Eylan Yutuc

Affiliations

Swansea University Medical School, Swansea, UK.

ORCID: 0000-0001-9971-1950

Publications (22)

Neuro-oxysterols and neuro-sterols as ligands to nuclear receptors, GPCRs, ligand-gated ion channels and other protein receptors.

British journal of pharmacology

Avec: Yuqin Wang , Eylan Yutuc , William J Griffiths

Developing an Enzyme-Assisted Derivatization Method for Analysis of C

Molecules (Basel, Switzerland)

Avec: Jonas Abdel-Khalik , Peter J Crick , Eylan Yutuc , Yuqin Wang , William J Griffiths

Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates.

The Journal of steroid biochemistry and molecular biology

Avec: Jonas Abdel-Khalik , Thomas Hearn , Alison L Dickson , Peter J Crick , Eylan Yutuc , Karl Austin-Muttitt , Brian W Bigger , Andrew A Morris , Cedric H Shackleton , Peter T Clayton , Takashi Iida , Ria Sircar , Rajat Rohatgi , Hanns-Ulrich Marschall , Jan Sjövall , Ingemar Björkhem , Jonathan G L Mullins , William J Griffiths , Yuqin Wang

Formation and metabolism of oxysterols and cholestenoic acids found in the mouse circulation: Lessons learnt from deuterium-enrichment experiments and the CYP46A1 transgenic mouse.

The Journal of steroid biochemistry and molecular biology

Avec: Peter J Crick , Eylan Yutuc , Jonas Abdel-Khalik , Ahmed Saeed , Christer Betsholtz , Guillem Genove , Ingemar Björkhem , Yuqin Wang , William J Griffiths

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: William J Griffiths , Peter J Crick , Anna Meljon , Spyridon Theofilopoulos , Jonas Abdel-Khalik , Eylan Yutuc , Josie E Parker , Diane E Kelly , Steven L Kelly , Ernest Arenas , Yuqin Wang

Deep mining of oxysterols and cholestenoic acids in human plasma and cerebrospinal fluid: Quantification using isotope dilution mass spectrometry.

Analytica chimica acta

Avec: Eylan Yutuc , Alison L Dickson , Manuela Pacciarini , Lauren Griffiths , Paul R S Baker , Lisa Connell , Anders Öhman , Lars Forsgren , Miles Trupp , Sílvia Vilarinho , Youssef Khalil , Peter T Clayton , Sinan Sari , Buket Dalgic , Philip Höflinger , Ludger Schöls , William J Griffiths , Yuqin Wang

24(

The Journal of biological chemistry

Avec: Spyridon Theofilopoulos , Willy Antoni Abreu de Oliveira , Shanzheng Yang , Eylan Yutuc , Ahmed Saeed , Jonas Abdel-Khalik , Abbe Ullgren , Angel Cedazo-Minguez , Ingemar Björkhem , Yuqin Wang , William J Griffiths , Ernest Arenas

Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders.

Free radical biology & medicine

Avec: William J Griffiths , Eylan Yutuc , Jonas Abdel-Khalik , Peter J Crick , Thomas Hearn , Alison Dickson , Brian W Bigger , Teresa Hoi-Yee Wu , Anu Goenka , Arunabha Ghosh , Simon A Jones , Douglas F Covey , Daniel S Ory , Yuqin Wang

Mining for Oxysterols in

Biomolecules

Avec: Anna Meljon , Peter J Crick , Eylan Yutuc , Joyce L Yau , Jonathan R Seckl , Spyridon Theofilopoulos , Ernest Arenas , Yuqin Wang , William J Griffiths

Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis.

Journal of lipid research

Avec: Philip Höflinger , Stefan Hauser , Eylan Yutuc , Holger Hengel , Lauren Griffiths , Florentine Radelfahr , Owain W Howell , Yuqin Wang , Sonja L Connor , P Barton Duell , Andrea E DeBarber , Peter Martus , Dieter Lütjohann , William J Griffiths , Ludger Schöls

Identification of unusual oxysterols biosynthesised in human pregnancy by charge-tagging and liquid chromatography - mass spectrometry.

Frontiers in endocrinology

Avec: Alison L Dickson , Eylan Yutuc , Catherine A Thornton , Yuqin Wang , William J Griffiths

Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle.

BMC genomics

Avec: Nicholas J Hudson , Antonio Reverter , William J Griffiths , Eylan Yutuc , Yuqin Wang , Angela Jeanes , Sean McWilliam , David W Pethick , Paul L Greenwood

Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients.

Free radical biology & medicine

Avec: William J Griffiths , Jonas Abdel-Khalik , Eylan Yutuc , Gustavo Roman , Margaret Warner , Jan-Åke Gustafsson , Yuqin Wang

The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson's Disease and Their Association With Disease State and Clinical Features.

Frontiers in aging neuroscience

Avec: William J Griffiths , Jonas Abdel-Khalik , Sarah F Moore , Ruwani S Wijeyekoon , Peter J Crick , Eylan Yutuc , Krista Farrell , David P Breen , Caroline H Williams-Gray , Spyridon Theofilopoulos , Ernest Arenas , Miles Trupp , Roger A Barker , Yuqin Wang

Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development.

iScience

Avec: James Hennegan , Aled H Bryant , Lauren Griffiths , Matthieu Trigano , Oliver J M Bartley , Joanna J Bartlett , Carys Minahan , Willy Antoni Abreu de Oliveira , Eylan Yutuc , Sotirios Ntikas , Christos S Bartsocas , Margarita Markouri , Eleni Antoniadou , Ioanna Laina , Owain W Howell , Meng Li , Yuqin Wang , William J Griffiths , Emma L Lane , Mariah J Lelos , Spyridon Theofilopoulos

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Ruochen Zang , James Brett Case , Eylan Yutuc , Xiucui Ma , Sheng Shen , Maria Florencia Gomez Castro , Zhuoming Liu , Qiru Zeng , Haiyan Zhao , Juhee Son , Paul W Rothlauf , Alex J B Kreutzberger , Gaopeng Hou , Hu Zhang , Sayantan Bose , Xin Wang , Michael D Vahey , Kartik Mani , William J Griffiths , Tom Kirchhausen , Daved H Fremont , Haitao Guo , Abhinav Diwan , Yuqin Wang , Michael S Diamond , Sean P J Whelan , Siyuan Ding

Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging.

Analytical chemistry

Avec: Roberto Angelini , Eylan Yutuc , Mark F Wyatt , Jillian Newton , Fowzi A Yusuf , Lauren Griffiths , Benjamin J Cooze , Dana El Assad , Gilles Frache , Wei Rao , Luke B Allen , Zeljka Korade , Thu T A Nguyen , Rathnayake A C Rathnayake , Stephanie M Cologna , Owain W Howell , Malcolm R Clench , Yuqin Wang , William J Griffiths

Cholesterol metabolism pathways - are the intermediates more important than the products?

The FEBS journal

Avec: Yuqin Wang , Eylan Yutuc , William J Griffiths

Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Eylan Yutuc , Roberto Angelini , Mark Baumert , Natalia Mast , Irina Pikuleva , Jillian Newton , Malcolm R Clench , David O F Skibinski , Owain W Howell , Yuqin Wang , William J Griffiths

Assessment of cholesterol homeostasis in the living human brain.

Science translational medicine

Avec: Ahmed Haider , Chunyu Zhao , Lu Wang , Zhiwei Xiao , Jian Rong , Xiaotian Xia , Zhen Chen , Stefanie K Pfister , Natalia Mast , Eylan Yutuc , Jiahui Chen , Yinlong Li , Tuo Shao , Geoffrey I Warnock , Alyaa Dawoud , Theresa R Connors , Derek H Oakley , Huiyi Wei , Jinghao Wang , Zhihua Zheng , Hao Xu , April T Davenport , James B Daunais , Richard S Van , Yihan Shao , Yuqin Wang , Ming-Rong Zhang , Catherine Gebhard , Irina Pikuleva , Allan I Levey , William J Griffiths , Steven H Liang

HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta.

Open biology

Avec: Alison Dickson , Eylan Yutuc , Catherine A Thornton , James E Dunford , Udo Oppermann , Yuqin Wang , William J Griffiths

Mass Spectrometry Imaging of Cholesterol and Oxysterols.

Advances in experimental medicine and biology

Avec: William J Griffiths , Eylan Yutuc , Yuqin Wang

Réseau de co-auteurs

Yuqin Wang 22 collaborations

William J Griffiths 22 collaborations

Jonas Abdel-Khalik 8 collaborations

Peter J Crick 7 collaborations

Spyridon Theofilopoulos 5 collaborations

Ernest Arenas 4 collaborations

Lauren Griffiths 4 collaborations

Owain W Howell 4 collaborations

Alison L Dickson 3 collaborations

Ingemar Björkhem 3 collaborations

Thomas Hearn 2 collaborations

Brian W Bigger 2 collaborations

Peter T Clayton 2 collaborations

Ahmed Saeed 2 collaborations

Anna Meljon 2 collaborations

Miles Trupp 2 collaborations

Philip Höflinger 2 collaborations

Ludger Schöls 2 collaborations

Willy Antoni Abreu de Oliveira 2 collaborations

Alison Dickson 2 collaborations

Catherine A Thornton 2 collaborations

Roberto Angelini 2 collaborations

Jillian Newton 2 collaborations

Malcolm R Clench 2 collaborations

Natalia Mast 2 collaborations

Irina Pikuleva 2 collaborations

Karl Austin-Muttitt 1 collaboration

Andrew A Morris 1 collaboration

Cedric H Shackleton 1 collaboration

Takashi Iida 1 collaboration

Ria Sircar 1 collaboration

Rajat Rohatgi 1 collaboration

Hanns-Ulrich Marschall 1 collaboration

Jan Sjövall 1 collaboration

Jonathan G L Mullins 1 collaboration

Christer Betsholtz 1 collaboration

Guillem Genove 1 collaboration

Josie E Parker 1 collaboration

Diane E Kelly 1 collaboration

Steven L Kelly 1 collaboration

Manuela Pacciarini 1 collaboration

Paul R S Baker 1 collaboration

Lisa Connell 1 collaboration

Anders Öhman 1 collaboration

Lars Forsgren 1 collaboration

Sílvia Vilarinho 1 collaboration

Youssef Khalil 1 collaboration

Sinan Sari 1 collaboration

Buket Dalgic 1 collaboration

Shanzheng Yang 1 collaboration

Abbe Ullgren 1 collaboration

Angel Cedazo-Minguez 1 collaboration

Teresa Hoi-Yee Wu 1 collaboration

Anu Goenka 1 collaboration

Arunabha Ghosh 1 collaboration

Simon A Jones 1 collaboration

Douglas F Covey 1 collaboration

Daniel S Ory 1 collaboration

Joyce L Yau 1 collaboration

Jonathan R Seckl 1 collaboration

Stefan Hauser 1 collaboration

Holger Hengel 1 collaboration

Florentine Radelfahr 1 collaboration

Sonja L Connor 1 collaboration

P Barton Duell 1 collaboration

Andrea E DeBarber 1 collaboration

Peter Martus 1 collaboration

Dieter Lütjohann 1 collaboration

Nicholas J Hudson 1 collaboration

Antonio Reverter 1 collaboration

Angela Jeanes 1 collaboration

Sean McWilliam 1 collaboration

David W Pethick 1 collaboration

Paul L Greenwood 1 collaboration

Gustavo Roman 1 collaboration

Margaret Warner 1 collaboration

Jan-Åke Gustafsson 1 collaboration

Sarah F Moore 1 collaboration

Ruwani S Wijeyekoon 1 collaboration

Krista Farrell 1 collaboration

David P Breen 1 collaboration

Caroline H Williams-Gray 1 collaboration

Roger A Barker 1 collaboration

James Hennegan 1 collaboration

Aled H Bryant 1 collaboration

Matthieu Trigano 1 collaboration

Oliver J M Bartley 1 collaboration

Joanna J Bartlett 1 collaboration

Carys Minahan 1 collaboration

Sotirios Ntikas 1 collaboration

Christos S Bartsocas 1 collaboration

Margarita Markouri 1 collaboration

Eleni Antoniadou 1 collaboration

Ioanna Laina 1 collaboration

Meng Li 1 collaboration

Emma L Lane 1 collaboration

Mariah J Lelos 1 collaboration

Ruochen Zang 1 collaboration

James Brett Case 1 collaboration

Xiucui Ma 1 collaboration

Sheng Shen 1 collaboration

Maria Florencia Gomez Castro 1 collaboration

Zhuoming Liu 1 collaboration

Qiru Zeng 1 collaboration

Haiyan Zhao 1 collaboration

Juhee Son 1 collaboration

Paul W Rothlauf 1 collaboration

Alex J B Kreutzberger 1 collaboration

Gaopeng Hou 1 collaboration

Hu Zhang 1 collaboration

Sayantan Bose 1 collaboration

Xin Wang 1 collaboration

Michael D Vahey 1 collaboration

Kartik Mani 1 collaboration

Tom Kirchhausen 1 collaboration

Daved H Fremont 1 collaboration

Haitao Guo 1 collaboration

Abhinav Diwan 1 collaboration

Michael S Diamond 1 collaboration

Sean P J Whelan 1 collaboration

Siyuan Ding 1 collaboration

Mark F Wyatt 1 collaboration

Fowzi A Yusuf 1 collaboration

Benjamin J Cooze 1 collaboration

Dana El Assad 1 collaboration

Gilles Frache 1 collaboration

Wei Rao 1 collaboration

Luke B Allen 1 collaboration

Zeljka Korade 1 collaboration

Thu T A Nguyen 1 collaboration

Rathnayake A C Rathnayake 1 collaboration

Stephanie M Cologna 1 collaboration

Mark Baumert 1 collaboration

David O F Skibinski 1 collaboration

Ahmed Haider 1 collaboration

Chunyu Zhao 1 collaboration

Lu Wang 1 collaboration

Zhiwei Xiao 1 collaboration

Jian Rong 1 collaboration

Xiaotian Xia 1 collaboration

Zhen Chen 1 collaboration

Stefanie K Pfister 1 collaboration

Jiahui Chen 1 collaboration

Yinlong Li 1 collaboration

Tuo Shao 1 collaboration

Geoffrey I Warnock 1 collaboration

Alyaa Dawoud 1 collaboration

Theresa R Connors 1 collaboration

Derek H Oakley 1 collaboration

Huiyi Wei 1 collaboration

Jinghao Wang 1 collaboration

Zhihua Zheng 1 collaboration

Hao Xu 1 collaboration

April T Davenport 1 collaboration

James B Daunais 1 collaboration

Richard S Van 1 collaboration

Yihan Shao 1 collaboration

Ming-Rong Zhang 1 collaboration

Catherine Gebhard 1 collaboration

Allan I Levey 1 collaboration

Steven H Liang 1 collaboration

James E Dunford 1 collaboration

Udo Oppermann 1 collaboration