Simone Kreth

Affiliations

Department of Anesthesiology, University Hospital, LMU Munich, 81377 Munich, Germany.
Walter-Brendel Center of Experimental Medicine, Faculty of Medicine, LMU Munich, 81377 Munich, Germany.

Publications (22)

The IL-1 Antagonist Anakinra Attenuates Glioblastoma Aggressiveness by Dampening Tumor-Associated Inflammation.

Cancers

Avec: Max Hübner , David Effinger , Tingting Wu , Gabriele Strauß , Kristin Pogoda , Friedrich-Wilhelm Kreth , Simone Kreth

Myeloid-Derived Suppressor Cells Mediate Immunosuppression After Cardiopulmonary Bypass.

Critical care medicine

Avec: Max Hübner , Roland Tomasi , David Effinger , Tingting Wu , Gregor Klein , Martin Bender , Erich Kilger , Gerd Juchem , Edzard Schwedhelm , Simone Kreth

A ketogenic diet substantially reshapes the human metabolome.

Clinical nutrition (Edinburgh, Scotland)

Avec: David Effinger , Simon Hirschberger , Polina Yoncheva , Annika Schmid , Till Heine , Patrick Newels , Burkhard Schütz , Chen Meng , Michael Gigl , Karin Kleigrewe , Lesca-Miriam Holdt , Daniel Teupser , Simone Kreth

MicroRNA-93 acts as an "anti-inflammatory tumor suppressor" in glioblastoma.

Neuro-oncology advances

Avec: Max Hübner , Nicholas Moellhoff , David Effinger , Christian Ludwig Hinske , Simon Hirschberger , Tingting Wu , Martin Bernhard Müller , Gabriele Strauß , Friedrich-Wilhelm Kreth , Simone Kreth

iTReX: Interactive exploration of mono- and combination therapy dose response profiling data.

Pharmacological research

Avec: Dina ElHarouni , Yannick Berker , Heike Peterziel , Apurva Gopisetty , Laura Turunen , Sina Kreth , Sabine A Stainczyk , Ina Oehme , Vilja Pietiäinen , Natalie Jäger , Olaf Witt , Matthias Schlesner , Sina Oppermann

Cell-Crossing Functional Network Driven by microRNA-125a Regulates Endothelial Permeability and Monocyte Trafficking in Acute Inflammation.

Frontiers in immunology

Avec: Martin Bernhard Müller , Max Hübner , Lei Li , Stephanie Tomasi , Valena Ließke , David Effinger , Simon Hirschberger , Kristin Pogoda , Markus Sperandio , Simone Kreth

[Immunomodulation by nutritional intervention in critically ill patients].

Die Anaesthesiologie

Avec: Simon Hirschberger , Annika Schmid , Simone Kreth

Ketone Bodies Improve Human CD8

Frontiers in medicine

Avec: Simon Hirschberger , Luca Gellert , David Effinger , Maximilian Muenchhoff , Markus Herrmann , Josef-Maria Briegel , Bernhard Zwißler , Simone Kreth

Impact of carbohydrate-reduced nutrition in septic patients on ICU: study protocol for a prospective randomised controlled trial.

BMJ open

Avec: Tim Rahmel , Max Hübner , Björn Koos , Alexander Wolf , Katrin-Maria Willemsen , Gabriele Strauß , David Effinger , Michael Adamzik , Simone Kreth

Hypoxic-inflammatory responses under acute hypoxia: In Vitro experiments and prospective observational expedition trial.

International journal of molecular sciences

Avec: Tobias Kammerer , Valentina Faihs , Nikolai Hulde , Manfred Stangl , Florian Brettner , Markus Rehm , Mareike Horstmann , Julia Kröpfl , Christina Spengler , Simone Kreth , Simon Schäfer

Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma.

Cancers

Avec: Michael Müller , Lisa Rösch , Sara Najafi , Charlotte Gatzweiler , Johannes Ridinger , Xenia F Gerloff , David T W Jones , Jochen Baßler , Sina Kreth , Sabine Stainczyk , Karen Frese , Benjamin Meder , Frank Westermann , Till Milde , Heike Peterziel , Olaf Witt , Ina Oehme

Super enhancers define regulatory subtypes and cell identity in neuroblastoma.

Nature cancer

Avec: Moritz Gartlgruber , Ashwini Kumar Sharma , Andrés Quintero , Daniel Dreidax , Selina Jansky , Young-Gyu Park , Sina Kreth , Johanna Meder , Daria Doncevic , Paul Saary , Umut H Toprak , Naveed Ishaque , Elena Afanasyeva , Elisa Wecht , Jan Koster , Rogier Versteeg , Thomas G P Grünewald , David T W Jones , Stefan M Pfister , Kai-Oliver Henrich , Johan van Nes , Carl Herrmann , Frank Westermann

Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis.

EBioMedicine

Avec: Yvonn Heun , Joachim Pircher , Thomas Czermak , Philipp Bluem , Georg Hupel , Monica Bohmer , Bjoern F Kraemer , Kristin Pogoda , Alexander Pfeifer , Markus Woernle , Andrea Ribeiro , Max Hübner , Simone Kreth , Ralf A Claus , Sebastian Weis , Luisa Ungelenk , Florian Krötz , Ulrich Pohl , Hanna Mannell

Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming.

EMBO molecular medicine

Avec: Simon Hirschberger , Gabriele Strauß , David Effinger , Xaver Marstaller , Alicia Ferstl , Martin B Müller , Tingting Wu , Max Hübner , Tim Rahmel , Hannah Mascolo , Nicole Exner , Julia Heß , Friedrich W Kreth , Kristian Unger , Simone Kreth

Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models.

Cancers

Avec: Charlotte Gatzweiler , Johannes Ridinger , Sonja Herter , Xenia F Gerloff , Dina ElHarouni , Yannick Berker , Roland Imle , Lukas Schmitt , Sina Kreth , Sabine Stainczyk , Simay Ayhan , Sara Najafi , Damir Krunic , Karen Frese , Benjamin Meder , David Reuss , Petra Fiesel , Kathrin Schramm , Mirjam Blattner-Johnson , David T W Jones , Ana Banito , Frank Westermann , Sina Oppermann , Till Milde , Heike Peterziel , Olaf Witt , Ina Oehme

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.

Nature cancer

Avec: Hamed Alborzinia , Andrés F Flórez , Sina Kreth , Lena M Brückner , Umut Yildiz , Moritz Gartlgruber , Dorett I Odoni , Gernot Poschet , Karolina Garbowicz , Chunxuan Shao , Corinna Klein , Jasmin Meier , Petra Zeisberger , Michal Nadler-Holly , Matthias Ziehm , Franziska Paul , Jürgen Burhenne , Emma Bell , Marjan Shaikhkarami , Roberto Würth , Sabine A Stainczyk , Elisa M Wecht , Jochen Kreth , Michael Büttner , Naveed Ishaque , Matthias Schlesner , Barbara Nicke , Carlo Stresemann , María Llamazares-Prada , Jan H Reiling , Matthias Fischer , Ido Amit , Matthias Selbach , Carl Herrmann , Stefan Wölfl , Kai-Oliver Henrich , Thomas Höfer , Andreas Trumpp , Frank Westermann

An open-label, randomized controlled trial to assess a ketogenic diet in critically ill patients with sepsis.

Science translational medicine

Avec: Tim Rahmel , David Effinger , Thilo Bracht , Leonore Griep , Björn Koos , Barbara Sitek , Max Hübner , Simon Hirschberger , Jale Basten , Nina Timmesfeld , Michael Adamzik , Simone Kreth

A Functional Network Driven by MicroRNA-125a Regulates Monocyte Trafficking in Acute Inflammation.

International journal of molecular sciences

Avec: Stephanie Tomasi , Lei Li , Ludwig Christian Hinske , Roland Tomasi , Martina Amini , Gabriele Strauß , Martin Bernhard Müller , Simon Hirschberger , Sven Peterss , David Effinger , Kristin Pogoda , Simone Kreth , Max Hübner

Identification of suitable controls for miRNA quantification in T-cells and whole blood cells in sepsis.

Scientific reports

Avec: Simon Hirschberger , Max Hübner , Gabriele Strauß , David Effinger , Michael Bauer , Sebastian Weis , Evangelos J Giamarellos-Bourboulis , Simone Kreth

Dynamic 18F-FET PET is a powerful imaging biomarker in gadolinium-negative gliomas.

Neuro-oncology

Avec: Mathias Kunz , Nathalie Lisa Albert , Marcus Unterrainer , Christian la Fougere , Rupert Egensperger , Ulrich Schüller , Juergen Lutz , Simone Kreth , Jörg-Christian Tonn , Friedrich-Wilhelm Kreth , Niklas Thon

T-Cell Response in a Cardiac Xenotransplant Model.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

Avec: Roland Tomasi , Maliha Tariq , Max Hübner , Gabriele Strauss , Matthias Längin , Catharina Zeuzem-Lampert , Stephanie Vandewiele , Simone Kreth , Jan-Michael Abicht

Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer.

Cell reports

Avec: Sebastian M Dieter , Christine Siegl , Paula L Codó , Mario Huerta , Anna L Ostermann-Parucha , Erik Schulz , Martina K Zowada , Sylvia Martin , Karin Laaber , Ali Nowrouzi , Mona Blatter , Sina Kreth , Frank Westermann , Axel Benner , Ulrike Uhrig , Kerstin Putzker , Joe Lewis , Andrea Haegebarth , Dominik Mumberg , Simon J Holton , Joerg Weiske , Lena-Marit Toepper , Ulrike Scheib , Gerhard Siemeister , Claudia R Ball , Bernhard Kuster , Gabriele Stoehr , Hannes Hahne , Sarah Johannes , Martin Lange , Friederike Herbst , Hanno Glimm

Réseau de co-auteurs

Max Hübner 11 collaborations

David Effinger 11 collaborations

Simon Hirschberger 9 collaborations

Gabriele Strauß 6 collaborations

Sina Kreth 6 collaborations

Frank Westermann 5 collaborations

Tingting Wu 4 collaborations

Kristin Pogoda 4 collaborations

Friedrich-Wilhelm Kreth 3 collaborations

Roland Tomasi 3 collaborations

Martin Bernhard Müller 3 collaborations

Heike Peterziel 3 collaborations

Ina Oehme 3 collaborations

Olaf Witt 3 collaborations

Tim Rahmel 3 collaborations

David T W Jones 3 collaborations

Annika Schmid 2 collaborations

Dina ElHarouni 2 collaborations

Yannick Berker 2 collaborations

Sabine A Stainczyk 2 collaborations

Matthias Schlesner 2 collaborations

Sina Oppermann 2 collaborations

Lei Li 2 collaborations

Stephanie Tomasi 2 collaborations

Björn Koos 2 collaborations

Michael Adamzik 2 collaborations

Sara Najafi 2 collaborations

Charlotte Gatzweiler 2 collaborations

Johannes Ridinger 2 collaborations

Xenia F Gerloff 2 collaborations

Sabine Stainczyk 2 collaborations

Karen Frese 2 collaborations

Benjamin Meder 2 collaborations

Till Milde 2 collaborations

Moritz Gartlgruber 2 collaborations

Naveed Ishaque 2 collaborations

Kai-Oliver Henrich 2 collaborations

Carl Herrmann 2 collaborations

Sebastian Weis 2 collaborations

Gregor Klein 1 collaboration

Martin Bender 1 collaboration

Erich Kilger 1 collaboration

Gerd Juchem 1 collaboration

Edzard Schwedhelm 1 collaboration

Polina Yoncheva 1 collaboration

Till Heine 1 collaboration

Patrick Newels 1 collaboration

Burkhard Schütz 1 collaboration

Chen Meng 1 collaboration

Michael Gigl 1 collaboration

Karin Kleigrewe 1 collaboration

Lesca-Miriam Holdt 1 collaboration

Daniel Teupser 1 collaboration

Nicholas Moellhoff 1 collaboration

Christian Ludwig Hinske 1 collaboration

Apurva Gopisetty 1 collaboration

Laura Turunen 1 collaboration

Vilja Pietiäinen 1 collaboration

Natalie Jäger 1 collaboration

Valena Ließke 1 collaboration

Markus Sperandio 1 collaboration

Luca Gellert 1 collaboration

Maximilian Muenchhoff 1 collaboration

Markus Herrmann 1 collaboration

Josef-Maria Briegel 1 collaboration

Bernhard Zwißler 1 collaboration

Alexander Wolf 1 collaboration

Katrin-Maria Willemsen 1 collaboration

Tobias Kammerer 1 collaboration

Valentina Faihs 1 collaboration

Nikolai Hulde 1 collaboration

Manfred Stangl 1 collaboration

Florian Brettner 1 collaboration

Markus Rehm 1 collaboration

Mareike Horstmann 1 collaboration

Julia Kröpfl 1 collaboration

Christina Spengler 1 collaboration

Simon Schäfer 1 collaboration

Michael Müller 1 collaboration

Lisa Rösch 1 collaboration

Jochen Baßler 1 collaboration

Ashwini Kumar Sharma 1 collaboration

Andrés Quintero 1 collaboration

Daniel Dreidax 1 collaboration

Selina Jansky 1 collaboration

Young-Gyu Park 1 collaboration

Johanna Meder 1 collaboration

Daria Doncevic 1 collaboration

Paul Saary 1 collaboration

Umut H Toprak 1 collaboration

Elena Afanasyeva 1 collaboration

Elisa Wecht 1 collaboration

Jan Koster 1 collaboration

Rogier Versteeg 1 collaboration

Thomas G P Grünewald 1 collaboration

Stefan M Pfister 1 collaboration

Johan van Nes 1 collaboration

Yvonn Heun 1 collaboration

Joachim Pircher 1 collaboration

Thomas Czermak 1 collaboration

Philipp Bluem 1 collaboration

Georg Hupel 1 collaboration

Monica Bohmer 1 collaboration

Bjoern F Kraemer 1 collaboration

Alexander Pfeifer 1 collaboration

Markus Woernle 1 collaboration

Andrea Ribeiro 1 collaboration

Ralf A Claus 1 collaboration

Luisa Ungelenk 1 collaboration

Florian Krötz 1 collaboration

Ulrich Pohl 1 collaboration

Hanna Mannell 1 collaboration

Xaver Marstaller 1 collaboration

Alicia Ferstl 1 collaboration

Martin B Müller 1 collaboration

Hannah Mascolo 1 collaboration

Nicole Exner 1 collaboration

Julia Heß 1 collaboration

Friedrich W Kreth 1 collaboration

Kristian Unger 1 collaboration

Sonja Herter 1 collaboration

Roland Imle 1 collaboration

Lukas Schmitt 1 collaboration

Simay Ayhan 1 collaboration

Damir Krunic 1 collaboration

David Reuss 1 collaboration

Petra Fiesel 1 collaboration

Kathrin Schramm 1 collaboration

Mirjam Blattner-Johnson 1 collaboration

Ana Banito 1 collaboration

Hamed Alborzinia 1 collaboration

Andrés F Flórez 1 collaboration

Lena M Brückner 1 collaboration

Umut Yildiz 1 collaboration

Dorett I Odoni 1 collaboration

Gernot Poschet 1 collaboration

Karolina Garbowicz 1 collaboration

Chunxuan Shao 1 collaboration

Corinna Klein 1 collaboration

Jasmin Meier 1 collaboration

Petra Zeisberger 1 collaboration

Michal Nadler-Holly 1 collaboration

Matthias Ziehm 1 collaboration

Franziska Paul 1 collaboration

Jürgen Burhenne 1 collaboration

Emma Bell 1 collaboration

Marjan Shaikhkarami 1 collaboration

Roberto Würth 1 collaboration

Elisa M Wecht 1 collaboration

Jochen Kreth 1 collaboration

Michael Büttner 1 collaboration

Barbara Nicke 1 collaboration

Carlo Stresemann 1 collaboration

María Llamazares-Prada 1 collaboration

Jan H Reiling 1 collaboration

Matthias Fischer 1 collaboration

Ido Amit 1 collaboration

Matthias Selbach 1 collaboration

Stefan Wölfl 1 collaboration

Thomas Höfer 1 collaboration

Andreas Trumpp 1 collaboration

Thilo Bracht 1 collaboration

Leonore Griep 1 collaboration

Barbara Sitek 1 collaboration

Jale Basten 1 collaboration

Nina Timmesfeld 1 collaboration

Ludwig Christian Hinske 1 collaboration

Martina Amini 1 collaboration

Sven Peterss 1 collaboration

Michael Bauer 1 collaboration

Evangelos J Giamarellos-Bourboulis 1 collaboration

Mathias Kunz 1 collaboration

Nathalie Lisa Albert 1 collaboration

Marcus Unterrainer 1 collaboration

Christian la Fougere 1 collaboration

Rupert Egensperger 1 collaboration

Ulrich Schüller 1 collaboration

Juergen Lutz 1 collaboration

Jörg-Christian Tonn 1 collaboration

Niklas Thon 1 collaboration

Maliha Tariq 1 collaboration

Gabriele Strauss 1 collaboration

Matthias Längin 1 collaboration

Catharina Zeuzem-Lampert 1 collaboration

Stephanie Vandewiele 1 collaboration

Jan-Michael Abicht 1 collaboration

Sebastian M Dieter 1 collaboration

Christine Siegl 1 collaboration

Paula L Codó 1 collaboration

Mario Huerta 1 collaboration

Anna L Ostermann-Parucha 1 collaboration

Erik Schulz 1 collaboration

Martina K Zowada 1 collaboration

Sylvia Martin 1 collaboration

Karin Laaber 1 collaboration

Ali Nowrouzi 1 collaboration

Mona Blatter 1 collaboration

Axel Benner 1 collaboration

Ulrike Uhrig 1 collaboration

Kerstin Putzker 1 collaboration

Joe Lewis 1 collaboration

Andrea Haegebarth 1 collaboration

Dominik Mumberg 1 collaboration

Simon J Holton 1 collaboration

Joerg Weiske 1 collaboration

Lena-Marit Toepper 1 collaboration

Ulrike Scheib 1 collaboration

Gerhard Siemeister 1 collaboration

Claudia R Ball 1 collaboration

Bernhard Kuster 1 collaboration

Gabriele Stoehr 1 collaboration

Hannes Hahne 1 collaboration

Sarah Johannes 1 collaboration

Martin Lange 1 collaboration

Friederike Herbst 1 collaboration

Hanno Glimm 1 collaboration