint server for health sciences
Avec: Wouter Steyaert , Lydia Sagath , German Demidov , Vicente A Yépez , Anna Esteve-Codina , Julien Gagneur , Kornelia Ellwanger , Ronny Derks , Marjan Weiss , Amber den Ouden , Simone van den Heuvel , Hilde Swinkels , Nick Zomer , Marloes Steehouwer , Luke O'Gorman , Galuh Astuti , Kornelia Neveling , Rebecca Schüle , Jishu Xu , Matthis Synofzik , Danique Beijer , Holger Hengel , Ludger Schöls , Kristl G Claeys , Jonathan Baets , Liedewei Van de Vondel , Alessandra Ferlini , Rita Selvatici , Heba Morsy , Marwa Saeed Abd Elmaksoud , Volker Straub , Juliane Müller , Veronica Pini , Luke Perry , Anna Sarkozy , Irina Zaharieva , Francesco Muntoni , Enrico Bugiardini , Kiran Polavarapu , Rita Horvath , Evan Reid , Hanns Lochmüller , Marco Spinazzi , Marco Savarese , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Leslie Matalonga , Steven Laurie , Han G Brunner , Holm Graessner , Sergi Beltran , Stephan Ossowski , Lisenka E L M Vissers , Christian Gilissen , Alexander Hoischen

A novel biallelic loss-of-function mutation in TMCO1 gene confirming and expanding the phenotype spectrum of cerebro-facio-thoracic dysplasia.

American journal of medical genetics. Part A
Avec: Rajech Sharkia , Abdelnaser Zalan , Azhar Jabareen-Masri , Holger Hengel , Ludger Schöls , Amit Kessel , Abdussalam Azem , Muhammad Mahajnah

Prediction of Survival With Long-Term Disease Progression in Most Common Spinocerebellar Ataxia.

Movement disorders : official journal of the Movement Disorder Society
Avec: Alhassane Diallo , Heike Jacobi , Arron Cook , Paola Giunti , Michael H Parkinson , Robyn Labrum , Alexandra Durr , Alexis Brice , Perrine Charles , Cecilia Marelli , Caterina Mariotti , Lorenzo Nanetti , Marta Panzeri , Anna Castaldo , Maria Rakowicz , Rafal Rola , Anna Sulek , Tanja Schmitz-Hübsch , Ludger Schöls , Holger Hengel , Laszlo Baliko , Bela Melegh , Alessandro Filla , Antonella Antenora , Jon Infante , José Berciano , Bart P van de Warrenburg , Dagmar Timmann , Sylvia Boesch , Wolfgang Nachbauer , Massimo Pandolfo , Jörg B Schulz , Peter Bauer , Kang Jun-Suk , Thomas Klockgether , Sophie Tezenas du Montcel

The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity.

Cell reports
Avec: Vu Thuy Khanh Le-Trilling , Tanja Becker , Aharon Nachshon , Noam Stern-Ginossar , Lara Schöler , Sebastian Voigt , Hartmut Hengel , Mirko Trilling

Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity.

Movement disorders : official journal of the Movement Disorder Society
Avec: Holger Hengel , Peter Martus , Jennifer Faber , Hector Garcia-Moreno , Nita Solanky , Paola Giunti , Thomas Klockgether , Kathrin Reetz , Bart P van de Warrenburg , Luís Pereira de Almeida , Magda M Santana , Cristina Januário , Patrick Silva , Andreas Thieme , Jon Infante , Jeroen de Vries , Manuela Lima , Ana F Ferreira , Khalaf Bushara , Heike Jacobi , Chiadi Onyike , Jeremy D Schmahmann , Jeannette Hübener-Schmid , Matthis Synofzik , Ludger Schöls

Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel.

EMBO molecular medicine
Avec: Haizhang Chen , Andrea Maul-Pavicic , Martin Holzer , Magdalena Huber , Ulrich Salzer , Nina Chevalier , Reinhard E Voll , Hartmut Hengel , Philipp Kolb

Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in Households with Children, Southwest Germany, May-August 2020.

Emerging infectious diseases
Avec: Maximilian Stich , Roland Elling , Hanna Renk , Aleš Janda , Sven F Garbade , Barbara Müller , Hans-Georg Kräusslich , Dorit Fabricius , Maria Zernickel , Peter Meissner , Daniela Huzly , Jürgen Grulich-Henn , Anneke Haddad , Tessa Görne , Benedikt Spielberger , Linus Fritsch , Alexandra Nieters , Hartmut Hengel , Andrea N Dietz , Thomas Stamminger , Tina Ganzenmueller , Natalia Ruetalo , Andreas Peter , Jonathan Remppis , Thomas Iftner , Kathrin Jeltsch , Tim Waterboer , Axel R Franz , Georg Friedrich Hoffmann , Corinna Engel , Klaus-Michael Debatin , Burkhard Tönshoff , Philipp Henneke

A Novel, Broad-Acting Peptide Inhibitor of Double-Stranded DNA Virus Gene Expression and Replication.

Frontiers in microbiology
Avec: Zsolt Ruzsics , Katja Hoffmann , André Riedl , Adalbert Krawczyk , Marek Widera , Helene Sertznig , Leonie Schipper , Valeria Kapper-Falcone , Monika Debreczeny , Wolfgang Ernst , Reingard Grabherr , Hartmut Hengel , Hanna Harant

Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infection.

Microbiology spectrum
Avec: Samuel Hofmann , Julius Luther , Verena Plank , Andreas Oswald , Julia Mai , Ilka Simons , Julija Miller , Valeria Falcone , Lea Hansen-Palmus , Hartmut Hengel , Michael Nassal , Ulrike Protzer , Sabrina Schreiner

An iPSC model for POLR3A-associated spastic ataxia: Generation of three unrelated patient cell lines.

Stem cell research
Avec: Kalaivani Manibarathi , Tam Pham , Holger Hengel , Matthis Synofzik , Maike Nagel , Rebecca Schüle

Skin manifestations after immunisation with an adjuvanted recombinant zoster vaccine, Germany, 2020.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Avec: Stefano Orru' , Sibylle Bierbaum , Alexander Enk , Hartmut Hengel , Marcus Hoffelner , Daniela Huzly , Brigitte Keller-Stanislawski , Vera Mahler , Maja Mockenhaupt , Doris Oberle

FARS-ADL across Ataxias: Construct Validity, Sensitivity to Change, and Minimal Important Change.

Movement disorders : official journal of the Movement Disorder Society
Avec: Andreas Traschütz , Zofia Fleszar , Holger Hengel , Thomas Klockgether , Friedrich Erdlenbruch , Björn H Falkenburger , Thomas Klopstock , Özgür Öztop-Çakmak , José Luiz Pedroso , Filippo M Santorelli , Ludger Schöls , Auteur inconnu , Matthis Synofzik

Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Cosima Zimmermann , Gabrielle M Watson , Liane Bauersfeld , Richard Berry , Barbara Ciblis , Huan Lan , Carolin Gerke , Valerie Oberhardt , Jonas Fuchs , Maike Hofmann , Christian Freund , Jamie Rossjohn , Frank Momburg , Hartmut Hengel , Anne Halenius

Predicting clinical phenotypes of metachromatic leukodystrophy based on the arylsulfatase A activity and the ARSA genotype? - Chances and challenges.

Molecular genetics and metabolism
Avec: Vidiyaah Santhanakumaran , Samuel Groeschel , Klaus Harzer , Christiane Kehrer , Saskia Elgün , Stefanie Beck-Wödl , Holger Hengel , Ludger Schöls , Tobias B Haack , Ingeborg Krägeloh-Mann , Lucia Laugwitz

Meningitis without Rash after Reactivation of Varicella Vaccine Strain in a 12-Year-Old Immunocompetent Boy.

Vaccines
Avec: Sibylle Bierbaum , Veronika Fischer , Lutz Briedigkeit , Claudius Werner , Hartmut Hengel , Daniela Huzly

First case of adult onset neuronal intranuclear inclusion disease with both typical radiological signs and NOTCH2NLC repeat expansions in a Caucasian individual.

European journal of neurology
Avec: Iulian V Podar , Daniel A P Gutmann , Florian Harmuth , Tobias B Haack , Stephan Ossowski , Holger Hengel , Antje Bornemann , Ludger Schöls , Oliver Neuhaus

Tiza-

BMJ open
Avec: Stephanie Vollmer-Raschdorf , Jassin Rashidi-Alavijeh , Sebastian Voigt , Hartmut Hengel , Benjamin Borchardt , Daniela Huzly , Eva-Maria Hüßler , Jürgen In der Schmitten , Anne Halenius , Katharina Willuweit , Suzan Botzenhardt , Mirko Trilling , Tobias Boettler , Dorothea Dehnen

Informing pandemic management in Germany with trustworthy, living evidence syntheses and guideline development: Lessons learned from the COVID-19 evidence ecosystem (CEOsys).

Journal of clinical epidemiology
Avec: Angela M Kunzler , Claire Iannizzi , Jacob Burns , Maria-Inti Metzendorf , Sebastian Voigt-Radloff , Vanessa Piechotta , Christoph Schmaderer , Christopher Holzmann-Littig , Felix Balzer , Carina Benstoem , Harald Binder , Martin Boeker , Ulrich Dirnagl , Falk Fichtner , Martin Golinski , Hajo Grundmann , Hartmut Hengel , Jonas Jabs , Winfried V Kern , Ina Kopp , Peter Kranke , Nina Kreuzberger , Sven Laudi , Gregor Lichtner , Klaus Lieb , Andy Maun , Onnen Moerer , Anika Müller , Nico T Mutters , Monika Nothacker , Lisa M Pfadenhauer , Maria Popp , Georg Rüschemeyer , Christine Schmucker , Lukas Schwingshackl , Claudia Spies , Anke Steckelberg , Miriam Stegemann , Daniel Strech , Falk von Dincklage , Stephanie Weibel , Maximilian Markus Wunderlich , Daniela Zöller , Eva Rehfuess , Nicole Skoetz , Joerg J Meerpohl , Auteur inconnu

Multifocal, hypoechogenic nerve thickening in Cerebrotendinous Xanthomatosis.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Avec: Benjamin Roeben , Jennifer Just , Holger Hengel , Friedemann Bender , Peter Pöschl , Matthis Synofzik , Ludger Schöls , Alexander Grimm

Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice.

EMBO molecular medicine
Avec: Carlo Wilke , Eva Haas , Kathrin Reetz , Jennifer Faber , Hector Garcia-Moreno , Magda M Santana , Bart van de Warrenburg , Holger Hengel , Manuela Lima , Alessandro Filla , Alexandra Durr , Bela Melegh , Marcella Masciullo , Jon Infante , Paola Giunti , Manuela Neumann , Jeroen de Vries , Luis Pereira de Almeida , Maria Rakowicz , Heike Jacobi , Rebecca Schüle , Stephan A Kaeser , Jens Kuhle , Thomas Klockgether , Ludger Schöls , Auteur inconnu , Christian Barro , Jeannette Hübener-Schmid , Matthis Synofzik

Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy.

Nature communications
Avec: Holger Hengel , Célia Bosso-Lefèvre , George Grady , Emmanuelle Szenker-Ravi , Hankun Li , Sarah Pierce , Élise Lebigot , Thong-Teck Tan , Michelle Y Eio , Gunaseelan Narayanan , Kagistia Hana Utami , Monica Yau , Nader Handal , Werner Deigendesch , Reinhard Keimer , Hiyam M Marzouqa , Meral Gunay-Aygun , Michael J Muriello , Helene Verhelst , Sarah Weckhuysen , Sonal Mahida , Sakkubai Naidu , Terrence G Thomas , Jiin Ying Lim , Ee Shien Tan , Damien Haye , Michèl A A P Willemsen , Renske Oegema , Wendy G Mitchell , Tyler Mark Pierson , Marisa V Andrews , Marcia C Willing , Lance H Rodan , Tahsin Stefan Barakat , Marjon van Slegtenhorst , Ralitza H Gavrilova , Diego Martinelli , Tal Gilboa , Abdullah M Tamim , Mais O Hashem , Moeenaldeen D AlSayed , Maha M Abdulrahim , Mohammed Al-Owain , Ali Awaji , Adel A H Mahmoud , Eissa A Faqeih , Ali Al Asmari , Sulwan M Algain , Lamyaa A Jad , Hesham M Aldhalaan , Ingo Helbig , David A Koolen , Angelika Riess , Ingeborg Kraegeloh-Mann , Peter Bauer , Suleyman Gulsuner , Hannah Stamberger , Alvin Yu Jin Ng , Sha Tang , Sumanty Tohari , Boris Keren , Laura E Schultz-Rogers , Eric W Klee , Sabina Barresi , Marco Tartaglia , Hagar Mor-Shaked , Sateesh Maddirevula , Amber Begtrup , Aida Telegrafi , Rolph Pfundt , Rebecca Schüle , Brian Ciruna , Carine Bonnard , Mahmoud A Pouladi , James C Stewart , Adam Claridge-Chang , Dirk J Lefeber , Fowzan S Alkuraya , Ajay S Mathuru , Byrappa Venkatesh , Joseph J Barycki , Melanie A Simpson , Saumya S Jamuar , Ludger Schöls , Bruno Reversade

Human Fcγ receptors compete for TGN1412 binding that determines the antibody's effector function.

European journal of immunology
Avec: Simone Dudek , Sabrina Weißmüller , Martina Anzaghe , Lilija Miller , Sarah Sterr , Katja Hoffmann , Hartmut Hengel , Zoe Waibler

Fc-Fusion Drugs Have FcγR/C1q Binding and Signaling Properties That May Affect Their Immunogenicity.

The AAPS journal
Avec: H A Daniel Lagassé , Hartmut Hengel , Basil Golding , Zuben E Sauna

Identification and Functional Characterization of a Novel Fc Gamma-Binding Glycoprotein in Rhesus Cytomegalovirus.

Journal of virology
Avec: Philipp Kolb , Steven Sijmons , Matthew R McArdle , Husam Taher , Jennie Womack , Colette Hughes , Abigail Ventura , Michael A Jarvis , Christiane Stahl-Hennig , Scott Hansen , Louis J Picker , Daniel Malouli , Hartmut Hengel , Klaus Früh

Kinetics of Torque Teno Virus-DNA Plasma Load Predict Rejection in Lung Transplant Recipients.

Transplantation
Avec: Björn C Frye , Sibylle Bierbaum , Valeria Falcone , Thomas C Köhler , Markus Gasplmayr , Ina Hettich , Thorsten Dürk , Marco Idzko , Gernot Zissel , Hartmut Hengel , Joachim Müller-Quernheim

Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation.

eLife
Avec: Philipp Kolb , Katja Hoffmann , Annika Sievert , Henrike Reinhard , Eva Merce-Maldonado , Vu Thuy Khanh Le-Trilling , Anne Halenius , Dominique Gütle , Hartmut Hengel

COVID-19 in a Severely Immunosuppressed Patient With Life-Threatening Eosinophilic Granulomatosis With Polyangiitis.

Frontiers in immunology
Avec: Markus A Schramm , Nils Venhoff , Dirk Wagner , Jens Thiel , Daniela Huzly , Nils Craig-Mueller , Marcus Panning , Hartmut Hengel , Winfried V Kern , Reinhard E Voll

Cytomegalovirus subverts macrophage identity.

Cell
Avec: Sebastian Baasch , Piero Giansanti , Julia Kolter , André Riedl , Aaron James Forde , Solveig Runge , Simon Zenke , Roland Elling , Anne Halenius , Simone Brabletz , Hartmut Hengel , Bernhard Kuster , Thomas Brabletz , Luka Cicin-Sain , Ramon Arens , Andreas Vlachos , Jan Christopher Rohr , Marc Philippe Stemmler , Manfred Kopf , Zsolt Ruzsics , Philipp Henneke

Robust and durable serological response following pediatric SARS-CoV-2 infection.

Nature communications
Avec: Hanna Renk , Alex Dulovic , Alina Seidel , Matthias Becker , Dorit Fabricius , Maria Zernickel , Daniel Junker , Rüdiger Groß , Janis Müller , Alexander Hilger , Sebastian F N Bode , Linus Fritsch , Pauline Frieh , Anneke Haddad , Tessa Görne , Jonathan Remppis , Tina Ganzemueller , Andrea Dietz , Daniela Huzly , Hartmut Hengel , Klaus Kaier , Susanne Weber , Eva-Maria Jacobsen , Philipp D Kaiser , Bjoern Traenkle , Ulrich Rothbauer , Maximilian Stich , Burkhard Tönshoff , Georg F Hoffmann , Barbara Müller , Carolin Ludwig , Bernd Jahrsdörfer , Hubert Schrezenmeier , Andreas Peter , Sebastian Hörber , Thomas Iftner , Jan Münch , Thomas Stamminger , Hans-Jürgen Groß , Martin Wolkewitz , Corinna Engel , Weimin Liu , Marta Rizzi , Beatrice H Hahn , Philipp Henneke , Axel R Franz , Klaus-Michael Debatin , Nicole Schneiderhan-Marra , Ales Janda , Roland Elling

Assessing severe acute respiratory syndrome coronavirus 2 infectivity by reverse-transcription polymerase chain reaction: A systematic review and meta-analysis.

Reviews in medical virology
Avec: Alexey Fomenko , Stephanie Weibel , Helia Moezi , Kristina Menger , Christine Schmucker , Maria-Inti Metzendorf , Edith Motschall , Valeria Falcone , Daniela Huzly , Marcus Panning , Gerta Rücker , Hartmut Hengel

The prodromal phase of hereditary spastic paraplegia type 4: the preSPG4 cohort study.

Brain : a journal of neurology
Avec: Tim W Rattay , Maximilian Völker , Maren Rautenberg , Christoph Kessler , Isabel Wurster , Natalie Winter , Tobias B Haack , Tobias Lindig , Holger Hengel , Matthis Synofzik , Rebecca Schüle , Peter Martus , Ludger Schöls

Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies.

Journal of clinical immunology
Avec: Bengisu Akbil , Tim Meyer , Paula Stubbemann , Charlotte Thibeault , Olga Staudacher , Daniela Niemeyer , Jenny Jansen , Barbara Mühlemann , Jan Doehn , Christoph Tabeling , Christian Nusshag , Cédric Hirzel , David Sökler Sanchez , Alexandra Nieters , Achim Lother , Daniel Duerschmied , Nils Schallner , Jan Nikolaus Lieberum , Dietrich August , Siegbert Rieg , Valeria Falcone , Hartmut Hengel , Uwe Kölsch , Nadine Unterwalder , Ralf-Harto Hübner , Terry C Jones , Norbert Suttorp , Christian Drosten , Klaus Warnatz , Thibaud Spinetti , Joerg C Schefold , Thomas Dörner , Leif Erik Sander , Victor M Corman , Uta Merle , Auteur inconnu , Florian Kurth , Horst von Bernuth , Christian Meisel , Christine Goffinet

Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy.

Genetics in medicine : official journal of the American College of Medical Genetics
Avec: Joohyun Park , Arianna Tucci , Valentina Cipriani , German Demidov , Clarissa Rocca , Jan Senderek , Michaela Butryn , Ana Velic , Tanya Lam , Evangelia Galanaki , Elisa Cali , Letizia Vestito , Reza Maroofian , Natalie Deininger , Maren Rautenberg , Jakob Admard , Gesa-Astrid Hahn , Claudius Bartels , Nienke J H van Os , Rita Horvath , Patrick F Chinnery , May Yung Tiet , Channa Hewamadduma , Marios Hadjivassiliou , George K Tofaris , Auteur inconnu , Nicholas W Wood , Stefanie N Hayer , Friedemann Bender , Benita Menden , Isabell Cordts , Katrin Klein , Huu Phuc Nguyen , Joachim K Krauss , Christian Blahak , Tim M Strom , Marc Sturm , Bart van de Warrenburg , Holger Lerche , Boris Maček , Matthis Synofzik , Stephan Ossowski , Dagmar Timmann , Marc E Wolf , Damian Smedley , Olaf Riess , Ludger Schöls , Henry Houlden , Tobias B Haack , Holger Hengel

Circulating multimeric immune complexes contribute to immunopathology in COVID-19.

Nature communications
Avec: Jakob Ankerhold , Sebastian Giese , Philipp Kolb , Andrea Maul-Pavicic , Reinhard E Voll , Nathalie Göppert , Kevin Ciminski , Clemens Kreutz , Achim Lother , Ulrich Salzer , Wolfgang Bildl , Tim Welsink , Nils G Morgenthaler , Andrea Busse Grawitz , Florian Emmerich , Daniel Steinmann , Daniela Huzly , Martin Schwemmle , Hartmut Hengel , Valeria Falcone

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Holger Hengel 28 collaborations
Ludger Schöls 24 collaborations
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None None 13 collaborations
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