Coincidental SARS-CoV-2 infection and mRNA vaccination: a case report addressing the most important clinical questions.


Journal

Infection
ISSN: 1439-0973
Titre abrégé: Infection
Pays: Germany
ID NLM: 0365307

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 03 03 2021
accepted: 16 04 2021
pubmed: 9 5 2021
medline: 19 8 2021
entrez: 8 5 2021
Statut: ppublish

Résumé

The case describes the coincidental mRNA vaccination and SARS-CoV-2 infection of a 31-year-old physician addressing the theoretical considerations and recommendations for further actions in such a particular constellation that we will expect more often in the near future.

Identifiants

pubmed: 33963523
doi: 10.1007/s15010-021-01613-w
pii: 10.1007/s15010-021-01613-w
pmc: PMC8104037
doi:

Substances chimiques

COVID-19 Vaccines 0
Vaccines, Synthetic 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

785-788

Informations de copyright

© 2021. The Author(s).

Références

Tedros Adhanom Ghebreyesus. WHO Director—General’s opening remarks at the media briefing on COVID-19—11 March 2020 [Internet]. 2020. https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020 . cited 9 Jan 2021.
Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine. N Engl J Med. 2020;383:2603–15.
doi: 10.1056/NEJMoa2034577
Long Q-X, Liu B-Z, Deng H-J, Wu G-C, Deng K, Chen Y-K, et al. Antibody responses to SARS-CoV-2 in patients with COVID-19. Nat Med. 2020;26:845–8.
doi: 10.1038/s41591-020-0897-1
Qu J, Wu C, Li X, Zhang G, Jiang Z, Li X, et al. Profile of immunoglobulin g and igm antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020;71:2255–8.
doi: 10.1093/cid/ciaa489
Lu L, Zhang H, Zhan M, Jiang J, Yin H, Dauphars DJ, et al. Antibody response and therapy in COVID-19 patients: what can be learned for vaccine development? Sci China Life Sci. 2020;63:1833–49.
doi: 10.1007/s11427-020-1859-y
Sahin U, Muik A, Derhovanessian E, Vogler I, Kranz LM, Vormehr M, et al. COVID-19 vaccine BNT162b1 elicits human antibody and T H 1 T cell responses. Nature. 2020;586:594–9.
doi: 10.1038/s41586-020-2814-7
Walsh EE, Robert W. Frenck J, Falsey AR, Kitchin N, Absalon J, Gurtman A, et al. Safety and Immunogenicity of two RNA-based COVID-19 vaccine candidates. N Engl J Med. Massachusetts Medical Society; 2020. https://www.nejm.org/doi/ https://doi.org/10.1056/NEJMoa2027906 . Cited 10 Jan 2021.
Martin LK, Hollaus A, Stahuber A, Hübener C, Fraccaroli A, Tischer J, et al. Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B. PLOS Pathog. 2018;14:e1006991.
doi: 10.1371/journal.ppat.1006991
Mulligan MJ, Lyke KE, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults. Nature. 2020;586:589–93.
doi: 10.1038/s41586-020-2639-4
Interim Clinical Considerations for Use of mRNA COVID-19 Vaccines | CDC [Internet]. 2021. https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html . Cited 23 Feb 2021.

Auteurs

Ozan E Eren (OE)

Department of Neurology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany. ozan.eren@med.uni-muenchen.de.

Matthias Tonon (M)

Department of Neurology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.

Florian Schöberl (F)

Department of Neurology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.

Clemens Gießen-Jung (C)

Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.

Andreas Moosmann (A)

German Center for Infection Research, Munich Partner Site, Munich, Germany.
Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.

Alexandra Hollaus (A)

German Center for Infection Research, Munich Partner Site, Munich, Germany.
Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.

Maximilian Muenchhoff (M)

Max Von Pettenkofer Institute, LMU Munich, Munich, Germany.
German Center for Infection Research, Munich Partner Site, Munich, Germany.
COVID-19 Registry of the LMU Munich (CORKUM), University Hospital, LMU Munich, Munich, Germany.

Konstantinos Dimitriadis (K)

Department of Neurology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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