Laurent Debarbieux

Affiliations

Department of Microbiology, Institut Pasteur, F-75015 Paris, France. Electronic address: laurent.debarbieux@pasteur.fr.

Publications (35)

The Battle Within: Interactions of Bacteriophages and Bacteria in the Gastrointestinal Tract.

Cell host & microbe

Avec: Luisa De Sordi , Marta Lourenço , Laurent Debarbieux

Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden

Microbiology spectrum

Avec: Quentin Lamy-Besnier , Lorenzo Chaffringeon , Marta Lourenço , Rayford B Payne , Jimmy T Trinh , Jennifer A Schwartz , Alexander Sulakvelidze , Laurent Debarbieux

Improving the intestinal lipidome coverage in a gnotobiotic mouse model using UHPLC-MS-based approach through optimization of mobile phase modifiers and column selection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Avec: Habiba Selmi , Alesia Walker , Laurent Debarbieux , Philippe Schmitt-Kopplin

Metapopulation model of phage therapy of an acute

bioRxiv : the preprint server for biology

Avec: Rogelio A Rodriguez-Gonzalez , Quentin Balacheff , Laurent Debarbieux , Jacopo Marchi , Joshua S Weitz

A nanoluciferase-encoded bacteriophage illuminates viral infection dynamics of

ISME communications

Avec: Sophia Zborowsky , Quentin Balacheff , Ioanna Theodorou , Rokhaya Kane , Raphaëlle Delattre , Joshua S Weitz , Régis Tournebize , Laurent Debarbieux

The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages.

Cell host & microbe

Avec: Marta Lourenço , Lorenzo Chaffringeon , Quentin Lamy-Besnier , Thierry Pédron , Pascal Campagne , Claudia Eberl , Marion Bérard , Bärbel Stecher , Laurent Debarbieux , Luisa De Sordi

[A century of research on bacteriophages].

Virologie (Montrouge, France)

Avec: Mireille Ansaldi , Pascale Boulanger , Charlotte Brives , Laurent Debarbieux , Nicolas Dufour , Rémy Froissart , Sylvain Gandon , Claire Le Hénaff , Marie-Agnès Petit , Eduardo Rocha , Clara Torres-Barceló

Intestinal Bacteriophage Therapy: Looking for Optimal Efficacy.

Clinical microbiology reviews

Avec: François Javaudin , Chloé Latour , Laurent Debarbieux , Quentin Lamy-Besnier

Viral Host Range database, an online tool for recording, analyzing and disseminating virus-host interactions.

Bioinformatics (Oxford, England)

Avec: Quentin Lamy-Besnier , Bryan Brancotte , Hervé Ménager , Laurent Debarbieux

Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community.

Microbiology resource announcements

Avec: Quentin Lamy-Besnier , Romain Koszul , Laurent Debarbieux , Martial Marbouty

The dynamic interplay of bacteriophage, bacteria and the mammalian host during phage therapy.

iScience

Avec: Jacopo Marchi , Sophia Zborowsky , Laurent Debarbieux , Joshua S Weitz

Optimizing the Timing and Composition of Therapeutic Phage Cocktails: A Control-Theoretic Approach.

Bulletin of mathematical biology

Avec: Guanlin Li , Chung Yin Leung , Yorai Wardi , Laurent Debarbieux , Joshua S Weitz

"I will survive": A tale of bacteriophage-bacteria coevolution in the gut.

Gut microbes

Avec: Luisa De Sordi , Marta Lourenço , Laurent Debarbieux

Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy.

Cell reports

Avec: Raphaëlle Delattre , Jérémy Seurat , Feyrouz Haddad , Thu-Thuy Nguyen , Baptiste Gaborieau , Rokhaya Kane , Nicolas Dufour , Jean-Damien Ricard , Jérémie Guedj , Laurent Debarbieux

The Selection of Antibiotic- and Bacteriophage-Resistant Pseudomonas aeruginosa Is Prevented by Their Combination.

Microbiology spectrum

Avec: Aude A Ferran , Marlène Z Lacroix , Ophélie Gourbeyre , Alicia Huesca , Baptiste Gaborieau , Laurent Debarbieux , Alain Bousquet-Mélou

Complete genome sequences of two

Microbiology resource announcements

Avec: Issa Ndiaye , Laurent Debarbieux , Moussa Moise Diagne , Ousmane Sow , Abdoulaye Cissé , Bissoume Sambe Ba , Cheikh Fall , Yakhya Dieye , Ndongo Dia , Abdoulaye Seck , Guillaume Constantin de Magny

High-Throughput Bacteriophage Testing with Potency Determination: Validation of an Automated Pipetting and Phage Drop-Off Method.

Biomedicines

Avec: Nicolas Dufour , Raphaëlle Delattre , Laurent Debarbieux

Metapopulation model of phage therapy of an acute

mSystems

Avec: Rogelio A Rodriguez-Gonzalez , Quentin Balacheff , Laurent Debarbieux , Jacopo Marchi , Joshua S Weitz

Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated

Nanoscale

Avec: Yankel Chekli , Stanislas Thiriet-Rupert , Céline Caillet , Fabienne Quilès , Hélène Le Cordier , Emilie Deshayes , Benjamin Bardiaux , Thierry Pédron , Marie Titecat , Laurent Debarbieux , Jean-Marc Ghigo , Grégory Francius , Jérôme F L Duval , Christophe Beloin

Stable coexistence between an archaeal virus and the dominant methanogen of the human gut.

Nature communications

Avec: Diana P Baquero , Sofia Medvedeva , Camille Martin-Gallausiaux , Nika Pende , Anna Sartori-Rupp , Stéphane Tachon , Thierry Pedron , Laurent Debarbieux , Guillaume Borrel , Simonetta Gribaldo , Mart Krupovic

Phage Therapy of Pneumonia Is Not Associated with an Overstimulation of the Inflammatory Response Compared to Antibiotic Treatment in Mice.

Antimicrobial agents and chemotherapy

Avec: Nicolas Dufour , Raphaëlle Delattre , Anne Chevallereau , Jean-Damien Ricard , Laurent Debarbieux

Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage.

Science (New York, N.Y.)

Avec: Aurélie Fluckiger , Romain Daillère , Mohamed Sassi , Barbara Susanne Sixt , Peng Liu , Friedemann Loos , Corentin Richard , Catherine Rabu , Maryam Tidjani Alou , Anne-Gaëlle Goubet , Fabien Lemaitre , Gladys Ferrere , Lisa Derosa , Connie P M Duong , Meriem Messaoudene , Andréanne Gagné , Philippe Joubert , Luisa De Sordi , Laurent Debarbieux , Sylvain Simon , Clara-Maria Scarlata , Maha Ayyoub , Belinda Palermo , Francesco Facciolo , Romain Boidot , Richard Wheeler , Ivo Gomperts Boneca , Zsofia Sztupinszki , Krisztian Papp , Istvan Csabai , Edoardo Pasolli , Nicola Segata , Carlos Lopez-Otin , Zoltan Szallasi , Fabrice Andre , Valerio Iebba , Valentin Quiniou , David Klatzmann , Jacques Boukhalil , Saber Khelaifia , Didier Raoult , Laurence Albiges , Bernard Escudier , Alexander Eggermont , Fathia Mami-Chouaib , Paola Nistico , François Ghiringhelli , Bertrand Routy , Nathalie Labarrière , Vincent Cattoir , Guido Kroemer , Laurence Zitvogel

[Antibacterial applications of bacteriophages].

Virologie (Montrouge, France)

Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy.

bioRxiv : the preprint server for biology

Avec: Sophia Zborowsky , Jeremy Seurat , Quentin Balacheff , Chau Nguyen Ngoc Minh , Marie Titecat , Emma Evrard , Rogelio A Rodriguez-Gonzalez , Jacopo Marchi , Joshua S Weitz , Laurent Debarbieux

The role of the animal host in the management of bacteriophage resistance during phage therapy.

Current opinion in virology

Avec: Baptiste Gaborieau , Laurent Debarbieux

Variable fitness effects of bacteriophage resistance mutations in

Journal of virology

Avec: Baptiste Gaborieau , Raphaëlle Delattre , Sandrine Adiba , Olivier Clermont , Erick Denamur , Jean-Damien Ricard , Laurent Debarbieux

Multi-strain phage induced clearance of bacterial infections.

bioRxiv : the preprint server for biology

Avec: Jacopo Marchi , Chau Nguyen Ngoc Minh , Laurent Debarbieux , Joshua S Weitz

Isolation and Characterization of Bacteriophages That Infect

Viruses

Avec: Carolina M Mizuno , Tiffany Luong , Robert Cederstrom , Mart Krupovic , Laurent Debarbieux , Dwayne R Roach

The intestinal virome: lessons from animal models.

Current opinion in virology

Avec: Lorenzo Chaffringeon , Quentin Lamy-Besnier , Laurent Debarbieux , Luisa De Sordi

The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection.

Cell host & microbe

Avec: Marta Lourenço , Lorenzo Chaffringeon , Quentin Lamy-Besnier , Marie Titécat , Thierry Pédron , Odile Sismeiro , Rachel Legendre , Hugo Varet , Jean-Yves Coppée , Marion Bérard , Luisa De Sordi , Laurent Debarbieux

Repetitive Exposure to Bacteriophage Cocktails against

Viruses

Avec: Chantal Weissfuss , Sandra-Maria Wienhold , Magdalena Bürkle , Baptiste Gaborieau , Judith Bushe , Ulrike Behrendt , Romina Bischoff , Imke H E Korf , Sarah Wienecke , Antonia Dannheim , Holger Ziehr , Christine Rohde , Achim D Gruber , Jean-Damien Ricard , Laurent Debarbieux , Martin Witzenrath , Geraldine Nouailles

Human Neutrophil Response to

Viruses

Avec: Dwayne R Roach , Benoît Noël , Sylvie Chollet-Martin , Mathieu de Jode , Vanessa Granger , Laurent Debarbieux , Luc de Chaisemartin

Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.

Microbiome

Avec: Quentin Lamy-Besnier , Amaury Bignaud , Julian R Garneau , Marie Titecat , Devon E Conti , Alexandra Von Strempel , Marc Monot , Bärbel Stecher , Romain Koszul , Laurent Debarbieux , Martial Marbouty

Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice.

PLoS pathogens

Avec: Alexandra von Strempel , Anna S Weiss , Johannes Wittmann , Marta Salvado Silva , Diana Ring , Esther Wortmann , Thomas Clavel , Laurent Debarbieux , Karin Kleigrewe , Bärbel Stecher

Prediction of strain level phage-host interactions across the Escherichia genus using only genomic information.

Nature microbiology

Avec: Baptiste Gaborieau , Hugo Vaysset , Florian Tesson , Inès Charachon , Nicolas Dib , Juliette Bernier , Tanguy Dequidt , Héloïse Georjon , Olivier Clermont , Pascal Hersen , Laurent Debarbieux , Jean-Damien Ricard , Erick Denamur , Aude Bernheim

Réseau de co-auteurs

Quentin Lamy-Besnier 8 collaborations

Joshua S Weitz 7 collaborations

Luisa De Sordi 6 collaborations

Baptiste Gaborieau 6 collaborations

Marta Lourenço 5 collaborations

Jacopo Marchi 5 collaborations

Raphaëlle Delattre 5 collaborations

Nicolas Dufour 5 collaborations

Jean-Damien Ricard 5 collaborations

Lorenzo Chaffringeon 4 collaborations

Quentin Balacheff 4 collaborations

Rogelio A Rodriguez-Gonzalez 3 collaborations

Sophia Zborowsky 3 collaborations

Thierry Pédron 3 collaborations

Bärbel Stecher 3 collaborations

Marie Titecat 3 collaborations

Rokhaya Kane 2 collaborations

Marion Bérard 2 collaborations

Mireille Ansaldi 2 collaborations

Pascale Boulanger 2 collaborations

Charlotte Brives 2 collaborations

Rémy Froissart 2 collaborations

Sylvain Gandon 2 collaborations

Claire Le Hénaff 2 collaborations

Marie-Agnès Petit 2 collaborations

Eduardo Rocha 2 collaborations

Clara Torres-Barceló 2 collaborations

Romain Koszul 2 collaborations

Martial Marbouty 2 collaborations

Mart Krupovic 2 collaborations

Chau Nguyen Ngoc Minh 2 collaborations

Olivier Clermont 2 collaborations

Erick Denamur 2 collaborations

Dwayne R Roach 2 collaborations

Rayford B Payne 1 collaboration

Jimmy T Trinh 1 collaboration

Jennifer A Schwartz 1 collaboration

Alexander Sulakvelidze 1 collaboration

Habiba Selmi 1 collaboration

Alesia Walker 1 collaboration

Philippe Schmitt-Kopplin 1 collaboration

Ioanna Theodorou 1 collaboration

Régis Tournebize 1 collaboration

Pascal Campagne 1 collaboration

Claudia Eberl 1 collaboration

François Javaudin 1 collaboration

Chloé Latour 1 collaboration

Bryan Brancotte 1 collaboration

Hervé Ménager 1 collaboration

Guanlin Li 1 collaboration

Chung Yin Leung 1 collaboration

Yorai Wardi 1 collaboration

Jérémy Seurat 1 collaboration

Feyrouz Haddad 1 collaboration

Thu-Thuy Nguyen 1 collaboration

Jérémie Guedj 1 collaboration

Aude A Ferran 1 collaboration

Marlène Z Lacroix 1 collaboration

Ophélie Gourbeyre 1 collaboration

Alicia Huesca 1 collaboration

Alain Bousquet-Mélou 1 collaboration

Issa Ndiaye 1 collaboration

Moussa Moise Diagne 1 collaboration

Ousmane Sow 1 collaboration

Abdoulaye Cissé 1 collaboration

Bissoume Sambe Ba 1 collaboration

Cheikh Fall 1 collaboration

Yakhya Dieye 1 collaboration

Ndongo Dia 1 collaboration

Abdoulaye Seck 1 collaboration

Guillaume Constantin de Magny 1 collaboration

Yankel Chekli 1 collaboration

Stanislas Thiriet-Rupert 1 collaboration

Céline Caillet 1 collaboration

Fabienne Quilès 1 collaboration

Hélène Le Cordier 1 collaboration

Emilie Deshayes 1 collaboration

Benjamin Bardiaux 1 collaboration

Jean-Marc Ghigo 1 collaboration

Grégory Francius 1 collaboration

Jérôme F L Duval 1 collaboration

Christophe Beloin 1 collaboration

Diana P Baquero 1 collaboration

Sofia Medvedeva 1 collaboration

Camille Martin-Gallausiaux 1 collaboration

Nika Pende 1 collaboration

Anna Sartori-Rupp 1 collaboration

Stéphane Tachon 1 collaboration

Thierry Pedron 1 collaboration

Guillaume Borrel 1 collaboration

Simonetta Gribaldo 1 collaboration

Anne Chevallereau 1 collaboration

Aurélie Fluckiger 1 collaboration

Romain Daillère 1 collaboration

Mohamed Sassi 1 collaboration

Barbara Susanne Sixt 1 collaboration

Peng Liu 1 collaboration

Friedemann Loos 1 collaboration

Corentin Richard 1 collaboration

Catherine Rabu 1 collaboration

Maryam Tidjani Alou 1 collaboration

Anne-Gaëlle Goubet 1 collaboration

Fabien Lemaitre 1 collaboration

Gladys Ferrere 1 collaboration

Lisa Derosa 1 collaboration

Connie P M Duong 1 collaboration

Meriem Messaoudene 1 collaboration

Andréanne Gagné 1 collaboration

Philippe Joubert 1 collaboration

Sylvain Simon 1 collaboration

Clara-Maria Scarlata 1 collaboration

Maha Ayyoub 1 collaboration

Belinda Palermo 1 collaboration

Francesco Facciolo 1 collaboration

Romain Boidot 1 collaboration

Richard Wheeler 1 collaboration

Ivo Gomperts Boneca 1 collaboration

Zsofia Sztupinszki 1 collaboration

Krisztian Papp 1 collaboration

Istvan Csabai 1 collaboration

Edoardo Pasolli 1 collaboration

Nicola Segata 1 collaboration

Carlos Lopez-Otin 1 collaboration

Zoltan Szallasi 1 collaboration

Fabrice Andre 1 collaboration

Valerio Iebba 1 collaboration

Valentin Quiniou 1 collaboration

David Klatzmann 1 collaboration

Jacques Boukhalil 1 collaboration

Saber Khelaifia 1 collaboration

Didier Raoult 1 collaboration

Laurence Albiges 1 collaboration

Bernard Escudier 1 collaboration

Alexander Eggermont 1 collaboration

Fathia Mami-Chouaib 1 collaboration

Paola Nistico 1 collaboration

François Ghiringhelli 1 collaboration

Bertrand Routy 1 collaboration

Nathalie Labarrière 1 collaboration

Vincent Cattoir 1 collaboration

Guido Kroemer 1 collaboration

Laurence Zitvogel 1 collaboration

Jeremy Seurat 1 collaboration

Emma Evrard 1 collaboration

Sandrine Adiba 1 collaboration

Carolina M Mizuno 1 collaboration

Tiffany Luong 1 collaboration

Robert Cederstrom 1 collaboration

Marie Titécat 1 collaboration

Odile Sismeiro 1 collaboration

Rachel Legendre 1 collaboration

Hugo Varet 1 collaboration

Jean-Yves Coppée 1 collaboration

Chantal Weissfuss 1 collaboration

Sandra-Maria Wienhold 1 collaboration

Magdalena Bürkle 1 collaboration

Judith Bushe 1 collaboration

Ulrike Behrendt 1 collaboration

Romina Bischoff 1 collaboration

Imke H E Korf 1 collaboration

Sarah Wienecke 1 collaboration

Antonia Dannheim 1 collaboration

Holger Ziehr 1 collaboration

Christine Rohde 1 collaboration

Achim D Gruber 1 collaboration

Martin Witzenrath 1 collaboration

Geraldine Nouailles 1 collaboration

Benoît Noël 1 collaboration

Sylvie Chollet-Martin 1 collaboration

Mathieu de Jode 1 collaboration

Vanessa Granger 1 collaboration

Luc de Chaisemartin 1 collaboration

Amaury Bignaud 1 collaboration

Julian R Garneau 1 collaboration

Devon E Conti 1 collaboration

Alexandra Von Strempel 1 collaboration

Marc Monot 1 collaboration

Alexandra von Strempel 1 collaboration

Anna S Weiss 1 collaboration

Johannes Wittmann 1 collaboration

Marta Salvado Silva 1 collaboration

Diana Ring 1 collaboration

Esther Wortmann 1 collaboration

Thomas Clavel 1 collaboration

Karin Kleigrewe 1 collaboration

Hugo Vaysset 1 collaboration

Florian Tesson 1 collaboration

Inès Charachon 1 collaboration

Nicolas Dib 1 collaboration

Juliette Bernier 1 collaboration

Tanguy Dequidt 1 collaboration

Héloïse Georjon 1 collaboration

Pascal Hersen 1 collaboration

Aude Bernheim 1 collaboration